[1]袁雁平.细菌定量计数联合尿沉渣白细胞检验在尿路感染诊断中的应用价值[J].医学信息,2026,39(04):162-165.[doi:10.3969/j.issn.1006-1959.2026.04.030]
 YUAN Yanping.Application Value of Bacterial Quantitative Count Combined with Urine Sediment White BloodCell Test in the Diagnosis of Urinary Tract Infection[J].Journal of Medical Information,2026,39(04):162-165.[doi:10.3969/j.issn.1006-1959.2026.04.030]
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细菌定量计数联合尿沉渣白细胞检验在尿路感染诊断中的应用价值()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
39卷
期数:
2026年04期
页码:
162-165
栏目:
临床证据信息
出版日期:
2026-02-15

文章信息/Info

Title:
Application Value of Bacterial Quantitative Count Combined with Urine Sediment White BloodCell Test in the Diagnosis of Urinary Tract Infection
文章编号:
1006-1959(2026)04-0162-04
作者:
袁雁平
天津市河西区妇产科医院,天津 300202
Author(s):
YUAN Yanping
Tianjin Hexi District Maternity and Children′s Hospital, Tianjin 300202, China
关键词:
尿路感染细菌定量计数尿沉渣白细胞检验
Keywords:
Urinary tract infection Bacterial quantitative count Urinary sediment white blood cell test
分类号:
R446.5
DOI:
10.3969/j.issn.1006-1959.2026.04.030
文献标志码:
A
摘要:
目的 观察在尿路感染诊断中应用细菌定量计数联合尿沉渣白细胞检验的价值。方法 选取2024年6月-10月于本院就诊的100例尿路感染疑似患者作为观察对象。所有病例均同步接受细菌定量计数与尿沉渣白细胞检测。研究以尿液细菌培养结果为参照标准,并对培养结果进行统计分析。此外,对不同检验方法阳性率和诊断效能、不同检测方法对尿路感染诊断准确率与尿细菌培养结果的一致性进行分析,并采用ROC曲线分析不同检验方法对尿路感染诊断。结果 尿细菌培养结果显示,100例样本检出阳性83例,阳性率为83.00%,主要病原菌为大肠埃希菌,其次为链球菌、葡萄球菌;联用细菌定量计数与尿沉渣白细胞检查的阳性检出率为81.00%,高于单一细菌定量计数(74.00%)或单纯尿沉渣白细胞检验(69.00%)(P<0.05),而单独两种方法的阳性率无差异(P>0.05);在诊断效能(包括敏感度、特异度、阳性和阴性预测值)方面,相比单一检测,联合应用细菌定量计数与尿沉渣白细胞检验更具优势(P<0.05);细菌定量计数+尿沉渣白细胞检验与尿培养结果具有一致性;ROC曲线分析结果显示,尿沉渣白细胞检验的AUC为0.847,细菌定量计数为0.892,二者联合检验的AUC为0.965。结论 尿路感染诊断中,细菌定量计数与尿沉渣白细胞联检在敏感度与特异度方面均表现出良好性能,同时与尿细菌培养一致性较高。
Abstract:
Objective To observe the application value of quantitative bacterial count combined with urinary sediment white blood cell test in the diagnosis of urinary tract infection. Methods A total of 100 patients with suspected urinary tract infection who were treated in our hospital from June to October 2024 were selected as observation objects. All cases received simultaneous bacterial quantitative count and urine sediment white blood cell detection. The results of urine bacterial culture were used as the reference standard, and the results were statistically analyzed. In addition, the positive rate and diagnostic efficiency of different test methods, the consistency between the diagnostic accuracy of different test methods for urinary tract infection and the results of urine bacterial culture were analyzed, and the ROC curve was used to analyze the diagnosis of urinary tract infection by different test methods. Results The results of urine bacterial culture showed that 83 cases were positive in 100 samples, with a positive rate of 83.00%. The main pathogenic bacteria were Escherichia coli, followed by Streptococcus and Staphylococcus. The positive rate of bacterial quantitative count+urine sediment white blood cell detection was 81.00%, which was higher than 74.00% of bacterial quantitative count and 69.00% of urine sediment white blood cell test (P<0.05), however, no statistically significant difference was observed in the positive rates of the two methods (P>0.05). Compared with single detection, the combined application of bacterial quantitative count and urinary sediment white blood cell test showed advantages in various diagnostic efficacy indexes (including sensitivity, specificity, positive and negative predictive values), and the difference was statistically significant (P<0.05). The results of bacterial quantitative count+urine sediment white blood cell test were consistent with those of urine culture. ROC analysis revealed that the AUC for urinary sediment WBC count was 0.847, for bacterial quantitative count was 0.892, and for the combined test reached 0.965. Conclusion In the diagnosis of urinary tract infection, the combined detection of bacterial quantitative count and urinary sediment white blood cell has good performance in sensitivity and specificity, and has high consistency with urinary bacterial culture.

