[1]高华初.泮托拉唑治疗消化性溃疡合并上消化道出血的临床价值评价[J].医学信息,2018,31(22):153-154.[doi:10.3969/j.issn.1006-1959.2018.22.045]
 GAO Hua-chu.Clinical Value of Pantoprazole in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Bleeding[J].Journal of Medical Information,2018,31(22):153-154.[doi:10.3969/j.issn.1006-1959.2018.22.045]
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泮托拉唑治疗消化性溃疡合并上消化道出血的临床价值评价()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年22期
页码:
153-154
栏目:
药物与临床
出版日期:
2018-11-15

文章信息/Info

Title:
Clinical Value of Pantoprazole in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Bleeding
文章编号:
1006-1959(2018)22-0153-02
作者:
高华初
(都昌县人民医院消化内科,江西 九江 332600)
Author(s):
GAO Hua-chu
(Department of Gastroenterology,Duchang County People's Hospital,Jiujiang332600, Jiangxi,China)
关键词:
泮托拉唑奥美拉唑消化性溃疡上消化道出血
Keywords:
PantoprazoleOmeprazolePeptic ulcerUpper gastrointestinal bleeding
分类号:
R573.1;R573.2
DOI:
10.3969/j.issn.1006-1959.2018.22.045
文献标志码:
A
摘要:
目的 观察泮托拉唑治疗消化性溃疡合并上消化道出血的临床疗效。方法 选取2015年5月~2018年3月我院收治的100例消化性溃疡合并上消化道出血患者为研究对象,随机分为实验组和对照组,各50例。对照组患者采用奥美拉唑治疗,实验组患者采用泮托拉唑治疗。比较两组临床疗效及不良反应情况。结果 实验组治疗总有效率高于对照组(96.00% vs 80.00%),差异有统计学意义(P<0.05);实验组患者不良反应发生率低于对照组(6.00% vs 24.00%),差异有统计学意义(P<0.05)。结论 泮托拉唑治疗消化性溃疡合并上消化道出血临床疗效可靠,安全性高。
Abstract:
Objective To observe the clinical efficacy of pantoprazole in the treatment of peptic ulcer with upper gastrointestinal bleeding.Methods 100 patients with peptic ulcer complicated with upper gastrointestinal bleeding admitted to our hospital from May 2015 to March 2018 were randomly divided into experimental group and control group, 50 cases each. Patients in the control group were treated with omeprazole, and patients in the experimental group were treated with pantoprazole. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate of the experimental group was higher than that of the control group (96.00% vs 80.00%), the difference was statistically significant (P<0.05). The incidence of adverse reactions in the experimental group was lower than that of the control group (6.00% vs 24.00%),the difference was statistically significant (P<0.05). Conclusion Pantoprazole is a reliable and safe treatment of peptic ulcer with upper gastrointestinal bleeding.

参考文献/References:


[1]苏莹.生长抑素联合泮托拉唑治疗上消化道溃疡性出血的疗效观察[J].中国老年保健医学,2017,15(3):35-36.
[2]罗金键.泮托拉唑治疗消化性溃疡合并上消化道出血的临床观察[J].中国医院用药评价与分析,2015,15(3):301-304.
[3]金哲,周宝民,王大勇,等.泮托拉唑联合奥曲肽在消化性溃疡并上消化道出血的治疗应用[J].临床荟萃,2014,21(11):1299-1301.
[4]梁彩平,刘俏敏,张璋,等.奥曲肽联合泮托拉唑治疗老年患者消化性溃疡并出血疗效观察[J].中国当代医药,2013,20(3):80-81.
[5]杨晓霞.奥曲肽配伍泮托拉唑治疗消化性溃疡并发上消化道出血98例[J].陕西医学杂志,2016,45(9):1235-1236.
[6]黄光鸿,姚民武,钟文英,等.泮托拉唑联合云南白药对NSAID相关溃疡再出血和内镜表现的研究[J].当代医学,2014,21(35):1-2,3.
[7]侯艾林,贺汉军,唐建萍,等.上消化性出血患者使用泮托拉唑治疗的药效学及药动学分析[J].中国煤炭工业医学杂志,2015,18(9):1448-1451.

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更新日期/Last Update: 2018-12-03