[1]张俊霞.慢性期痛风性关节炎超声表现与血尿酸水平的相关性[J].医学信息,2022,35(20):151-153.[doi:10.3969/j.issn.1006-1959.2022.20.042]
　ZHANG Jun-xia.Correlation Between Ultrasonic Manifestations of Chronic Gouty Arthritis and Serum Uric Acid Level[J].Journal of Medical Information,2022,35(20):151-153.[doi:10.3969/j.issn.1006-1959.2022.20.042]
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慢性期痛风性关节炎超声表现与血尿酸水平的相关性()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年20期
页码:
151-153
栏目:
诊疗技术
出版日期:
2022-10-15

文章信息/Info

Title:
Correlation Between Ultrasonic Manifestations of Chronic Gouty Arthritis and Serum Uric Acid Level
文章编号:
1006-1959（2022）20-0151-03
作者:
张俊霞
（天津港口医院功能检查科，天津 300450）
Author(s):
ZHANG Jun-xia
(Department of Functional Examination,Tianjin Port Hospital,Tianjin 300450,China)
关键词:
慢性期痛风性关节炎; 超声; 血尿酸
Keywords:
Chronic gouty arthritis; Ultrasound; Blood uric acid
分类号:
R589.7；R445.1；R446.11
DOI:
10.3969/j.issn.1006-1959.2022.20.042
文献标志码:
A
摘要:
目的 研究慢性期痛风性关节炎超声表现与血尿酸水平的相关性。方法 选取2020年7月-2021年7月在我院诊治的70例慢性期痛风性关节炎患者为研究对象，均进行超声检查，观察超声表现特点、不同超声表现患者血尿酸水平，并进一步分析超声表现与血尿酸水平的相关性。结果 70例患者中87.14%的患者存在关节积液，55.71%存在痛风石，51.42%的患者伴关节滑膜增生，57.14%的患者存在双轨征，28.57%的患者存在关节内及周围高回声云雾区，24.28%的患者存在骨质侵蚀；不同关节积液最大深度、关节滑膜厚度患者血尿酸水平比较，差异有统计学意义（P＜0.05）；不同痛风石径线、是否存在关节内及周围高回声云雾区、双轨征、骨侵蚀血尿酸水平比较，差异无统计学意义（P＞0.05）；Pearson分析显示，关节积液最大深度与血尿酸水平呈正相关（P＜0.05），与关节滑膜厚度无明显相关性（P＞0.05）。结论 慢性期痛风性关节炎关节积液最大深度与血尿酸水平具有正相关性，可作为临床疗效、病情监测的超声重要指标，值得临床予以重视和关注。
Abstract:
Objective To study the correlation between ultrasonic manifestations of chronic gouty arthritis and serum uric acid level.Methods A total of 70 patients with chronic gouty arthritis diagnosed and treated in our hospital from July 2020 to July 2021 were selected as the research objects. All patients underwent ultrasound examination to observe the characteristics of ultrasound manifestations and blood uric acid levels in patients with different ultrasound manifestations, and further analyze the correlation between ultrasound manifestations and blood uric acid levels.Results Among the 70 patients, 87.14% had joint effusion, 55.71% had tophite, 51.42% had joint synovial hyperplasia, 57.14% had double-track signs, 28.57% had high echo cloud area in and around the joint, and 24.28% had bone erosion. There were statistically significant differences in blood uric acid level among patients with different maximum depth of joint effusion and joint synovial thickness (P<0.05). There was no significant difference in blood uric acid level among different gout stone paths, whether there was high echo cloud area in and around joints, double track sign and bone erosion (P>0.05). Pearson analysis showed that the maximum depth of joint effusion was positively correlated with blood uric acid level (P<0.05), but had no significant correlation with synovial membrane thickness (P>0.05).Conclusion The maximum depth of joint effusion in chronic gouty arthritis is positively correlated with the level of blood uric acid, which can be used as an important ultrasonic index for clinical efficacy and disease monitoring, and deserves clinical attention and attention.

