[1]王文庆.手法复位微创PFNA内固定治疗老年股骨粗隆间骨折的有效性及对血清NE、AngⅡ水平的影响[J].医学信息,2025,38(19):121-124,129.[doi:10.3969/j.issn.1006-1959.2025.19.025]
　WANG Wenqing.Efficacy of Manual Reduction and Minimally Invasive PFNA Internal Fixation in the Treatment of Intertrochanteric Fractures in the Elderly and its Effect on Serum NE and Ang Ⅱ Levels[J].Journal of Medical Information,2025,38(19):121-124,129.[doi:10.3969/j.issn.1006-1959.2025.19.025]
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手法复位微创PFNA内固定治疗老年股骨粗隆间骨折的有效性及对血清NE、AngⅡ水平的影响()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年19期
页码:
121-124,129
栏目:
论著
出版日期:
2025-10-01

文章信息/Info

Title:
Efficacy of Manual Reduction and Minimally Invasive PFNA Internal Fixation in the Treatment of Intertrochanteric Fractures in the Elderly and its Effect on Serum NE and Ang Ⅱ Levels
文章编号:
1006-1959（2025）19-0121-05
作者:
王文庆
天津市滨海新区大港医院骨二科，天津 300270
Author(s):
WANG Wenqing
The Second Department of Orthopedics, Dagang Hospital, Binhai New Area, Tianjin 300270, China
关键词:
手法复位; 微创PFNA内固定; 老年股骨粗隆间骨折; 应激反应
Keywords:
Manual reduction;  Minimally invasive PFNA internal fixation;  Intertrochanteric fractures in the elderly;  Stress response
分类号:
R687.3
DOI:
10.3969/j.issn.1006-1959.2025.19.025
文献标志码:
A
摘要:
目的 分析手法复位微创PFNA内固定治疗老年股骨粗隆间骨折的有效性及对血清NE、AngⅡ水平的影响。方法 选择2018年7月-2023年12月在天津市滨海新区大港医院接受手术治疗的老年股骨粗隆间骨折患者276例作为观察对象，按随机数字表法划分成研究组和对照组，每组138例。对照组应用牵引床闭合复位PFNA内固定治疗，研究组应用手法牵引闭合复位微创PFNA内固定治疗。比较两组临床疗效、手术情况（手术时间、术中出血量、负重行走的时间、骨折愈合的时间、住院时间、卧床时间）、不同时间点髋关节功能评分、应激反应水平[醛固酮（ALD）、血管紧张素Ⅱ（AngⅡ）、去甲肾上腺素（NE）]。结果 研究组治疗总有效率高于对照组（P＜0.05）。研究组手术情况均优于对照组（P＜0.05）。研究组患者不同时间点髋关节功能评分均高于对照组（P＜0.05）。与术前比较，两组术后应激反应指标水平均升高，但与对照组比较，研究组应激反应指标水平更低（P＜0.05）。结论 手法复位微创PFNA内固定治疗老年股骨粗隆间骨折的临床疗效确切，能够改善患者预后情况，提高患者髋关节功能，减轻患者手术应激反应，值得临床推广应用。
Abstract:
Objective To analyze the effectiveness of manual reduction and minimally invasive PFNA internal fixation in the treatment of intertrochanteric fractures in the elderly and its effect on serum NE and Ang Ⅱ levels. Methods A total of 276 elderly patients with intertrochanteric fractures who underwent surgical treatment in Dagang Hospital of Tianjin Binhai New Area from July 2018 to December 2023 were selected as observation objects. They were divided into study group and control group according to random number table method, 138 patients per each group. The control group was treated with traction bed closed reduction and PFNA internal fixation, and the study group was treated with manual traction closed reduction and minimally invasive PFNA internal fixation. The clinical efficacy, surgical conditions (operation time, intraoperative blood loss, weight-bearing walking time, fracture healing time, hospitalization time, bed rest time), hip function scores at different time points, and stress response levels [aldosterone (ALD), angiotensin Ⅱ (AngⅡ), norepinephrine (NE)] were compared between the two groups. Results The total effective rate of treatment in the study group was higher than that in the control group (P<0.05). The operation of the study group was better than that of the control group (P<0.05). The score of hip joint function at different time points in the study group was higher than that in the control group (P<0.05). Compared with before operation, the levels of stress response indexes in the two groups increased after operation, but compared with the control group, the levels of stress response indexes in the study group were lower (P<0.05). Conclusion Manual reduction and minimally invasive PFNA internal fixation has a definite clinical effect in the treatment of intertrochanteric fractures in the elderly, which can improve the prognosis of patients, improve their hip function, and reduce the surgical stress response. It is worthy of clinical application.

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更新日期/Last Update: 1900-01-01