参考文献/References:

[1]裴倩倩,高云,王春梅.中性粒细胞与淋巴细胞比值辅助诊断老年社区获得性尿路感染的研究[J].中华全科医学,2024,8(7):81-83.[2]王文娟,张瑜,王凯.在尿常规临床检验中应用分析前质量控制措施的临床效果[J].实用检验医师杂志,2023,15(2):155-158.[3]陈文青,聂力平.不同检测方法联合检测对尿路感染的诊断价值[J].慢性病学杂志,2024,25(2):286-288.[4]陈王超,张新军.白蛋白与球蛋白比率在输尿管镜碎石术后并发发热性尿路感染早期诊断中的价值[J].现代临床医学,2024,24(7):51-54.[5]杨铭理,陈瑞英.尿液定量分析参数和尿常规白细胞酯酶检测在尿路感染中的临床意义[J].江西医药,2022,57(10):1562-1564,1571.[6]吴绍辉.细菌定量计数结合尿沉渣白细胞检测与尿细菌培养诊断尿路感染的比较研究[J].临床检验杂志(电子版),2017,6(4):655-656.[7]陶炜,刘万宗,董小康,等.US-BACT、US-WBC及BWBC在诊断细菌性尿路感染中的应用[J].分子诊断与治疗杂志,2021,13(4):543-546. [8]瞿易,唐友东.尿白细胞、细菌及亚硝酸盐联合检测在尿路感染诊断中的应用价值[J].包头医学院学报,2020,34(1):73-74.[9]吴亚丽.尿常规亚硝酸盐白细胞酯酶检测和细菌计数对尿路感染的诊断价值[J].山西医药杂志,2021,50(14):2212-2213.[10]陈运娇,罗标,陆居文,等.细菌培养与尿沉渣细菌定量分析在尿路感染诊断价值对比分析[J].黑龙江医药,2019,32(5):1223-1224.[11]周先明,疏仁义,李建.血清炎症指标对老年BPH患者术后尿路感染的预测价值[J].中国老年学杂志,2021,41(15):3227-3230.[12]时翠销,王刚,李亚娟,等.尿路感染B群链球菌的耐药特征与CAMP试验敏感性分析[J].安徽医科大学学报,2021,56(10):1516-1520.[13]杜颖,冯景,杨传信,等.尿常规及尿液定量分析参数在早期尿路感染经验性用药中的应用[J].检验医学,2020,35(10):1046-1048.[14]彭皎.细菌定量计数联合尿沉渣白细胞检验在尿路感染诊断中的应用价值分析[J].现代诊断与治疗,2020,31(8):1179-1181.[15]梅方超,戴海英,尚小玲,等.尿液HBP,LE,U-NIT和WBC联合检测与尿液细菌定量培养对急性尿道感染的诊断意义[J].现代检验医学杂志,2018,33(5):126-128.[16]陈曼娜,林少荣,张俊钿.尿十联检验联合细菌定量检测在尿路感染诊断中的应用价值分析[J].中国医学工程,2021,29(2):82-85.[17]纪凤卿,刘伟民,陈君颖,等.UN2000尿液全自动化流水线系统和中段尿培养检测在尿路感染诊断中的应用[J].检验医学与临床,2021,18(23):3468-3471.[18]付晓峰.尿β2-MG、WBC水平检测对尿路感染的诊断价值分析[J].辽宁医学杂志,2022,36(4):81-83.[19]赵莹.尿干化学法联合尿沉渣法用于尿液检验的临床效果观察[J].中国基层医药,2020,27(7):776-780.[20]魏颖.细菌定量计数结合尿白细胞检测在尿路感染中的应用[J].西藏医药,2020,41(1):27-28.[21]李果,张驰,黄铭,等.UF-1000i自动尿液分析仪对尿路感染的诊断价值[J].实验与检验医学,2021,39(1):70-71,117.[22]房宇.细菌定量计数联合尿沉渣白细胞检验在尿路感染诊断中的应用价值[J].系统医学,2022,7(10):72-75.

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更新日期/Last Update: 1900-01-01