参考文献/References:

[1]王海霞.非布司他联合塞来昔布治疗痛风性关节炎的临床疗效观察[J].中国药物与临床,2019,19(5):759-761.[2]谢伟,米晋,朱晓敏.CT及磁共振成像诊断痛风性关节炎的准确性对比及影像特征分析[J].山西医药杂志,2019,48(14):1676-1677.[3]隋文倩,陈秀晓,吴圆圆.高频超声检查与双源CT诊断痛风性关节炎的价值比较[J].临床合理用药杂志,2017,10(10):124-125.[4]梁慧英,廖琳,何善智,等.中西医结合分期治疗慢性期痛风性关节炎30例临床观察[J].中医杂志,2015,56(2):136-139.[5]于登锋,袁志红.高频超声、X线、CT在痛风性关节炎诊断中的应用比较[J].医药论坛杂志,2017,38(9):85-86,89.[6]张景锋,张春峰,张红艳,等.高频超声联合X线检查对痛风性关节炎患者关节损害的诊断价值[J].陕西医学杂志,2017,46(10):1428-1429.[7]Gamala M,Linn-Rasker SP,Nix M,et al.Gouty arthritis: decision making following dualenergy CT scan in clinical practice,a retrospective analysis[J].Clin Rheumat,2018,37(7):1879-1884.[8]张玮婧,金志斌,孔文韬,等.超声造影对类风湿性关节炎目标治疗前后滑膜血流灌注变化的评估[J].中国超声医学杂志,2019,35(8):764-767.[9]Basaric MM,Damjanov N,Perovic-Radak M.AB1040 Is gout a chronic inflammatory disease of a low level of activity[J].Annals of the Rheumatic Diseases,2018,77:1635-1636.[10]王小静,张莉芸,李娟,等.肌肉骨骼超声用于痛风诊断和病情监测[J].中华临床免疫和变态反应杂志,2016,10(2):164-169.[11]钱凯,张筠雩,李春梅,等.血尿酸不高的急性痛风患者血清中IL-6、IL-1β和炎症指标的表达水平及临床意义分析[J].标记免疫分析与临床,2018,25(2):183-185.[12]邱艺琼,马晓芹.关节超声对痛风关节炎急性发作期的诊断价值[J].临床医学,2018,38(9):7-9.[13]韩晓凤.双能量CT与高频超声诊断痛风性关节炎63例的临床分析[J].中国CT和MRI杂志,2018,16(5):134-136,146.[14]Ottaviani S,Gill G,Aubrun A,et al.Ultrasound in gout: A useful tool for following urate-lowering therapy[J].Joint Bone Spine,2016,82:42-44.[15]邓玉莲,钟逢逍,黄淑卿.高频超声对痛风性关节炎关节损害患者的诊断作用[J].生物医学工程学进展,2020,41(2):101-103.[16]任洁,周毅,吴会霞,等.双能CT检查在痛风性关节炎中的应用价值[J].南方医科大学学报,2015(3):384-386.[17]刘洁,刘安,景香香.高频超声对高尿酸血症患者并发痛风性关节炎的诊断价值[J].中国老年学杂志,2019,39(6):2947-2949.[18]周慧,吴秀英,崔凌凌,等.痛风与非痛风人群高血压相关因素对比分析[J].中华内分泌代谢杂志,2017,33(2):98-102.[19]朱永涛,刘广会,郭玲,等.慢性期痛风性关节炎超声表现与血尿酸水平相关性分析[J].现代中西医结合杂志,2019,28(28):3127-3129.[20]Yang L,Zhao Q,Yin Y,et al.Serum levels of IL-17 are elevated in patients with acute gouty arthritis[J].Oncotarget,2017,8(26):42510-42524.

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更新日期/Last Update: 1900-01-01