[1]傅锡霖,陈俊鸿,季坚卫.布拉氏酵母菌联合葡萄糖酸锌防治婴幼儿抗生素相关性腹泻临床效果观察[J].医学信息,2018,31(06):115-116.[doi:10.3969/j.issn.1006-1959.2018.06.038]
　FU Xi-lin,CHEN Jun-hong,JI Jian-wei.Clinical Effect of Saccharomyces Brassicus Combined with Zinc Gluconate on the Prevention and Treatment of Antibiotic Associated Diarrhea in Infants[J].Journal of Medical Information,2018,31(06):115-116.[doi:10.3969/j.issn.1006-1959.2018.06.038]
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布拉氏酵母菌联合葡萄糖酸锌防治婴幼儿抗生素相关性腹泻临床效果观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年06期
页码:
115-116
栏目:
药物与临床
出版日期:
2018-03-20

文章信息/Info

Title:
Clinical Effect of Saccharomyces Brassicus Combined with Zinc Gluconate on the Prevention and Treatment of Antibiotic Associated Diarrhea in Infants
文章编号:
1006-1959（2018）06-0115-02
作者:
傅锡霖; 陈俊鸿; 季坚卫
浙江省义乌市中心医院儿科，浙江 义乌 322000
Author(s):
FU Xi-lin; CHEN Jun-hong; JI Jian-wei
Department of Pediatrics,Yiwu Central Hospital,Yiwu 322000,Zhejiang,China
关键词:
布拉氏酵母菌; 葡萄糖酸锌; 抗生素相关性肠炎
Keywords:
Key words：Saccharomyces boulardii; Zinc gluconate; Antibiotic associated colitis
分类号:
R725.7
DOI:
10.3969/j.issn.1006-1959.2018.06.038
文献标志码:
A
摘要:
目的 探讨布拉氏酵母菌联合葡萄糖酸锌在防治婴幼儿抗生素相关腹泻（AAD）中的临床效果。方法 选取2016年1月~2017年6月在我院儿科因肺炎住院需用抗生素治疗的患儿86例，随机分为观察组和对照组，各43例。观察组采用布拉氏酵母菌联合葡萄糖酸锌，对照组未给予任何益生菌及锌制剂，两组患儿均常规给予抗生素类药物及对症治疗。结果 观察组AAD发生率（23.26%）低于对照组（46.51%），两组比较差异有统计学意义（P＜0.05）；观察组AAD治疗总有效率（100.00%）高于对照组（55.00%），差异有统计学意义（P＜0.05）。结论 布拉氏酵母菌联合葡萄糖酸锌能有效降低婴幼儿肺炎患儿发生AAD的发生率，缩短AAD的病程，减轻ADD症状，未发现不良反应，值得在临床上推广应用。
Abstract:
Abstract：Objective To investigate the clinical effect of Saccharomyces cerevisiae combined with zinc gluconate in the prevention and treatment of antibiotic associated diarrhea in infants and children.Methods 86 children who were treated with antibiotics in the hospital of pediatrics in our hospital in January 2016~2017 and June were randomly divided into the observation group and the control group,each with 43 cases.The observation group with Saccharomyces boulardii combined with zinc gluconate,while the control group did not give any probiotics and zinc preparations,two groups were given conventional antibiotics and symptomatic treatment. Results The incidence of AAD in the observation group(23.26%)was lower than that in the control group(46.51%),and the difference between the two groups was statistically significant(P<0.05).The total effective rate of AAD in the observation group(100.00%)was higher than that in the control group(55.00%),and the difference was statistically significant(P<0.05).Conclusion Saccharomyces boulardii combined with zinc gluconate can effectively reduce the incidence of AAD in infants with pneumonia,shorten the course of AAD,reduce the symptoms of ADD,found no adverse reactions,worthy of clinical application.

参考文献/References:

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更新日期/Last Update: 2018-03-15