[1]徐 凡.平喘固本汤和补肺汤加减联合头孢他啶和左氧氟沙星治疗老年慢阻肺的临床效果及对其血清学指标的影响[J].医学信息,2025,38(11):150-153.[doi:10.3969/j.issn.1006-1959.2025.11.031]
　XU Fan.Clinical Effect of Modified Pingchuan Guben Decoction and Bufei Decoction Combined with Ceftazidime and Levofloxacin in the Treatment of Elderly Patients with Chronic Obstructive Pulmonary Disease and its Influence on Serological Indexes[J].Journal of Medical Information,2025,38(11):150-153.[doi:10.3969/j.issn.1006-1959.2025.11.031]
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平喘固本汤和补肺汤加减联合头孢他啶和左氧氟沙星治疗老年慢阻肺的临床效果及对其血清学指标的影响()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年11期
页码:
150-153
栏目:
药物与临床
出版日期:
2025-06-01

文章信息/Info

Title:
Clinical Effect of Modified Pingchuan Guben Decoction and Bufei Decoction Combined with Ceftazidime and Levofloxacin in the Treatment of Elderly Patients with Chronic Obstructive Pulmonary Disease and its Influence on Serological Indexes
文章编号:
1006-1959（2025）11-0150-04
作者:
徐 凡
抚州市东乡区中医院内二科，江西 抚州 33180
Author(s):
XU Fan
The Second Department of Internal Medicine, Dongxiang District Hospital of Traditional Chinese Medicine, Fuzhou 331800, Jiangxi, China
关键词:
慢阻肺; 老年患者; 平喘固本汤; 补肺汤; 头孢他啶; 左氧氟沙星; 血清学指标; 肺功能
Keywords:
Chronic obstructive pulmonary disease;  Elderly patients;  Pingchuan Guben decoction;  Bufei decoction;  Ceftazidime;  Levofloxacin;  Serological indexes;  Pulmonary function
分类号:
R563.9
DOI:
10.3969/j.issn.1006-1959.2025.11.031
文献标志码:
A
摘要:
目的 研究平喘固本汤和补肺汤加减联合头孢他啶和左氧氟沙星治疗老年慢阻肺（COPD）的临床效果及对其血清学指标的影响。方法 以2021年1月-2023年12月抚州市东乡中医院内二科收治的50例老年COPD患者为研究对象，经抽签法分为西医组（25例）与中西医结合组（25例），两组均接受常规对症治疗。西医组给予头孢他啶+左氧氟沙星治疗，中西医结合组在其基础上加用平喘固本汤和补肺汤加减治疗，比较两组临床效果、血清学指标[C反应蛋白（CRP）、白细胞计数（WBC）]、肺功能[用力肺活量（FVC）、第1秒用力呼气容积（FEV1）]、COPD患者自我评估测（CAT）评分、圣乔治呼吸问卷（SGRQ）评分。结果 中西医结合组临床改善率高于西医组（P＜0.05）；两组治疗后CRP、WBC指标低于治疗前，且中西医结合组CRP、WBC指标低于西医组（P＜0.05）；两组治疗后FVC、FEV1高于治疗前，且中西医结合组FVC、FEV1高于西医组（P＜0.05）；两组治疗后CAT、SGRQ评分低于治疗前，且中西医结合组CAT、SGRQ评分低于西医组（P＜0.05）。结论 平喘固本汤和补肺汤加减联合头孢他啶和左氧氟沙星在老年COPD患者中具有良好治疗效果，可下调其血清炎性指标，改善患者肺功能，减轻其呼吸道症状。
Abstract:
Objective To study the clinical effect of modified Pingchuan Guben decoction and Bufei decoction combined with ceftazidime and levofloxacin in the treatment of elderly patients with chronic obstructive pulmonary disease (COPD) and its effect on serological indexes. Methods A total of 50 elderly patients with COPD admitted to the Second Department of Internal Medicine of Fuzhou Dongxiang Hospital of Traditional Chinese Medicine from January 2021 to December 2023 were selected as the research objects. They were divided into western medicine group (25 patients) and integrated traditional Chinese and western medicine group (25 patients) by drawing lots. Both groups received routine symptomatic treatment. The western medicine group was treated with ceftazidime+levofloxacin, and the integrated Chinese and western medicine group was treated with modified Pingchuan Guben decoction and Bufei decoction on the basis of the western medicine group. The clinical effects, serological indexes [C-reactive protein (CRP), white blood cell count (WBC)], lung function [forced vital capacity (FVC), forced expiratory volume in one second (FEV1)], COPD assessment test (CAT) score, and St.George’s Respiratory Questionnaire (SGRQ) score were compared between the two groups. Results The clinical improvement rate of the integrated traditional Chinese and western medicine group was higher than that of the western medicine group (P<0.05). The CRP and WBC indexes of the two groups after treatment were lower than those before treatment, and the CRP and WBC indexes of the integrated traditional Chinese and western medicine group were lower than those of the western medicine group (P<0.05). After treatment, FVC and FEV1 in the two groups were higher than those before treatment, and FVC and FEV1 in the integrated traditional Chinese and western medicine group were higher than those in the western medicine group (P<0.05). The CAT and SGRQ scores of the two groups after treatment were lower than those before treatment, and the CAT and SGRQ scores of the integrated traditional Chinese and western medicine group were lower than those of the western medicine group (P<0.05). Conclusion Modified Pingchuan Guben decoction and Bufei decoction combined with ceftazidime and levofloxacin have a good therapeutic effect in elderly patients with COPD, which can down-regulate their serum inflammatory indicators, improve the lung function, and reduce the respiratory symptoms.

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更新日期/Last Update: 1900-01-01