[1]陆岸锋.妊娠期高血糖暴露对子代近期结局影响的研究进展[J].医学信息,2024,37(10):170-174188.[doi:10.3969/j.issn.1006-1959.2024.10.037]
 LU An-feng.Research Progress on Effects of Hyperglycemia Exposure During Pregnancy on Offspring Short-term Outcomes[J].Journal of Medical Information,2024,37(10):170-174188.[doi:10.3969/j.issn.1006-1959.2024.10.037]
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妊娠期高血糖暴露对子代近期结局影响的研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年10期
页码:
170-174188
栏目:
综述
出版日期:
2024-05-15

文章信息/Info

Title:
Research Progress on Effects of Hyperglycemia Exposure During Pregnancy on Offspring Short-term Outcomes
文章编号:
1006-1959(2024)10-0170-06
作者:
陆岸锋
(钦州市妇幼保健院新生儿科,广西 钦州 535099)
Author(s):
LU An-feng
(Department of Neonatology,Qinzhou Maternal and Child Health Care Hospital,Qinzhou 535099,Guangxi,China)
关键词:
妊娠期高血糖临床结局胎儿发育新生儿
Keywords:
Hyperglycemia in pregnancyClinical outcomeFetal developmentNewborn
分类号:
R72
DOI:
10.3969/j.issn.1006-1959.2024.10.037
文献标志码:
A
摘要:
妊娠期高血糖是孕期常见的一种临床表现,包括妊娠期糖尿病、糖尿病前期(空腹血糖受损和糖尿量受损)、孕前糖尿病合并妊娠。随着社会经济的发展,人们生活方式和饮食结构发生改变,近年来妊娠期高血糖的发病率呈现上升的趋势。母体糖代谢的异常对子代近期结局有不良影响,子代生后早期易出现低血糖、呼吸窘迫、巨大儿、心血管疾病等,严重危害子代的健康。本文对妊娠期高血糖暴露相关的子代近期结局进行阐述,以期优化该群体的诊疗,改善预后。
Abstract:
Hyperglycemia in pregnancy is a common clinical manifestation during pregnancy, including gestational diabetes mellitus, prediabetes (impaired fasting glucose and impaired glycosuria), and pre pregnancy diabetes with pregnancy. With the development of social economy, people’s lifestyle and dietary structure have changed. In recent years, the incidence rate of hyperglycemia in pregnancy has increased. Abnormal maternal glucose metabolism has a negative impact on the recent outcome of offspring. Early after birth, offspring are prone to hypoglycemia, respiratory distress, macrosomia, cardiovascular disease, and other serious health hazards. This article intends to elaborate on the recent outcomes of offspring related to hyperglycemia exposure during pregnancy, with a view to optimizing the diagnosis and treatment of this population and improving the prognosis.

参考文献/References:

