[1]胡 岩.蔗糖铁联合重组人促红细胞生成素注射液治疗血液透析患者肾性贫血的疗效[J].医学信息,2021,34(14):157-159.[doi:10.3969/j.issn.1006-1959.2021.14.044]
　HU Yan.Effect of Sucrose Iron Combined with Recombinant Human Erythropoietin Injection on Renal Anemia in Hemodialysis Patients[J].Medical Information,2021,34(14):157-159.[doi:10.3969/j.issn.1006-1959.2021.14.044]
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蔗糖铁联合重组人促红细胞生成素注射液治疗血液透析患者肾性贫血的疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年14期
页码:
157-159
栏目:
药物与临床
出版日期:
2021-07-15

文章信息/Info

Title:
Effect of Sucrose Iron Combined with Recombinant Human Erythropoietin Injection on Renal Anemia in Hemodialysis Patients
文章编号:
1006-1959（2021）14-0157-03
作者:
胡 岩
（辽宁省盘锦市大洼区人民医院血液透析室，辽宁 盘锦 124200）
Author(s):
HU Yan
(Hemodialysis Room,People’s Hospital of Dawa District,Panjin 124200,Liaoning,China)
关键词:
血液透析; 肾性贫血; 重组人促红细胞生成素注射液; 蔗糖铁
Keywords:
Hemodialysis; Renal anemia; Recombinant human erythropoietin injection; Sucrose iron
分类号:
R556
DOI:
10.3969/j.issn.1006-1959.2021.14.044
文献标志码:
A
摘要:
目的 探讨蔗糖铁联合重组人促红细胞生成素注射液治疗血液透析患者肾性贫血的疗效。方法 选取2019年5月~2020年10月我院接受血液透析并存在不同程度肾性贫血患者78例作为研究对象，根据随机双目盲选法分为实验组和常规组，每组39例。常规组给予重组人促红细胞生成素注射液治疗，实验组在常规组用药基础上联合使用蔗糖铁治疗，比较两组临床治疗疗效、贫血指标、铁指标、炎性因子指标及不良反应发生情况。结果 实验组临床治疗总有效率为94.88%，高于常规组的74.36%（P＜0.05）。实验组Hb、RBC、HCT、SF、SI、TSAT高于常规组，TIBC低于常规组（P＜0.05）。两组CRP、IL-6、IL-8水平比较，差异无统计学意义（P＞0.05）。两组不良反应总发生率比较，差异无统计学意义（P＞0.05）。结论 蔗糖铁联合重组人促红细胞生成素注射液治疗血液透析患者肾性贫血的疗效确切，可改善肾性贫血症状，且用药安全性高。
Abstract:
Objective To investigate the efficacy of iron sucrose combined with recombinant human erythropoietin injection in the treatment of renal anemia in hemodialysis patients.Methods From May 2019 to October 2020, 78 patients with renal anemia in our hospital who underwent hemodialysis and had different degrees of renal anemia were selected as the research objects. According to the random binocular blind selection method, they were divided into experimental group and routine group, with 39 cases in each group.The conventional group was treated with recombinant human erythropoietin injection, and the experimental group was treated with iron sucrose on the basis of the conventional group.Comparison of the clinical treatment efficacy, anemia indicators, iron indicators, inflammatory factors and adverse reactions.Results The total effective rate of clinical treatment in the experimental group was 94.88%, which was higher than the 74.36% in the conventional group(P<0.05).The Hb, RBC, HCT, SF, SI, TSAT of the experimental group were higher than those of the conventional group, the TIBC of the experimental group was lower than that of the conventional group(P<0.05).There was no significant difference in the levels of CRP, IL-6, and IL-8 between the two groups (P>0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of iron sucrose and recombinant human erythropoietin injection is effective in treating renal anemia in hemodialysis patients. It can improve the symptoms of renal anemia, and the medication is safe.

参考文献/References:

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更新日期/Last Update: 1900-01-01