[1]邓 伟.血必净注射液预防STEMI患者直接介入治疗后冠脉无复流的效果[J].医学信息,2020,33(17):163-165.[doi:10.3969/j.issn.1006-1959.2020.17.049]
　DENG Wei.Effect of Xuebijing Injection in Preventing Coronary Artery No-reflow After Direct Interventional Therapy in STEMI Patients[J].Medical Information,2020,33(17):163-165.[doi:10.3969/j.issn.1006-1959.2020.17.049]
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血必净注射液预防STEMI患者直接介入治疗后冠脉无复流的效果()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年17期
页码:
163-165
栏目:
中医中药
出版日期:
2020-09-01

文章信息/Info

Title:
Effect of Xuebijing Injection in Preventing Coronary Artery No-reflow After Direct Interventional Therapy in STEMI Patients
文章编号:
1006-1959（2020）17-0163-03
作者:
邓 伟
（天津市武清区中医医院，天津 301700）
Author(s):
DENG Wei
(Wuqing District Traditional Chinese Medicine Hospital,Tianjin 301700,China)
关键词:
急性ST段抬高型心肌梗死; 介入治疗; 无复流; 血必净
Keywords:
Acute ST-segment elevation myocardial infarction; Interventional therapy; No reflow;  Xuebijing
分类号:
R541.4
DOI:
10.3969/j.issn.1006-1959.2020.17.049
文献标志码:
A
摘要:
目的 探讨血必净注射液预防急性ST段抬高型心肌梗死（STEMI）患者直接介入治疗后冠脉无复流的效果。方法 选取2016年6月~2017年9月我院接受介入治疗的STEMI患者82例作为研究对象，按照随机数字表法分为观察组和对照组，各41例。对照组给予常规西医治疗，观察组在对照组基础上加用血必净注射液进行治疗，比较两组PCI术后TIMI血流分级情况、尿微量白蛋白、肝肾功能及超敏C反应蛋白水平。结果 两组TIMI 0级、1级、2级占比比较，差异无统计学意义（P＞0.05）；观察组TIMI 3级占比高于对照组，差异有统计学意义（P＜0.05）。两组PCI术后24 h尿微量白蛋白阳性占比比较，差异无统计学意义（P＞0.05）；观察组术后尿微量白蛋白值低于对照组，差异有统计学意义（P＜0.05）；两组PCI术后72 h肝肾功能比较，差异无统计学意义（P＞0.05）。观察组超敏C反应蛋白水平为（4.54±2.10）mg/L，低于对照组的（5.83±2.68）mg/L，差异有统计学意义（P＜0.05）。结论 STEMI患者应用血必净注射对预防急性心梗介入术后无复流及慢血流有一定作用，能减轻炎症反应，改善冠状动脉微循环的状况，且对肾功能无明显影响。
Abstract:
Objective To investigate the effect of Xuebijing injection in preventing coronary artery no-reflow after direct interventional therapy in patients with acute ST-segment elevation myocardial infarction (STEMI).Methods A total of 82 patients with STEMI who received interventional therapy in our hospital from June 2016 to September 2017 were selected as the research objects. According to the random number table method, they were divided into observation group and control group, with 41 cases in each group. The control group was treated with conventional western medicine, and the observation group was treated with Xuebijing injection on the basis of the control group. The TIMI blood flow classification, urine microalbumin, liver and kidney function, and hypersensitivity C-reactive protein were compared between the two groups after PCI Level.Results There was no significant difference in the proportion of TIMI grade 0, grade 1, and grade 2 between the two groups (P>0.05); the proportion of TIMI grade 3 in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05). There was no statistically significant difference in the percentage of positive urine microalbumin in the two groups at 24 h after PCI (P>0.05); the postoperative urine microalbumin value of the observation group was lower than that of the control group,the difference was statistically significant (P<0.05); There was no significant difference in liver and kidney function 72 h after PCI between the two groups (P>0.05). The level of hypersensitivity C-reactive protein in the observation group was (4.54±2.10) mg/L, which was lower than that of the control group (5.83±2.68) mg/L, the difference was statistically significant (P<0.05).Conclusion Xuebijing injection in STEMI patients had a certain effect on preventing no reflow and slow blood flow after acute myocardial infarction. It could reduce inflammation, improve coronary microcirculation, and had no significant effect on renal function.

参考文献/References:

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更新日期/Last Update: 1900-01-01