[1]彭 迁,吕 媛.HIV/AIDS患者服药依从性影响因素的Meta分析[J].医学信息,2021,34(17):7-14.[doi:10.3969/j.issn.1006-1959.2021.17.003]
 PENG Qian,LYU Yuan.Meta-analysis of Factors Influencing HIV/AIDS Patients’ Medication Compliance[J].Medical Information,2021,34(17):7-14.[doi:10.3969/j.issn.1006-1959.2021.17.003]
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HIV/AIDS患者服药依从性影响因素的Meta分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年17期
页码:
7-14
栏目:
出版日期:
2021-09-01

文章信息/Info

Title:
Meta-analysis of Factors Influencing HIV/AIDS Patients’ Medication Compliance
文章编号:
1006-1959(2021)17-0007-08
作者:
彭 迁吕 媛
(湖南师范大学医学院,湖南 长沙 410006)
Author(s):
PENG QianLYU Yuan
(Hunan Normal University School of Medicine,Changsha 410006,Hunan,China)
关键词:
HIV/AIDS服药依从性按时服药率提醒服药家庭支持治疗
Keywords:
HIV/AIDSMedication compliancePunctual medication rateMedication reminderFamily supportive treatment
分类号:
R512.91;R181.3+2
DOI:
10.3969/j.issn.1006-1959.2021.17.003
文献标志码:
A
摘要:
目的 探讨中国HIV/AIDS患者服药依从性的影响因素,为艾滋病的预防控制提供参考依据。方法 在中国知网、万方、维普、中国生物医药数据库检索2008年1月-2021年3月中文文献,在PubMed、Cochrane Library、Web of Science和EMbase数据库检索同期发表的外文文献;应用RevMan 5.3软件对纳入文献进行Meta分析。结果 共检索出相关中文、英文文献995篇,根据纳入与排除标准,最终纳入文献共21篇,其中中文17篇,英文4篇,共调查人数5923例,其中4653例服药依从性较好,占总数78.56%。对纳入的影响因素进行Meta分析结果显示,不同年龄(OR=1.50,95%CI=0.95~2.38)、性别(OR=0.83,95%CI=0.70~0.98)、月收入(OR=0.72,95%CI=0.56~0.92)、文化程度(OR=0.49,95%CI=0.56~0.92)、婚姻状况(OR=1.34,95%CI=1.01~1.38)、治疗认知(OR=2.74,95%CI=1.76~4.27)、居住状况(OR=0.56,95%CI=0.29~1.06)、不良反应(OR=0.5,95%CI=0.29~0.84)、提醒服药(OR=2.78,95%CI=1.49~5.17)、饮酒(OR=0.51,95%CI=0.27~0.97)服药依从性比较,差异有统计学意义(P<0.1)。结论 性别、年龄、婚姻状况、月收入、文化程度、治疗认知、居住情况、不良反应、提醒服药及饮酒是影响艾滋患者服药依从性的主要因素。
Abstract:
Objective To explore the factors influencing the compliance of Chinese HIV/AIDS patients with medication, and to provide a reference for the prevention and control of AIDS.Methods Searching Chinese documents in CNKI, Wanfang, Weipu, China Biomedicine Database, and foreign literature published in PubMed, Cochrane Library, Web of Science and Embase databases from January 2008 to March 2021;RevMan 5.3 software was used to conduct Meta analysis of the included literature.Results A total of 995 relevant Chinese and English documents were retrieved in this article.According to the inclusion and exclusion criteria, a total of 21 articles were finally included, including 17 in Chinese and 4 in English. A total of 5923 cases were investigated, and 4653 cases had good medication compliance, accounting for 78.56% of the total.Meta-analysis of the included influencing factors showed that different age (OR=1.50, 95%CI=0.95-2.38), gender (OR=0.83,95%CI=0.70-0.98), monthly income (OR=0.72,95 %CI=0.56-0.92), education level (OR=0.49, 95%CI=0.56-0.92), marital status (OR=1.34, 95%CI=1.01-1.38), treatment cognition (OR=2.74, 95% CI=1.76-4.27), residence status (OR=0.56, 95%CI=0.29-1.06), adverse reactions (OR=0.50, 95%CI=0.29-0.84), remindes to take medication (OR=2.78, 95%CI=1.49-5.17),drinking (OR=0.51, 95%CI=0.27-0.97) medication compliance,the difference was statistically significant (P<0.1). Conclusion Gender, age, marital status, monthly income, education level, treatment cognition, living conditions, adverse reactions, reminders to take medication and drinking are the main factors affecting the compliance of AIDS patients.

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更新日期/Last Update: 1900-01-01