[1]张宏程.磷酸铝凝胶联合奥美拉唑治疗消化性溃疡的临床疗效观察[J].医学信息,2019,32(02):150-151.[doi:10.3969/j.issn.1006-1959.2019.02.044]
　ZHANG Hong-cheng.Clinical Efficacy of Aluminum Phosphate Gel Combined with Omeprazole in the Treatment of Peptic Ulcer[J].Journal of Medical Information,2019,32(02):150-151.[doi:10.3969/j.issn.1006-1959.2019.02.044]
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磷酸铝凝胶联合奥美拉唑治疗消化性溃疡的临床疗效观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年02期
页码:
150-151
栏目:
药物与临床
出版日期:
2019-01-15

文章信息/Info

Title:
Clinical Efficacy of Aluminum Phosphate Gel Combined with Omeprazole in the Treatment of Peptic Ulcer
文章编号:
1006-1959（2019）02-0150-02
作者:
张宏程
大连市普兰店区第二人民医院内科，辽宁 大连 116222
Author(s):
ZHANG Hong-cheng
Department of Internal Medicine,the Second People's Hospital,Pulandian District,Dalian 116222,Liaoning,China
关键词:
磷酸铝凝胶; 奥美拉唑; 消化性溃疡
Keywords:
Aluminum phosphate gel; Omeprazole; Peptic ulcer
分类号:
R573.1
DOI:
10.3969/j.issn.1006-1959.2019.02.044
文献标志码:
A
摘要:
目的 探讨磷酸铝凝胶联合奥美拉唑治疗消化性溃疡的临床疗效。方法 选取本院收治的消化性溃疡患者122例作为研究对象，随机分为观察组和对照组，每组61例。患者入院后均控制食物摄入，按常规补充水分及血容量。对照组患者在常规处理的基础上，口服奥美拉唑肠溶胶囊连续服用4周为一个疗程，服用前嘱患者空腹。观察组在对照组的基础上，再联合给予磷酸铝凝胶口服，服用前应摇匀，持续服用4周。对两组患者临床疗效及药物不良反应发生情况进行比较。结果 观察组患者总有效率为96.72%，高于对照组的86.88%，差异有统计学意义（
Abstract:
Objective To investigate the clinical efficacy of aluminum phosphate gel combined with omeprazole in the treatment of peptic ulcer. Methods A total of 122 patients with peptic ulcer admitted to our hospital were enrolled in the study. They were randomly divided into observation group and control group, with 61 cases in each group. The patient controls food intake after admission and replenishes water and blood volume as usual. On the basis of routine treatment, the patients in the control group received oral omeprazole enteric-coated capsules for 4 weeks as a course of treatment. The observation group was orally administered with an aluminum phosphate gel on the basis of the control group, and should be shaken before administration for 4 weeks. The clinical efficacy and adverse drug reactions of the two groups were compared. Results The total effective rate of the observation group was 96.72%, which was higher than that of the control group 86.88%,the difference was statistically significant (P<0.05). The incidence of adverse reactions was 9.84% in the observation group, which was lower than that in the control group 24.59%,the difference was statistically significant (P<0.05). Conclusion The clinical efficacy of aluminum phosphate gel combined with omeprazole in the treatment of peptic ulcer is better, which can effectively promote the healing of ulcer wounds, reduce the pain of patients, and have fewer adverse drug reactions.

参考文献/References:

[1]于磊,陈莹,万崇华.慢性消化性溃疡生命质量及患者报告结局的影响因素分析[J].重庆医学,2015(7):869-872.
[2]中华消化杂志编委会.消化性溃疡诊断与治疗规范[J].中华消化杂志,2016,36(8):508-513.
[3]谢代彬,王梅,贾雁平.消化性溃疡合并幽门螺杆菌感染患儿奥美拉唑四联疗法治疗效果分析[J].中华医院感染学杂志,2016,26(5):1146-1148.
[4]王炳英.埃索美拉唑、奥美拉唑为主的三联疗法治疗幽门螺杆菌阳性消化性溃疡效果比较[J].山东医药,2015,55(38):77-78.
[5]柴蓉蓉,孟鸽飞,丁佳宁,等.质子泵抑制药的药动学研究进展[J].中国药师,2017,20(2):331-333.

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更新日期/Last Update: 2019-02-15