[1]杨鹏华.血府逐瘀汤加减对冠心病患者中医证候及心功能指标的影响[J].医学信息,2025,38(24):137-141.[doi:10.3969/j.issn.1006-1959.2025.24.028]
　YANG Penghua.Effect of Modified Xuefu Zhuyu Decoction on TCM Syndromes and Cardiac FunctionIndexes in Patients with Coronary Heart Disease[J].Journal of Medical Information,2025,38(24):137-141.[doi:10.3969/j.issn.1006-1959.2025.24.028]
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血府逐瘀汤加减对冠心病患者中医证候及心功能指标的影响()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年24期
页码:
137-141
栏目:
论著
出版日期:
2025-12-15

文章信息/Info

Title:
Effect of Modified Xuefu Zhuyu Decoction on TCM Syndromes and Cardiac FunctionIndexes in Patients with Coronary Heart Disease
文章编号:
1006-1959（2025）24-0137-05
作者:
杨鹏华
庆阳市人民医院中医科，甘肃 庆阳 745000
Author(s):
YANG Penghua
Department of Traditional Chinese Medicine, Qingyang People′s Hospital, Qingyang 745000, Gansu, China
关键词:
血府逐瘀汤加减; 冠心病; 气滞血瘀证; 心功能; 血液流变学
Keywords:
Modified Xuefu Zhuyu decoction;  Coronary heart disease;  Syndrome of qi stagnation and blood stasis;  Cardiac function;  Hemorheology
分类号:
R541.4
DOI:
10.3969/j.issn.1006-1959.2025.24.028
文献标志码:
A
摘要:
目的 分析血府逐瘀汤加减对冠心病患者中医证候及心功能指标的影响。方法 选取2022年6月-2025年5月庆阳市人民医院收治的300例气滞血瘀证冠心病患者，通过随机数字表法分为对照组（150例）和研究组（150例）。对照组实施常规西医治疗方案，研究组在常规治疗基础上加用血府逐瘀汤加减治疗。观察两组临床疗效、中医症状评分（胸部刺痛、心悸、胸闷）、心功能参数[左室射血分数（LVEF）、心输出量（CO）、每搏输出量（SV）]及血液流变学指标（全血高切黏度、红细胞变形指数、血浆黏度、纤维蛋白原）。结果 研究组临床总有效率达93.33%，优于对照组的77.33%（P＜0.05）。治疗后两组胸部刺痛、心悸、胸闷评分均下降，且研究组各项评分下降幅更大（P＜0.05）。治疗后两组LVEF、CO、SV均提升，且研究组改善程度更优（P＜0.05）。治疗后研究组全血高切黏度、血浆黏度、纤维蛋白原水平低于对照组，红细胞变形指数水平高于对照组（P＜0.05）。结论 血府逐瘀汤加减联合常规西医疗法可提升冠心病（气滞血瘀证）患者的临床疗效，有效缓解临床症状，改善心脏功能，调节血液流变学状态，治疗安全性良好。
Abstract:
Objective To analyze the effect of modified Xuefu Zhuyu decoction on TCM syndromes and cardiac function indexes in patients with coronary heart disease. Methods A total of 300 coronary heart disease patients with syndrome of qi stagnation and blood stasis admitted to Qingyang People′s Hospital from June 2022 to May 2025 were selected and divided into control group (150 patients) and study group (150 patients) by random number table method. The control group was treated with conventional western medicine treatment, and the study group was treated with modified Xuefu Zhuyu decoction on the basis of conventional treatment. The clinical efficacy, TCM symptom scores (chest tingling, palpitation, oppression in chest), cardiac function parameters [left ventricular ejection fraction (LVEF), cardiac output (CO), stroke volume (SV)] and hemorheology indexes (whole blood high shear viscosity, erythrocyte deformation index, plasma viscosity, fibrinogen) were observed in the two groups. Results The total clinical effective rate of the study group was 93.33%, which was better than 77.33% of the control group (P<0.05). After treatment, the scores of chest tingling, palpitation and oppression in chest in the two groups decreased, and the scores in the study group were decreased more significantly (P<0.05). After treatment, the LVEF, CO and SV of the two groups increased, and the improvement of the study group was better (P<0.05). After treatment, the levels of whole blood high shear viscosity, plasma viscosity and fibrinogen in the study group were lower than those in the control group, and the level of erythrocyte deformation index was higher than that in the control group (P<0.05). Conclusion Modified Xuefu Zhuyu Decoction combined with conventional western medicine therapy can improve the clinical efficacy of patients with coronary heart disease (syndrome of qi stagnation and blood stasis), effectively relieve clinical symptoms, improve cardiac function, regulate hemorheology, and have good treatment safety.

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更新日期/Last Update: 1900-01-01