[1]郭 达,吕松岑.创伤性踝关节炎相关机制及治疗研究[J].医学信息,2020,33(01):54-56.[doi:10.3969/j.issn.1006-1959.2020.01.018]
 GUO Da,Lyu Song-cen.Study on the Related Mechanism and Treatment of Traumatic Ankle Arthritis[J].Medical Information,2020,33(01):54-56.[doi:10.3969/j.issn.1006-1959.2020.01.018]
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创伤性踝关节炎相关机制及治疗研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年01期
页码:
54-56
栏目:
综述
出版日期:
2020-01-01

文章信息/Info

Title:
Study on the Related Mechanism and Treatment of Traumatic Ankle Arthritis
文章编号:
1006-1959(2020)01-0054-03
作者:
郭 达吕松岑
(哈尔滨医科大学附属第二医院骨四科,黑龙江 哈尔滨 150086)
Author(s):
GUO DaLyu Song-cen
(Department of Orthopaedics,Subject Four,the Second Affiliated Hospital of Harbin Medical University,Harbin 150086,Heilongjiang,China)
关键词:
创伤性踝关节炎骨折炎症因子生物工程
Keywords:
Traumatic ankle arthritisFractureInflammatory factorsBioengineering
分类号:
R684.3
DOI:
10.3969/j.issn.1006-1959.2020.01.018
文献标志码:
A
摘要:
创伤性踝关节炎是以关节剧烈疼痛、活动严重受限为主要临床表现的骨关节炎,其特点为关节损伤和软骨退变。目前对于创伤性踝关节炎的研究较少,其确切机制尚不明确。对于创伤性踝关节炎的治疗主要以外科手术为主,而一些新型治疗理念也不断被接受。本文从影响创伤性踝关节炎的物理及生理因素两方面阐述其相关机制,包括骨折能量分布、踝关节生物力学、促炎细胞因子和代谢物的作用,同时根据发病机制提出抑制氧化,细胞因子抑制、组织工程的临床治疗思路作一综述。
Abstract:
Traumatic ankle arthritis is osteoarthritis whose main clinical manifestations are severe joint pain and severely restricted movement. It is characterized by joint damage and cartilage degeneration. There are few studies on traumatic ankle arthritis, and the exact mechanism is not clear. The treatment of traumatic ankle arthritis is mainly surgical, and some new treatment concepts have been continuously accepted. This article describes the related mechanisms from physical and physiological factors affecting traumatic ankle arthritis, including fracture energy distribution, ankle biomechanics, proinflammatory cytokines and metabolites, and proposes inhibition of oxidation and cytokines according to the pathogenesis The clinical treatment ideas of inhibition and tissue engineering are reviewed.

参考文献/References:

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更新日期/Last Update: 2020-01-01