[1]黄亚勇,师毅冰,陈国芳,等.颅内生殖细胞瘤的MRI影像表现及诊断[J].医学信息,2019,32(20):167-169,174.[doi:10.3969/j.issn.1006-1959.2019.20.053]
 HUANG Ya-yong,SHI Yi-bing,CHEN Guo-fang,et al.MRI Imaging Findings and Diagnosis of Intracranial Germ Cell Tumor[J].Journal of Medical Information,2019,32(20):167-169,174.[doi:10.3969/j.issn.1006-1959.2019.20.053]
点击复制

颅内生殖细胞瘤的MRI影像表现及诊断()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年20期
页码:
167-169,174
栏目:
诊疗技术
出版日期:
2019-10-15

文章信息/Info

Title:
MRI Imaging Findings and Diagnosis of Intracranial Germ Cell Tumor
文章编号:
1006-1959(2019)20-0167-04
作者:
黄亚勇1师毅冰1陈国芳2闫 军3
(1.徐州市中心医院CT室,江苏 徐州 221009;2.徐州市中心医院神经内科,江苏 徐州 221009;3.陕西勉县医院CT室,陕西 勉县 724200)
Author(s):
HUANG Ya-yong1SHI Yi-bing1CHEN Guo-fang2YAN Jun3
(1.CT Room,Xuzhou Central Hospital,Xuzhou 221009,Jiangsu,China;2.Department of Neurology,Xuzhou Central Hospital,Xuzhou 221009,Jiangsu,China;3.CT Room,Mianxian Hospital,Mianxian 724200,Shaanxi,China)
关键词:
生殖细胞瘤磁共振成像影像诊断
Keywords:
Germ cell tumorMagnetic resonance imagingImaging diagnosis
分类号:
R739.41;R445.2
DOI:
10.3969/j.issn.1006-1959.2019.20.053
文献标志码:
A
摘要:
目的 探讨颅内生殖细胞瘤的MRI表现,旨在提高对本病的影像诊断准确率。方法 回顾性分析2014年12月~2019年5月我院经手术病理或临床诊断性放射治疗确诊的13例颅内生殖细胞瘤患者的MRI影像资料,分析其临床表现、影像表现及诊断。结果 病变位于松果体区患者9例,MRI检查肿瘤实质部分T1WI呈稍低信号,T2WI和FLAIR 呈高或稍高信号,DWI呈等或稍高信号,增强扫描呈明显强化;肿瘤伴有囊变者1例,伴有钙化者3例,4例患者伴脑积水;3例患者出现转移灶,累及三脑室、侧脑室等,其MRI信号及强化方式与原发灶相似。病变位于鞍区患者3例,肿瘤形态、大小不一,T1WI 呈稍低信号,T2WI和FLAIR 呈稍高信号,增强扫描呈明显强化。1例患者的病变位于右侧基底节区,形态不规则,T1WI呈等信号,T2WI、FLAIR及DWI均呈稍高信号,增强扫描无强化,同侧大脑脚较对侧萎缩。结论 MRI对颅内生殖细胞瘤的影像诊断与鉴别诊断具有重要价值。
Abstract:
Objective To investigate the MRI findings of intracranial germ cell tumors in order to improve the accuracy of imaging diagnosis of this disease. Methods The MRI images of 13 patients with intracranial germ cell tumors diagnosed by surgical pathology or diagnostic radiotherapy in our hospital from December 2014 to May 2019 were retrospectively analyzed. The clinical manifestations, imaging findings and diagnosis were analyzed. Results There were 9 patients with lesions in the pineal region.MRI examination showed that the tumor parenchyma showed a slightly lower signal on T1WI, T2WI and FLAIR showed higher or slightly higher signal, DWI showed equal or slightly higher signal, enhanced scan showed obvious enhancement; tumor with cystic change in 1 case, accompanied by calcification in 3 cases 4 patients with hydrocephalus; 3 patients with metastases, involving the third ventricle, lateral ventricle, etc., MRI signal and enhancement methods similar to the primary lesion. There were 3 patients with lesions in the sellar region. The morphology and size of the tumors were different. T1WI showed a slightly lower signal, T2WI and FLAIR showed slightly higher signals, and enhanced scan showed obvious enhancement. The lesion of one patient was located in the right basal ganglia, and the shape was irregular. T1WI showed equal signals. T2WI, FLAIR and DWI showed slightly higher signals. The enhanced scan showed no enhancement, and the ipsilateral cerebral pedicle was atrophied.Conclusion MRI is of great value in the imaging diagnosis and differential diagnosis of intracranial germ cell tumor.

