[1]朱津津.Hcy、BNP检测在2型糖尿病肾病早期诊断中的价值分析[J].医学信息,2018,31(03):163-164.[doi:10.3969/j.issn.1006-1959.2018.03.060]
　ZHU Jin-jin.The Value of Hcy and BNP in the Early Diagnosis of Type 2 Diabetic Nephropathy[J].Journal of Medical Information,2018,31(03):163-164.[doi:10.3969/j.issn.1006-1959.2018.03.060]
点击复制

Hcy、BNP检测在2型糖尿病肾病早期诊断中的价值分析()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年03期
页码:
163-164
栏目:
诊疗技术
出版日期:
2018-02-01

文章信息/Info

Title:
The Value of Hcy and BNP in the Early Diagnosis of Type 2 Diabetic Nephropathy
文章编号:
1006-1959（2018）03-0163-02
作者:
朱津津
天津市武清区中医医院检验科，天津 300000
Author(s):
ZHU Jin-jin
Department of Laboratory Medicine,Wuqing District Traditional Chinese Medicine Hospital,Tianjin 300000,China
关键词:
2型糖尿病肾病; BNP; Hcy; 早期诊断
Keywords:
Type 2 diabetic nephropathy; BNP; Hcy; Early diagnosis
分类号:
R714.22
DOI:
10.3969/j.issn.1006-1959.2018.03.060
文献标志码:
A
摘要:
目的 分析Hcy和BNP联合检测在2型糖尿病肾病早期诊断中的价值。方法 选取2015年6月~2017年6月我院收治的2型糖尿病患者60例作为研究对象，依据尿蛋白排泄率分为A组（n=20，正常蛋白尿组）、B组（n=20，微量蛋白尿组）、C组（n=20，临床蛋白尿组），选择健康体检者20例作为对照组，对四组血浆Hcy、BNP及Cys-C、UmALB、Scr进行检测，并对检测结果进行比较。结果 UmALB无论被定性为阴性或阳性，A、B、C 三组的Hcy、BNP、Cys-C、Scr均显著高于对照组，差异有统计学意义（P＜0.05）；UmALB被定性为阳性时，B组、C组的Hcy、BNP、Cys-C、Scr高于A组，组间比较，C组高于B组，差异有统计学意义（P＜0.05）。结论 Hcy和BNP与UmALB均存在密切关系，二者联合检测具有较高的诊断准确率，可对2型糖尿病肾病的损害程度进行推断，具有较高的早期诊断价值。
Abstract:
Objective To analyze the value of combined detection of Hcy and BNP in the early diagnosis of type 2 diabetic nephropathy.Methods 60 patients with type 2 diabetes mellitus admitted to our hospital from June 2015 to June 2017 were divided into group A(n=20,normal proteinuria group)and group B(n=20,microalbuminuria group),C group(n=20,clinical proteinuria group),20 healthy subjects were selected as the control group,plasma Hcy,BNP and Cys-C,UmALB and Scr were detected in the four groups.The test results were compared.Results Whether UmALB was negative or positive,the levels of Hcy, BNP, Cys-C and Scr in group A,B and C were significantly higher than those in control group(P<0.05);When UmALB was positive, the levels of Hcy,BNP,Cys-C and Scr in group B and group C were higher than those in group A,compared between groups,C group was higher than B group,the difference was statistically significant(P<0.05).Conclusion Hcy and BNP are closely related to UmALB.The combined detection of Hcy and BNP has high diagnostic accuracy,which can be used to infer the degree of damage of type 2 diabetic nephropathy,which has high diagnostic value in early stage.

参考文献/References:

[1]林少荣,陈龙峰,陈曼娜,等.同型半胱氨酸和脑钠肽联合检测对糖尿病肾病的早期诊断价值[J].广东医学,2015,36(15):2366-2368.
[2]曹俊娟,许香梅,卢彩平,等.血清 CysC、HCY 联合 BNP、hs-CRP 检测对早期糖尿病肾损害的诊断价值[J].河北医药,2015,58(22):3385-3388.
[3]周纪良.血清Hcy与BNP对糖尿病肾病的早期诊断效果[J].检验医学与临床,2016,13(18):2660-2661.
[4]曹俊娟,许香梅,卢彩平,等.血清 BNP、HCY、cTnI 和 hs-CRP 对预测糖尿病肾病并发心血管病变的临床价值[J].河北医药,2015,36(20):3094-3096.

