[1]许高权.显微外科手术对脑胶质瘤患者认知功能和远期生存率的影响[J].医学信息,2022,35(22):106-108.[doi:10.3969/j.issn.1006-1959.2022.22.022]
　XU Gao-quan.Effect of Microsurgery on Cognitive Function and Long-term Survival Rate in Patients with Glioma[J].Journal of Medical Information,2022,35(22):106-108.[doi:10.3969/j.issn.1006-1959.2022.22.022]
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显微外科手术对脑胶质瘤患者认知功能和远期生存率的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年22期
页码:
106-108
栏目:
论著
出版日期:
2022-11-15

文章信息/Info

Title:
Effect of Microsurgery on Cognitive Function and Long-term Survival Rate in Patients with Glioma
文章编号:
1006-1959（2022）22-0106-03
作者:
许高权
（佳木斯市中心医院神经外科，黑龙江 佳木斯 154002）
Author(s):
XU Gao-quan
(Department of Neurosurgery,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
关键词:
显微外科手术; 脑胶质瘤; 认知功能; 生活能力
Keywords:
Microsurgical; Glioma; Cognitive function; Living ability
分类号:
R739.41
DOI:
10.3969/j.issn.1006-1959.2022.22.022
文献标志码:
A
摘要:
目的 探讨显微外科手术对脑胶质瘤患者认知功能和远期生存率的影响。方法 选取我院2017年3月-2018年5月收治的80例脑胶质瘤患者为研究对象，根据手术方式不同分为研究组与对照组，每组40例。对照组予以常规开颅手术，研究组予以显微外科手术，比较两组手术用时、并发症发生率、术后生活能力、认知功能以及3年内生存率与复发率。结果 研究组手术用时为（60.29±5.07）min，短于对照组的（97.21±10.27）min（P＜0.05）。研究组并发症总发生率为10.00%，低于对照组的37.50%（P＜0.05）；研究组术后1、2、3年生活能力评分、认知功能评分高于对照组（P＜0.05）；研究组与对照组3年内生存率比较，差异无统计学意义（P＞0.05），但研究组复发率低于对照组（P＜0.05）。结论 采用显微外科手术对脑胶质瘤患者进行治疗不仅可以缩短患者的手术时间，而且可以有效改善患者的认知功能以及生活能力，降低复发率，值得临床应用。
Abstract:
Objective To investigate the effect of microsurgery on cognitive function and long-term survival rate in patients with glioma.Methods A total of 80 patients with glioma admitted to our hospital from March 2017 to May 2018 were selected as the research objects. According to different surgical methods, they were divided into study group and control group, with 40 cases in each group. The control group was given routine craniotomy, and the study group was given microsurgery. The operation time, complication rate, postoperative living ability, cognitive function, survival rate and recurrence rate within 3 years were compared between the two groups.Results The operation time of the study group was (60.29±5.07) min, which was shorter than (97.21±10.27) min of the control group (P<0.05). The total incidence of complications in the study group was 10.00%, which was lower than 37.50% in the control group (P<0.05). The scores of life ability and cognitive function in the study group were higher than those in the control group at 1, 2 and 3 years after operation (P<0.05). There was no significant difference in the 3-year survival rate between the study group and the control group (P>0.05), but the recurrence rate of the study group was lower than that of the control group (P<0.05).Conclusion Microsurgical for glioma patients can not only shorten the operation time of patients, but also effectively improve the cognitive function and living ability of patients, reduce the recurrence rate, which is worthy of clinical application.

