[1]刘同昊,李元海,鲁显福,等.食管癌根治术后发生胸腔积液的危险因素分析[J].医学信息,2023,36(22):68-72，77.[doi:10.3969/j.issn.1006-1959.2023.22.014]
　LIU Tong-hao,LI Yuan-hai,LU Xian-fu,et al.Analysis of Risk Factors for Pleural Effusion After Radical Resection of Esophageal Cancer[J].Journal of Medical Information,2023,36(22):68-72，77.[doi:10.3969/j.issn.1006-1959.2023.22.014]
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食管癌根治术后发生胸腔积液的危险因素分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年22期
页码:
68-72，77
栏目:
论著
出版日期:
2023-11-15

文章信息/Info

Title:
Analysis of Risk Factors for Pleural Effusion After Radical Resection of Esophageal Cancer
文章编号:
1006-1959（2023）22-0068-06
作者:
刘同昊; 李元海; 鲁显福; 等
（1.安徽医科大学附属巢湖医院麻醉科，安徽 巢湖 238000）（2.安徽医科大学第一附属医院麻醉科，安徽 合肥 230022）
Author(s):
LIU Tong-hao; LI Yuan-hai; LU Xian-fu; et al.
(1.Department of Anesthesia,Chaohu Hospital of Anhui Medical University,Chaohu 238000,Anhui,China;2.Department of Anesthesia,the First Affiliated Hospital of Anhui Medical University,Chaohu 238000,Anhui,China)
关键词:
食管癌; 麻醉; 硬膜外镇痛; 胸腔积液
Keywords:
Esophageal cancer; Anesthesia; Epidural analgesia; Pleural effusion
分类号:
R735.1
DOI:
10.3969/j.issn.1006-1959.2023.22.014
文献标志码:
A
摘要:
目的 分析食管癌患者术后胸腔积液的发生情况及危险因素。方法 回顾性分析2017年1月-2019年12月于安徽医科大学第一附属医院行食管癌根治术的444例食管鳞癌患者的临床病理资料，采用单因素和多因素回归分析患者术后发生胸腔积液的危险因素。结果 444例患者中208例存在胸腔积液；单因素分析显示，患者术后发生胸腔积液与术前美国麻醉医师协会风险分级、心律失常、术前肺大疱、联合硬膜外麻醉、硬膜外用药类型、硬膜外用药量、舒芬太尼用量、使用胶体、镇痛泵、合并肺炎、淋巴结转移是否大于2枚及术后低蛋白有关（P＜0.05）；多因素分析显示，术后硬膜外吗啡镇痛、术中舒芬太尼用量大、术中维库溴铵用量大、术中晶体补液量多、术前存在心律失常、术后低蛋白、术后合并肺炎、术前淋巴结转移大于2枚是食管癌术后发生胸腔积液的独立危险因素（P＜0.05）。结论 术后是否使用硬膜外吗啡镇痛、术中舒芬太尼用量、术中维库溴铵用量、术中晶体补液量、术前是否存在心律失常、术后是否低蛋白、术后是否合并肺炎级淋巴结转移情况与食管癌患者术后胸腔积液的发生密切相关。
Abstract:
Objective To analyze the incidence and risk factors of postoperative pleural effusion in patients with esophageal cancer.Methods The clinicopathological data of 444 patients with esophageal squamous cell carcinoma who underwent radical resection of esophageal cancer in the First Affiliated Hospital of Anhui Medical University from January 2017 to December 2019 were retrospectively analyzed. Univariate and multivariate regression analysis were used to analyze the risk factors of postoperative pleural effusion.Results Pleural effusion was found in 208 of 444 patients. Univariate analysis showed that postoperative pleural effusion was associated with preoperative American Society of Anesthesiologists risk classification, arrhythmia, preoperative pulmonary bullae, combined epidural anesthesia, epidural medication type, epidural dosage, sufentanil dosage, use of colloid, analgesia pump, combined pneumonia, lymph node metastasis greater than 2 and postoperative low protein (P<0.05). Multivariate analysis showed that postoperative epidural morphine analgesia, intraoperative sufentanil dosage, intraoperative vecuronium dosage, intraoperative crystal fluid volume, preoperative arrhythmia, postoperative low protein, postoperative pneumonia, preoperative lymph node metastasis greater than 2 were independent risk factors for pleural effusion after esophageal cancer surgery (P<0.05).Conclusion Postoperative epidural morphine analgesia, intraoperative sufentanil dosage, intraoperative vecuronium dosage, intraoperative crystal rehydration volume, preoperative arrhythmia, postoperative low protein, and postoperative pneumonia lymph node metastasis are closely related to the occurrence of postoperative pleural effusion in patients with esophageal cancer.

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更新日期/Last Update: 1900-01-01