相似文献/References:

[1]郭俊林,张立.BNP对CRT后期疗效的临床评价[J].医学信息,2018,31(01):67.[doi:10.3969/j.issn.1006-1959.2018.01.024]
　GUO Jun-lin,ZHANG li.Clinical Evaluation of BNP in Treatment of Late CRT[J].Journal of Medical Information,2018,31(03):67.[doi:10.3969/j.issn.1006-1959.2018.01.024]
[2]毛红岩,宁国贤.冠脉介入治疗对冠心病急性心肌梗死患者 心肌损伤及心室重塑的影响[J].医学信息,2018,31(12):102.[doi:10.3969/j.issn.1006-1959.2018.12.031]
　MAO Hong-yan,NING Guo-xian.Effects of Coronary Intervention on Myocardial Injury and Ventricular Remodeling in Patients with Coronary Heart Disease and Acute Myocardial Infarction[J].Journal of Medical Information,2018,31(03):102.[doi:10.3969/j.issn.1006-1959.2018.12.031]
[3]黄秉文.中美两种2型糖尿病肾病诊断标准中疾病进展及预后因素对比[J].医学信息,2018,31(22):68.[doi:10.3969/j.issn.1006-1959.2018.22.019]
　HUANG Bing-wen.Comparison of Disease Progression and Prognostic Factors in Two Diagnostic Criteria for Type 2 Diabetic Nephropathy in China and the United States[J].Journal of Medical Information,2018,31(03):68.[doi:10.3969/j.issn.1006-1959.2018.22.019]
[4]赵海莲.血尿酸水平与2型糖尿病肾病患者肾脏损害的相关性分析[J].医学信息,2020,33(06):93.[doi:10.3969/j.issn.1006-1959.2020.06.027]
　ZHAO Hai-lian.Correlation Between Serum Uric Acid Level and Renal Damage in Patients with Type 2 Diabetic Nephropathy[J].Journal of Medical Information,2020,33(03):93.[doi:10.3969/j.issn.1006-1959.2020.06.027]
[5]段宗宝,肖三法,罗惠群.环磷酰胺联合氢氯噻嗪治疗2型糖尿病肾病的临床研究[J].医学信息,2021,34(23):159.[doi:10.3969/j.issn.1006-1959.2021.23.048]
　DUAN Zong-bao,XIAO San-fa,LUO Hui-qun.Clinical Study of Cyclophosphamide Combined with Hydrochlorothiazide in the Treatment of Type 2 Diabetic Nephropathy[J].Journal of Medical Information,2021,34(03):159.[doi:10.3969/j.issn.1006-1959.2021.23.048]
[6]阎 丽,宋 迎.甲状腺激素与不同阶段2型糖尿病肾病的相关性研究[J].医学信息,2022,35(19):155.[doi:10.3969/j.issn.1006-1959.2022.19.045]
　YAN Li,SONG Ying.Study on the Correlation Between Thyroid Hormone and Different Stages of Type 2 Diabetic Nephropathy[J].Journal of Medical Information,2022,35(03):155.[doi:10.3969/j.issn.1006-1959.2022.19.045]
[7]付彩雯,吴 艳.FGF23/Klotho在2型糖尿病肾病和骨质疏松共病中的研究现状[J].医学信息,2024,37(03):176.[doi:10.3969/j.issn.1006-1959.2024.03.037]
　FU Cai-wen,WU Yan.Research Status of FGF23/Klotho in the co-morbidities of Type 2 Diabetic Nephropathy and Osteoporosis[J].Journal of Medical Information,2024,37(03):176.[doi:10.3969/j.issn.1006-1959.2024.03.037]

更新日期/Last Update: 2018-02-01