[1]Magliano DJ,Boyko EJ,IDF Diabetes Atlas 10th edition scientific committee.IDF DIABETES ATLAS [Internet][M].10th ed.Brussels:International Diabetes Federation,2021.[2]Yildiz Atar H,Baatz JE,Ryan RM.Molecular Mechanisms of Maternal Diabetes Effects on Fetal and Neonatal Surfactant[J].Children (Basel),2021,8(4):281.[3]Kokhanov A.Congenital Abnormalities in the Infant of a Diabetic Mother[J].Neoreviews,2022,23(5):e319-e327.[4]Hod M,Kapur A,Sacks DA,et al.The International Federation of Gynecology and Obstetrics (FIGO) Initiative on gestational diabetes mellitus: A pragmatic guide for diagnosis,management,and care[J].Int J Gynaecol Obstet,2015,131(Suppl 3):S173-S211.[5]Riskin A,Itzchaki O,Bader D,et al.Perinatal Outcomes in Infants of Mothers with Diabetes in Pregnancy[J].Isr Med Assoc J,2020,22(9):569-575.[6]Mortier I,Blanc J,Tosello B,et al.Is gestational diabetes an independent risk factor of neonatal severe respiratory distress syndrome after 34 weeks of gestation? A prospective study[J].Arch Gynecol Obstet,2017,296:1071-1077.[7]Bricelj K,Tul N,Lucovnik M,et al.Neonatal respiratory morbidity in late-preterm births in pregnancies with and without gestational diabetes mellitus[J].J Matern Fetal Neonatal Med,2017,30(4):377-379.[8]Werner EF,Romano ME,Rouse DJ,et al.Association of Gestational Diabetes Mellitus With Neonatal Respiratory Morbidity[J].Obstet Gynecol,2019,133:349.[9]倪松平,华孝真,张素春.2型糖尿病和妊娠期糖尿病对新生儿呼吸窘迫综合征的影响[J].中国儿童保健杂志,2022,30(4):450-453.[10]王华,侯东敏,陈永萍.妊娠期糖尿病对晚期早产儿呼吸系统疾病的影响[J].中华新生儿科杂志(中英文),2018,33(1):34-38.[11]Helle E,Priest JR.Maternal Obesity and Diabetes Mellitus as Risk Factors for Congenital Heart Disease in the Offspring[J].J Am Heart Assoc,2020,9:e011541[12]罗柳,黄鹏,王婷婷,等.母亲糖尿病及UCP2基因多态性与子代先天性心脏病关联的病例对照研究[J].中国当代儿科杂志,2020,22(10):1092-1099.[13]Yovera L,Zaharia M,Jachymski T,et al.Impact of gestational diabetes mellitus on fetal cardiac morphology and function: cohort comparison of second- and third-trimester fetuses[J].Ultrasound Obstet Gynecol,2021,57(4):607-613.[14]邢继伟,张巍,焦颖.妊娠期糖尿病对新生儿心脏发育的影响[J].中华新生儿科杂志(中英文),2019,34(6):413-417.[15]Dolk H,McCullough N,Callaghan S,et al.Risk factors for congenital heart disease: The Baby Hearts Study,a population-based case-control study[J].PLoS One,2020,15(2):e0227908.[16]Nakano H,Fajardo VM,Nakano A.The role of glucose in physiological and pathological heart formation[J].Dev Biol,2021,475:222-233.[17]Miranda JO,Cerqueira RJ,Ramalho C,et al.Fetal cardiac function in maternal diabetes: a conventional and speckle-tracking echocardiographic study[J].J Am Soc Echocard,2018,31(3):333-341.[18]Giread?觍 R,Socolov D,Mih?觍lceanu E,et al.Evaluation of Fetal Cardiac Geometry and Contractility in Gestational Diabetes Mellitus by Two-Dimensional Speckle-Tracking Technology[J].Diagnostics(Basel),2022,12(9):2053.[19]马征戈,李春擎,李江华,等.妊娠期糖尿病患者不同血糖控制水平对胎儿心脏结构和功能的影响[J].山东医药,2020,60(14):57-59.[20]李爱国,赵普,奚晓红,等.妊娠期糖尿病产妇的新生儿生后早期心脏血流动力学变化[J].中华围产医学杂志,2015,18(12):927-931.[21]Li JY,Li RJ,Ma N,et al.Assessment of right ventricular strain in children with repaired tetralogy of Fallot using speckle tracking imaging[J].Chin Med J (Engl),2019,132(6):744-748.[22]Ji S,Zhou W,Li X,et al.Maternal hyperglycemia disturbs neocortical neurogenesis via epigenetic regulation in C57BL/6J mice[J].Cell Death Dis,2019,10(3):211.[23]廖凯斌,李潮生.高血糖对血管内皮细胞损伤机制的影响[J].医学综述,2019,25(11):2128-2131.