[1]古丽娜尔·阿不都拉.幽门螺旋杆菌与胃食管反流病的相关性研究[J].医学信息,2024,37(13):90-93.[doi:10.3969/j.issn.1006-1959.2024.13.017]
　Study on the Correlation Between Helicobacter Pylori and Gastroesophageal Reflux Disease.Study on the Correlation Between Helicobacter Pylori and Gastroesophageal Reflux Disease[J].Journal of Medical Information,2024,37(13):90-93.[doi:10.3969/j.issn.1006-1959.2024.13.017]
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幽门螺旋杆菌与胃食管反流病的相关性研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年13期
页码:
90-93
栏目:
论著
出版日期:
2024-07-01

文章信息/Info

Title:
Study on the Correlation Between Helicobacter Pylori and Gastroesophageal Reflux Disease
文章编号:
1006-1959（2024）13-0090-04
作者:
古丽娜尔·阿不都拉
（喀什地区第一人民医院健康管理中心，新疆 喀什 844000）
Author(s):
Study on the Correlation Between Helicobacter Pylori and Gastroesophageal Reflux Disease
(Health Management Center of the First People’s Hospital of Kashgar,Kashgar 844000,Xinjiang,China)
关键词:
幽门螺旋杆菌; 胃食管反流病; 咽喉炎
Keywords:
elicobacter pylori; Gastroesophageal reflux disease; Pharyngolaryngitis
分类号:
R573.9
DOI:
10.3969/j.issn.1006-1959.2024.13.017
文献标志码:
A
摘要:
目的 研究幽门螺旋杆菌（Hp）与胃食管反流病的相关性。方法 选取2022年1月-2023年1月在我院诊治的63例胃食管反流病患者为研究对象，进行Hp检测，观察胃食管反流病患者Hp阳性率、不同分级胃食管反流患者Hp感染程度，单分析胃食管反流病患者Hp感染的影响因素。结果 63例胃食管反流患者Hp阳性率为63.49%；A级、B级患者Hp感染++、Hp+++、Hp++++占比均低于C级、D级患者，Hp感染+占比高于C级、D级患者（P＜0.05）；不同年龄、性别、病程、合并吸烟、合并喝酒的胃食管反流病患者Hp感染率比较，差异无统计学意义（P＞0.05），合并咽喉炎、合并消化道症状的胃食管反流病患者Hp感染率比较，差异有统计学意义（P＜0.05）；多因素 Logistic 回归分析显示，咽喉炎、消化道症状、胃食管反流分级是胃食管反流病患者Hp感染的危险因素（P＜0.05）。结论 胃食管反流病患者Hp感染率相对较高，且胃食管反流越严重的患者Hp感染程度越严重，Hp可能在胃食管反流病中起保护作用。同时胃食管反流患者Hp感染与合并咽喉炎、消化道症状存、胃食管反流分级存在一定的相关性，在治疗胃食管反流病时应加强高危患者Hp的检测，以为临床治疗提供准确的参考依据。
Abstract:
Objective To study the correlation between Helicobacter pylori (Hp) and gastroesophageal reflux disease.Methods A total of 63 patients with gastroesophageal reflux disease diagnosed and treated in our hospital from January 2022 to January 2023 were selected as the research objects. Hp was detected. The positive rate of Hp in patients with gastroesophageal reflux disease and the degree of Hp infection in patients with different grades of gastroesophageal reflux were observed. The influencing factors of Hp infection in patients with gastroesophageal reflux disease were analyzed.Results The positive rate of Hp in 63 patients with gastroesophageal reflux was 63.49%. The proportion of Hp infection++, Hp+++ and Hp++++ in patients with grade A and grade B was lower than that in patients with grade C and grade D, and the proportion of Hp infection+ was higher than that in patients with grade C and grade D (P<0.05). There was significant difference in Hp infection rate between patients with gastroesophageal reflux disease complicated with laryngitis and gastrointestinal symptoms (P<0.05). Multivariate logistic regression analysis showed that pharyngitis, gastrointestinal symptoms, and gastroesophageal reflux grade were risk factors for Hp infection in patients with gastroesophageal reflux disease (P<0.05).Conclusion The infection rate of Hp in patients with gastroesophageal reflux disease is relatively high, and the more serious the gastroesophageal reflux is, the more serious the Hp infection is. Hp may play a protective role in gastroesophageal reflux disease. At the same time, there is a certain correlation between Hp infection in patients with gastroesophageal reflux and laryngitis, gastrointestinal symptoms and gastroesophageal reflux grading. In the treatment of gastroesophageal reflux disease, the detection of Hp in high-risk patients should be strengthened to provide accurate reference for clinical treatment.

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更新日期/Last Update: 1900-01-01