参考文献/References:

[1]孙晓非,杨群英.儿童原发中枢神经系统生殖细胞肿瘤多学科诊疗专家共识[J].中国小儿血液与肿瘤杂志,2018,23(6):281-286. [2]刘孟辉,彭双林,刘建玲,等.颅内不典型生殖细胞瘤MRI表现[J].临床放射学杂志,2017,36(8):1062-1066. [3]Gittleman H,Cioffi G,Vecchione-KovalT,et al.Descriptive epidemiology of germ cell tumors ofthe central nervous system diagnosed in the United States from 2006 to 2015[J].J Neurooncol,2019,143(2):251-260. [4]Louis DN,Perry A,ReifenbergerG,et al.The 2016 World Health Organization Classification of Tumors of the Central Nervous System:a summary[J].Acta Neuropathol,2016,131(6):803-820. [5]丁建峰,薛伟,郭兴华.颅内生殖细胞瘤的影像诊断与临床分析[J].中国药物与临床,2018,18(8):1317-1318. [6]韩磊,王新岭,张善红.颅内生殖细胞瘤MRI影像表现及诊断分析[J].泰山医学院学报,2017,38(3):331-332. [7]武乐乐.儿童及青少年松果体区生殖细胞肿瘤的CT、MRI表现[J].中国CT和MRI杂志,2018,16(12):1-3,23. [8]张大千,李桥,何慧瑾,等.基底节区生殖细胞瘤的MRI和MRS征象分析[J].中国医学计算机成像杂志,2017,23(2):101-106. [9]Cucc IAV,Galarza M.Purepineal germinomas anaysis of genderincidence[J].Acta Neurochir,2006,148(8):865-871. [10]石磊,刘福尧.颅内生殖细胞瘤MRI影像表现及鉴别诊断[J].现代医用影像学,2015,24(5):746-748. [11]柴成奎,周俊林,毛俊杰,等.颅内松果体区少见类型生殖细胞肿瘤的MRI表现[J].中华放射学杂志,2014,48(11):902-905. [12]白玉萍,张静,欧阳红,等.鞍区生殖细胞瘤的MRI及MRS表现[J].影像研究与医学应用,2018,2(15):145-147. [13]Phi JH,Cho BK,Kim SK,et al.Germinomas in the basal ganglia:magnetic resonance imaging classifications and the prognosis[J].J Neurooncol,2010,99(2):227-236. [14]Kim CH,Paek SH,Park IA,et al.Cerebral germinoma with hemiatrophy of the brain:report of three cases[J].Acta Neurochirurgica,2002,144(2):145-150. [15]Tso WW,Yung AW,Lau HY,et al.Basal ganglia germinoma: MRI classificationcorrelates well with neurological and cognitive outcome[J].J Pediatr Hematol Oncol,2014,36(7):e443-e447.

相似文献/References:

