[1]叶小波.硒酵母片、左甲状腺素钠片联合维生素D治疗桥本甲状腺炎伴甲状腺功能减退的疗效[J].医学信息,2023,36(17):154-156.[doi:10.3969/j.issn.1006-1959.2023.17.032]
 YE Xiao-bo.Efficacy of Selenious Yeast Tablets, Levothyroxine Sodium Tablets Combined with Vitamin D in the Treatment of Hashimoto’s Thyroiditis with Hypothyroidism[J].Journal of Medical Information,2023,36(17):154-156.[doi:10.3969/j.issn.1006-1959.2023.17.032]
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硒酵母片、左甲状腺素钠片联合维生素D治疗桥本甲状腺炎伴甲状腺功能减退的疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年17期
页码:
154-156
栏目:
药物与临床
出版日期:
2023-09-01

文章信息/Info

Title:
Efficacy of Selenious Yeast Tablets, Levothyroxine Sodium Tablets Combined with Vitamin D in the Treatment of Hashimoto’s Thyroiditis with Hypothyroidism
文章编号:
1006-1959(2023)17-0154-03
作者:
叶小波
(青铜峡市人民医院内分泌科,宁夏 青铜峡 751600)
Author(s):
YE Xiao-bo
(Department of Endocrinology,Qingtongxia People’s Hospital,Qingtong xia 751600,Ningxia,China)
关键词:
桥本甲状腺炎甲状腺功能减退症硒酵母片维生素D
Keywords:
Hashimoto’s thyroiditisHypothyroidismSelenious yeast tabletsVitamin D
分类号:
R581
DOI:
10.3969/j.issn.1006-1959.2023.17.032
文献标志码:
A
摘要:
目的 观察硒酵母片、左甲状腺素钠片联合维生素D治疗桥本甲状腺炎(HT)伴甲状腺功能减退症患者的临床效果。方法 选取2019年1月-2021年4月我院收治的60例HT伴甲状腺功能减退症患者,随机分为对照组和研究组,每组30例。对照组予以硒酵母片+左甲状腺素钠片治疗,研究组在对照组基础上联合维生素D治疗,比较两组血游离甲状腺素(FT4)、促甲状腺素(TSH)、甲状腺过氧化物酶抗体(TPO-ab)、25羟维生素[25(OH)VD]水平。结果 治疗12周后,研究组FT4、25(OH)VD水平高于对照组,TPO-ab、TSH水平低于对照组,差异有统计学意义(P<0.05)。结论 在左甲状腺素钠片、硒酵母片基础上,联合维生素D治疗可降低HT伴甲状腺功能减退患者过氧化物酶抗体水平、改善患者甲状腺功能。
Abstract:
Objective To observe the clinical effect of selenious yeast tablets, levothyroxine sodium tablets combined with vitamin D in the treatment of Hashimoto’s thyroiditis (HT) with hypothyroidism.Methods Sixty patients with HT and hypothyroidism admitted to our hospital from January 2019 to April 2021 were randomly divided into control group and study group, with 30 patients in each group. The control group was treated with selenious yeast tablets+levothyroxine sodium tablets, and the study group was treated with vitamin D on the basis of the control group. The levels of free thyroxine (FT4), thyroid stimulating hormone (TSH), thyroid peroxidase antibody (TPO-ab) and 25-hydroxyvitamin [25(OH)VD] were compared between the two groups.Results After 12 weeks of treatment, the levels of FT4 and 25(OH)VD in the study group were higher than those in the control group, and the levels of TPO-ab and TSH were lower than those in the control group, the differences were statistically significant (P<0.05).Conclusion On the basis of levothyroxine sodium tablets and selenious yeast tablets, combined with vitamin D treatment can reduce the level of peroxidase antibody and improve the thyroid function of HT patients with hypothyroidism.

参考文献/References:

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更新日期/Last Update: 1900-01-01