[1]吴 丹.卡前列素氨丁三醇、麦角新碱、缩宫素三联疗法对阴道分娩产妇产后出血及子宫复旧的影响[J].医学信息,2024,37(15):107-110.[doi:10.3969/j.issn.1006-1959.2024.15.024]
　WU Dan.Effect of Triple Therapy of Carboprost Tromethamine, Ergometrine and Oxytocin on Postpartum Hemorrhage and Uterine Involution in Vaginal Delivery Women[J].Journal of Medical Information,2024,37(15):107-110.[doi:10.3969/j.issn.1006-1959.2024.15.024]
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卡前列素氨丁三醇、麦角新碱、缩宫素三联疗法对阴道分娩产妇产后出血及子宫复旧的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年15期
页码:
107-110
栏目:
论著
出版日期:
2024-08-01

文章信息/Info

Title:
Effect of Triple Therapy of Carboprost Tromethamine, Ergometrine and Oxytocin on Postpartum Hemorrhage and Uterine Involution in Vaginal Delivery Women
文章编号:
1006-1959（2024）15-0107-04
作者:
吴 丹
（天津港口医院妇产科，天津 300456）
Author(s):
WU Dan
(Department of Obstetrics and Gynecology,Tianjin Port Hospital,Tianjin 300456,China)
关键词:
阴道分娩; 产后出血; 卡前列素氨丁三醇; 麦角新碱; 缩宫素; 子宫复旧
Keywords:
Vaginal delivery; Postpartum hemorrhage; Carboprost tromethamine; Ergometrine; Oxytocin; Uterine involution
分类号:
R714.46+1
DOI:
10.3969/j.issn.1006-1959.2024.15.024
文献标志码:
A
摘要:
目的 研究卡前列素氨丁三醇（CTI）、麦角新碱（EM）、缩宫素（OT）三联疗法对阴道分娩产妇产后出血及子宫复旧的影响。方法 以2020年6月-2023年6月天津港口医院拟行阴道分娩的80例产妇为研究对象，经随机数字表法分为对照组与观察组，各40例。对照组给予EM联合OT治疗，观察组则应用CTI、EM、OT三联疗法，比较两组用药效果、产后出血量（术后2 h出血量、术后24 h出血量）、生化指标[血红蛋白（Hb）、产后Hb下降≥30 g/L占比]、不良反应（消化道症状、头晕、心悸、血压异常）、子宫复旧情况（宫底下降速度、恶露持续时间）。结果 观察组用药有效率高于对照组，术后2、24 h出血量均少于对照组（P＜0.05）；产后24 h，两组Hb水平低于产前，差异无统计学意义（P＞0.05）；观察组产后Hb下降≥30 g/L占比小于对照组（P＜0.05）；两组不良反应发生率比较，差异无统计学意义（P＞0.05）；观察组宫底下降速度大于对照组，且恶露持续时间短于对照组（P＜0.05）。结论 CTI、EM、OT三联疗法对阴道分娩产妇产后出血具有良好预防效果，可降低其产后出血量，减少Hb流失，加速子宫复旧，且具有较高用药安全性。
Abstract:
Objective To study the effect of triple therapy of carboprost tromethamine (CTI), ergometrine (EM) and oxytocin (OT) on postpartum hemorrhage and uterine involution in vaginal delivery.Methods From June 2020 to June 2023, 80 puerperaes who underwent vaginal delivery in Tianjin Port Hospital were selected as the research objects. They were divided into control group and observation group by random number table method, with 40 puerperaes in each group. The control group was treated with EM combined with OT, while the observation group was treated with triple therapy of CTI, EM and OT. The medication effect, postpartum hemorrhage (2 h after operation, 24 h after operation), biochemical indexes [hemoglobin (Hb), proportion of postpartum Hb decrease≥30 g/L], adverse reactions (gastrointestinal symptoms, dizziness, palpitations, abnormal blood pressure), uterine involution (fundus descent speed, lochia duration) were compared between the two groups.Results The effective rate of the observation group was higher than that of the control group, and the amount of bleeding at 2 and 24 h after operation was less than that of the control group (P<0.05). The proportion of postpartum Hb decrease ≥30 g/L in the observation group was lower than that in the control group (P<0.05). The rate of fundus descent in the observation group was higher than that in the control group, and the duration of lochia was shorter than that in the control group (P<0.05).Conclusion Triple therapy of CTI, EM and OT has a good preventive effect on postpartum hemorrhage in vaginal delivery women, which can reduce the amount of postpartum hemorrhage, reduce Hb loss, accelerate uterine involution, and has high medication safety.

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更新日期/Last Update: 1900-01-01