[1]雷少晖,张永海.脑氧代谢的影像学测定方法研究[J].医学信息,2018,31(05):38.[doi:10.3969/j.issn.1006-1959.2018.05.015]
 LEI Shao-hui,ZHANG Yong-hai.Imaging Study of Brain Oxygen Metabolism[J].Journal of Medical Information,2018,31(20):38.[doi:10.3969/j.issn.1006-1959.2018.05.015]
[2]管海生.膝关节剥脱性骨软骨炎MRI诊断[J].医学信息,2018,31(06):158.[doi:10.3969/j.issn.1006-1959.2018.06.056]
 GUAN Hai-sheng.MRI Diagnosis of Exfoliative Osteochondritis in Knee Joint[J].Journal of Medical Information,2018,31(20):158.[doi:10.3969/j.issn.1006-1959.2018.06.056]
[3]王国杰,梁日晶,刘 莹,等.3.0T磁共振扩散张量成像与扩散加权成像对单发大脑半球胶质瘤病理分级的诊断价值[J].医学信息,2022,35(09):104.[doi:10.3969/j.issn.1006-1959.2022.09.026]
 WANG Guo-jie,LIANG Ri-jing,LIU Ying,et al.Diagnostic Value of 3.0T Magnetic Resonance Diffusion Tensor Imaging and Diffusion Weighted Imaging in Pathological Grading of Single Cerebral Hemispheric Glioma[J].Journal of Medical Information,2022,35(20):104.[doi:10.3969/j.issn.1006-1959.2022.09.026]
[4]张 虎,张 涛,徐 芳,等.MRI在乳腺癌诊治中的研究进展[J].医学信息,2022,35(10):62.[doi:10.3969/j.issn.1006-1959.2022.10.015]
 ZHANG Hu,ZHANG Tao,XU Fang,et al.Research Progress of MRI in Diagnosis and Treatment of Breast Cancer[J].Journal of Medical Information,2022,35(20):62.[doi:10.3969/j.issn.1006-1959.2022.10.015]
[5]孔俊沣,钟 雯,刘 嵩,等.MRI对卵巢子宫内膜异位囊肿的诊断价值[J].医学信息,2022,35(11):165.[doi:10.3969/j.issn.1006-1959.2022.11.044]
 KONG Jun-feng,ZHONG Wen,LIU Song,et al.The Diagnostic Value of MRI in Ovarian Endometriotic Cyst[J].Journal of Medical Information,2022,35(20):165.[doi:10.3969/j.issn.1006-1959.2022.11.044]
[6]刘 钢,李志伟,田 晞,等.磁共振检查对冯·希佩尔·林道综合征诊断的意义[J].医学信息,2018,31(18):145.[doi:10.3969/j.issn.1006-1959.2018.18.047]
 LIU Gang,LI Zhi-wei,TIAN Xi,et al.The Significance of Magnetic Resonance Examination in the Diagnosis of Von Hippel-Lindau Disease[J].Journal of Medical Information,2018,31(20):145.[doi:10.3969/j.issn.1006-1959.2018.18.047]
[7]马平平,程宇琪,许秀峰,等.抑郁症脑磁共振成像与抗抑郁治疗临床改善间关系的研究进展[J].医学信息,2018,31(24):31.[doi:10.3969/j.issn.1006-1959.2018.24.009]
 MA Ping-ping,CHENG Yu-qi,XU Xiu-feng,et al.Advances in Research on the Relationship between Brain Magnetic Resonance Imaging and Clinical Improvement of Antidepressant Therapy[J].Journal of Medical Information,2018,31(20):31.[doi:10.3969/j.issn.1006-1959.2018.24.009]
[8]刘姗灵,冉 冉,涂 刚.乳腺Paget′s 病诊断与治疗相关研究进展[J].医学信息,2019,32(07):1.[doi:10.3969/j.issn.1006-1959.2019.07.001]
 LIU Shan-ling,RAN Ran,TU Gang.Advances in Research on Diagnosis and Treatment of Paget's Disease in Breast[J].Journal of Medical Information,2019,32(20):1.[doi:10.3969/j.issn.1006-1959.2019.07.001]
[9]蔡 彬,黄 伟,储正达,等.直肠腔内超声与相控阵线圈磁共振在直肠癌术前局部分期中的Meta分析[J].医学信息,2019,32(10):70.[doi:10.3969/j.issn.1006-1959.2019.10.024]
 CAI Bin,HUANG Wei,CHU Zheng-da,et al.Meta-analysis of Intra-rectal Ultrasound and Phased-array Magnetic Resonance in the Preoperative Partial Phase of Rectal Cancer[J].Journal of Medical Information,2019,32(20):70.[doi:10.3969/j.issn.1006-1959.2019.10.024]
[10]王 刚,余芬芬,吴依芬,等.基于MRI成像的影像组学特征识别肺癌肺外转移特性的价值[J].医学信息,2022,35(14):41.[doi:10.3969/j.issn.1006-1959.2022.14.008]
 WANG Gang,YU Fen-fen,WU Yi-fen,et al.Value of Radiomic Features Based on MRI in Identifying Extrapulmonary Metastasis of Lung Cancer[J].Journal of Medical Information,2022,35(20):41.[doi:10.3969/j.issn.1006-1959.2022.14.008]

更新日期/Last Update: 2019-10-15