[24]Nattero-Chávez L,Luque-Ramírez M,Escobar-Morreale HF.Systemic endocrinopathies (thyroid conditions and diabetes): impact on postnatal life of the offspring[J].Fertil Steril,2019,111(6):1076-1091.[25]Nogueira Avelar E Silva R,Yu Y,Liew Z,et al.Associations of Maternal Diabetes During Pregnancy With Psychiatric Disorders in Offspring During the First 4 Decades of Life in a Population-Based Danish Birth Cohort[J].JAMA Netw Open,2021,4(10):e2128005.[26]顾雪娟,金晓红,唐玉红.振幅整合脑电图联合新生儿神经行为测定评估妊娠期糖尿病产妇新生儿脑发育[J].中国计划生育学杂志,2022,30(11):2552-2556.[27]王艳霞,刘桂华,欧萍,等.福州市妊娠期糖尿病母亲子代体格与智能发育及其影响因素分析[J].中国妇幼卫生杂志,2019,10(2):5-9.[28]Saito Y,Kobayashi S,Ito S,et al.Neurodevelopmental delay up to the age of 4 years in infants born to women with gestational diabetes mellitus: The Japan Environment and Children’s Study[J].J Diabetes Investig,2022,13(12):2054-2062.[29]吴红花.胰岛素抵抗与妊娠期糖尿病[J].中华糖尿病杂志,2020,12(7):436-439.[30]Sertsu A,Nigussie K,Eyeberu A,et al.Determinants of neonatal hypoglycemia among neonates admitted at Hiwot Fana Comprehensive Specialized University Hospital,Eastern Ethiopia: A retrospective cross-sectional study[J].SAGE Open Med,2022,10:20503121221141801.[31]Begum S,Dey SK,Fatema K.Neonatal Glycemic Status of Infants of Diabetic Mothers in a Tertiary Care Hospital[J].Indian J Endocrinol Metab,2018,22(5):621-626.[32]齐光昭.54例新生儿低血糖的诊断与治疗[J].吉林医学,2012,33(3):592-593.[33]阳一平,蔡娇,王榜珍,等.新生儿低血糖脑损伤高危因素分析[J].癫痫与神经电生理学杂志,2021,30(2):92-97.[34]尤金英,李建国,郭景华.新生儿低血糖脑损伤临床特征与脑电图监测[J].临床儿科杂志,2012,30(3):230-233.[35]朱付立,魏丽.新生儿低血糖性脑损伤的临床及MRI特点分析[J].黑龙江医学,2019,43(5):502-504.[36]吕媛,朱玲玲,陈凌,等.低血糖新生儿血糖波动与脑损伤的相关性[J].临床儿科杂志,2017,35(9):652-654.[37]Hughes MM,Black RE,Katz J.2500-g Low Birth Weight Cutoff: History and Implications for Future Research and Policy[J].Matern Child Health J,2017,21(2):283-289.[38]Shen L,Wang J,Duan Y,et al.Prevalence of low birth weight and macrosomia estimates based on heaping adjustment method in China[J].Sci Rep,2021,11(1):15016.[39]Muche AA,Olayemi OO,Gete YK.Gestational diabetes mellitus increased the risk of adverse neonatal outcomes: A prospective cohort study in Northwest Ethiopia[J].Midwifery,2020,87:102713.[40]Nahavandi S,Seah JM,Shub A,et al.Biomarkers for Macrosomia Prediction in Pregnancies Affected by Diabetes[J].Front Endocrinol (Lausanne),2018,9:407.[41]Malaza N,Masete M,Adam S,et al.A Systematic Review to Compare Adverse Pregnancy Outcomes in Women with Pregestational Diabetes and Gestational Diabetes[J].Int J Environ Res Public Health,2022,19(17):10846.[42]Lee KW,Ching SM,Hoo FK,et al.Neonatal outcomes and its association among gestational diabetes mellitus with and without depression,anxiety and stress symptoms in Malaysia: A cross-sectional study[J].Midwifery,2020,81:102586.[43]Liu X,Wu N,Al-Mureish A.A Review on Research Progress in the Application of Glycosylated Hemoglobin and Glycated Albumin in the Screening and Monitoring of Gestational Diabetes[J].Int J Gen Med,2021,14:1155-1165.[44]徐梅佳,薛春燕,路黎娟.妊娠期糖尿病患者HbA1c表达与BMI、新生儿体重及妊娠结局的相关性[J].中国计划生育学杂志,2022,30(8):1766-1770,1775.[45]黄泽荣,郭光萍,邓星梅,等.巨大儿发生率及其影响因素研究[J].卫生软科学,2023,37(3):26-30.[46]Chawanpaiboon S,Vogel JP,Moller AB,et al.Global,regional,and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis[J].Lancet Glob Health,2019,7(1):e37-e46.[47]夏雪梅,周梦林,陈丹青.妊娠期糖尿病孕妇自发性早产的高危因素分析[J].实用妇产科杂志,2022,38(8):621-624.[48]Ye W,Luo C,Huang J,et al.Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis[J].BMJ,2022,377:e067946.

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更新日期/Last Update: 1900-01-01