[1]周 宏.缩宫素联合卡贝缩宫素在剖宫产术中子宫收缩乏力引起产后出血中的临床疗效及对血流动力学的影响[J].医学信息,2023,36(23):62-65.[doi:10.3969/j.issn.1006-1959.2023.23.015]
　ZHOU Hong.Clinical Efficacy of Oxytocin Combined with Carbetocin in Postpartum Hemorrhage Caused by Uterine Atony During Cesarean Section and its Effect on Hemodynamics[J].Journal of Medical Information,2023,36(23):62-65.[doi:10.3969/j.issn.1006-1959.2023.23.015]
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缩宫素联合卡贝缩宫素在剖宫产术中子宫收缩乏力引起产后出血中的临床疗效及对血流动力学的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年23期
页码:
62-65
栏目:
论著
出版日期:
2023-12-01

文章信息/Info

Title:
Clinical Efficacy of Oxytocin Combined with Carbetocin in Postpartum Hemorrhage Caused by Uterine Atony During Cesarean Section and its Effect on Hemodynamics
文章编号:
1006-1959（2023）23-0062-04
作者:
周 宏
（崇仁县中医院妇产科，江西 崇仁 344200）
Author(s):
ZHOU Hong
(Department of Obstetrics and Gynecology,Chongren County Hospital of Traditional Chinese Medicine,Chongren 344200,Jiangxi,China)
关键词:
产后出血; 子宫收缩乏力; 缩宫素; 卡贝缩宫素; 血流动力学
Keywords:
Postpartum hemorrhage; Uterine atony; Oxytocin; Carboxytocin; Hemodynamics
分类号:
R714.69
DOI:
10.3969/j.issn.1006-1959.2023.23.015
文献标志码:
A
摘要:
目的 研究缩宫素联合卡贝缩宫素在剖宫产术中子宫收缩乏力引起产后出血中的临床疗效及对血流动力学的影响。方法 以2019年5月-2022年5月崇仁县中医院行剖宫产分娩且出现术中子宫收缩乏力的60例产妇为研究对象，按照随机数字表法分为对照组（30例）与观察组（30例）。对照组给予缩宫素干预，观察组给予缩宫素联合卡贝缩宫素干预，比较两组产后出血情况（术后2、24 h出血量及产后出血率）、血红蛋白（Hb）、血流动力学指标[收缩压（SBP）、舒张压（DBP）、心率（HR）]、不良反应。结果 观察组术后2、24 h出血量少于对照组，且产后出血率小于对照组（P＜0.05）。两组术后24 h的Hb水平较术前降低（P＜0.05），但组间比较，差异无统计学意义（P＞0.05）；而观察组Hb下降值小于对照组（P＜0.05）。两组术后24 h 的SBP、DBP水平低于术前，HR高于术前，但观察组SBP、DBP水平高于对照组，HR低于对照组（P＜0.05）。观察组不良反应发生率小于对照组（P＜0.05）。结论 缩宫素联合卡贝缩宫素可有效改善剖宫产术中子宫收缩乏力引起的出血情况，降低产后出血风险，减少血红蛋白流失及血流动力学波动，且具有良好安全性。
Abstract:
Objective To study the clinical efficacy of oxytocin combined with carbetocin in postpartum hemorrhage caused by uterine atony during cesarean section and its effect on hemodynamics.Methods From May 2019 to May 2022, 60 parturients who underwent cesarean section and had intraoperative uterine atony in Chongren County Hospital of Traditional Chinese Medicine were selected as the research objects. They were divided into control group (30 parturients) and observation group (30 parturients) according to the random number table method. The control group was given oxytocin intervention, and the observation group was given oxytocin combined with carbetocin intervention. The postpartum hemorrhage (bleeding volume and postpartum hemorrhage rate at 2 and 24 h after operation), hemoglobin (Hb), hemodynamic indexes [systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR)] and adverse reactions were compared between the two groups.Results The amount of bleeding at 2 and 24 h after operation in the observation group was less than that in the control group, and the rate of postpartum hemorrhage was less than that in the control group (P<0.05). The level of Hb in the two groups at 24 h after operation was lower than that before operation (P<0.05), but there was no significant difference between the two groups (P>0.05), while the decrease of Hb in the observation group was less than that in the control group (P<0.05). The levels of SBP and DBP at 24 h after operation in the two groups were lower than those before operation, and HR was higher than that before operation, but the levels of SBP and DBP in the observation group were higher than those in the control group, and HR was lower than that in the control group (P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05).Conclusion Oxytocin combined with Carboxytocin can effectively improve the bleeding caused by uterine atony during cesarean section, reduce the risk of postpartum hemorrhage, reduce hemoglobin loss and hemodynamic fluctuations, and has good safety.

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更新日期/Last Update: 1900-01-01