参考文献/References:

[1]李举军,郭莉娟.显微外科手术联合术后运动想象疗法对脑胶质瘤患者纤溶-凝血指标的影响[J].中国肿瘤临床与康复,2021,28(8):941-944.[2]韩志桐,赵卫平,张瑞剑,等.脑胶质瘤切除术中肿瘤切缘定位中B超的应用价值[J].中华实验外科杂志,2021,38(12):2505-2507.[3]王容杰,杨成义,何雨,等.术前预后营养指数在脑胶质瘤患者术后预后评估中的应用[J].现代肿瘤医学,2021,29(24):4312-4315.[4]茹小红,田志华,申剑波,等.显微镜外科手术治疗脑胶质瘤的近期效果及对认知功能的影响[J].中国临床实用医学,2021,12(2):30-34.[5]龚绍慧,祝新根.显微外科手术对脑胶质瘤患者预后的影响[J].基层医学论坛,2021,25(7):1025,1036.[6]伍碧武,张义,汪洋,等.显微外科手术治疗丘脑胶质瘤及预后分析[J].中华神经外科杂志,2015,31(12):1201-1205.[7]何雨,刘峰,王容杰,等.显微镜下肿瘤切除术对脑胶质瘤患者临床疗效及预后的影响[J].肿瘤预防与治疗,2020,33(12):962-966.[8]郭学军,雷克成,梁勇.显微外科手术治疗脑胶质瘤的临床效果[J].中国临床实用医学,2020,11(6):36-39.[9]田少辉,张学浩,徐江龙,等.miR-194靶向Bmi-1调控PI3K/Akt信号通路对脑胶质瘤细胞迁移和凋亡的影响[J].中国免疫学杂志,2021,37(16):1943-1947.[10]叶诚,毛捷,吴昊,等.显微镜下肿瘤切除对脑胶质瘤患者预后的影响[J].中华全科医学,2019,17(9):1505-1507,1546.[11]Meghdadi N,Soltani M,Niroomand-Oscuii H,Yamani N.Personalized image-based tumor growth prediction in a convection-diffusion-reaction model[J].Acta Neurol Belg,2020,120(1):49-57.[12]Haubold J,Demircioglu A,Gratz M,et al.Non-invasive tumor decoding and phenotyping of cerebral gliomas utilizing multiparametric 18F-FET PET-MRI and MR Fingerprinting[J].Eur J Nucl Med Mol Imaging,2020,47(6):1435-1445.[13]Shymanskaya A,Worthoff WA,Stoffels G,et al.Comparison of [18F]Fluoroethyltyrosine PET and Sodium MRI in Cerebral Gliomas:a Pilot Study[J].Mol Imaging Biol,2020,22(1):198-207.[14]肖学谦,肖三潮,千超,等.显微手术与传统开颅手术对脑胶质瘤患者日常生活 能力及神经肽的影响[J].神经损伤与功能重建,2018,13(8):422-423.[15]黄俊强,周煜,杨立坚.HMGB1在脑胶质瘤中的表达及其对胶质瘤细胞生物学功能的影响[J].现代肿瘤医学,2021,29(2):211-214.[16]Feng E,Liang T,Wang X,et al.Correlation of alteration of HLA-F expression and clinical characterization in 593 brain glioma samples[J].J Neuroinflammation,2019,16(1):33.[17]闫新亭,宋双双,卢洁.脑胶质瘤表观扩散系数与肿瘤分级及IDH1突变的关系[J].首都医科大学学报,2021,42(2):286-292.[18]Kim D,Chun JH,Kim SH,et al.Re-evaluation of the diagnostic performance of 11C-methionine PET/CT according to the 2016 WHO classification of cerebral gliomas[J].Eur J Nucl Med Mol Imaging,2019,46(8):1678-1684.[19]Conte GM,Altabella L,Castellano A,et al.Comparison of T1 mapping and fixed T1 method for dynamic contrast-enhanced MRI perfusion in brain gliomas[J].Eur Radiol,2019,29(7):3467-3479.[20]刘公洪,宋志富,黄小林,等.多模态MRI联合超声显微手术治疗脑胶质瘤临床疗效及预后分析[J].解放军医药杂志,2020,32(7):43-46.

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更新日期/Last Update: 1900-01-01