[1]许高权.立体定向微创手术治疗脑胶质瘤的临床效果及对患者神经功能和日常生活能力的影响[J].医学信息,2022,35(17):76-78.[doi:10.3969/j.issn.1006-1959.2022.17.019]
　XU Gao-quan.The Clinical Effect of Stereotactic Minimally Invasive Surgery in the Treatment of Patients with Glioma and its Influence on Nerve Function and Daily Living Ability[J].Journal of Medical Information,2022,35(17):76-78.[doi:10.3969/j.issn.1006-1959.2022.17.019]
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立体定向微创手术治疗脑胶质瘤的临床效果及对患者神经功能和日常生活能力的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年17期
页码:
76-78
栏目:
论著
出版日期:
2022-09-01

文章信息/Info

Title:
The Clinical Effect of Stereotactic Minimally Invasive Surgery in the Treatment of Patients with Glioma and its Influence on Nerve Function and Daily Living Ability
文章编号:
1006-1959（2022）17-0076-03
作者:
许高权
（佳木斯市中心医院神经外科，黑龙江 佳木斯 154002）
Author(s):
XU Gao-quan
(Department of Neurosurgery,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
关键词:
脑胶质瘤; 微创手术; 神经功能; 日常活动能力; 精氨酸升压素; β-内啡肽
Keywords:
Glioma; Minimally invasive surgery; Nerve function; Daily living ability; Arginine vasopressin; β-endorphin
分类号:
R739.41
DOI:
10.3969/j.issn.1006-1959.2022.17.019
文献标志码:
A
摘要:
目的 评价立体定向微创手术治疗脑胶质瘤患者的临床效果及该术式对患者日常生活能力、神经功能的影响。方法 选取2017年10月-2020年9月在我院神经外科治疗的60例脑胶质瘤患者为研究对象，随机分为微创手术组和对照组，每组30例。对照组采用传统开颅手术治疗，微创手术组采用立体定向微创手术治疗。比较两组手术前、随访1年后脑脊液神经肽指标（精氨酸升压素与β-内啡肽）、日常活动能力量表评分、神经功能缺损程度量表评分、复发率及治疗总有效率。结果 微创手术组精氨酸升压素与β-内啡肽水平均高于对照组，差异有统计学意义（P＜0.05）；微创手术组复发率为0，低于对照组的20.00%，差异有统计学意义（P＜0.05）；微创手术组神经功能缺损程度量表评分低于对照组，日常活动能力量表评分高于对照组，差异有统计学意义（P＜0.05）；微创手术组总有效率为96.67%，高于对照组的76.67%，差异有统计学意义（P＜0.05）。结论 立体定向微创手术治疗脑胶质瘤可改善患者脑脊液神经肽指标，提高临床疗效，降低复发率，有利于患者日常活动能力及神经功能恢复，值得应用。
Abstract:
Objective To evaluate the clinical effect of stereotactic minimally invasive surgery in the treatment of glioma patients and its effect on daily living ability and neurological function.Methods From October 2017 to September 2020,60 patients with glioma treated in neurosurgery department of our hospital were randomly divided into minimally invasive surgery group and control group, with 30 cases in each group. The control group was treated with traditional craniotomy, and the minimally invasive surgery group was treated with stereotactic minimally invasive surgery. The cerebrospinal fluid neuropeptide indexes (arginine vasopressin and β-endorphin)before operation and 1 year after follow-up, daily activity scale score, neurological deficit scale score, recurrence rate and total effective rate of treatment were compared between the two groups.Results The levels of arginine vasopressin and β-endorphin in the minimally invasive surgery group were higher than those in the control group, and the differences were statistically significant (P<0.05). The recurrence rate of the minimally invasive surgery group was 0, which was lower than 20.00% of the control group, and the difference was statistically significant (P<0.05). The score of neurological deficit scale in the minimally invasive surgery group was lower than that in the control group, and the score of daily activity scale was higher than that in the control group, the difference was statistically significant (P<0.05). The total effective rate of the minimally invasive surgery group was 96.67%, which was higher than 76.67% of the control group, and the difference was statistically significant (P<0.05).Conclusion Stereotactic minimally invasive surgery in the treatment of glioma can improve the neuropeptide index of cerebrospinal fluid, improve the clinical efficacy, reduce the recurrence rate, and facilitate the recovery of patients’ daily activities and neurological function, which is worthy of application

参考文献/References:

[1]李航,于佳龙,罗勇,等.肿瘤微血管密度、血管内皮生长因子与缺氧诱导因子-1α在脑胶质瘤中表达及其临床意义[J].中国老年学杂志,2021,41(6):1173-1176.[2]Reifenberger G,Wirsching HG,Knobbe-Thomsen CB,et al.Advances in the molecular genetics of gliomas - implications for classification and therapy[J].Nat Rev Clin Oncol,2017,14(7):434-452.[3]Bai J,Varghese J,Jain R.Adult Glioma WHO Classification Update, Genomics, and Imaging: What the Radiologists Need to Know[J].Top Magn Reson Imaging,2020,29(2):71-82.[4]田艳,魏可欣,张向宁.脑脊液外泌体miR-146a与人脑胶质瘤术后复发的相关性[J].中国临床神经外科杂志,2021,26(4):250-253.[5]Qinglong G,Wei H,Biwu W,et al.Lateral or Medial Surgical Approaches for Thalamic Gliomas Resection?[J].World Neurosurg,2020,136:e90-e107.[6]Sepúlveda-Sánchez JM,Mu?觡oz Langa J,Arráez M?魣,et al.SEOM clinical guideline of diagnosis and management of low-grade glioma (2017)[J].Clin Transl Oncol,2018,20(1):3-15.[7]万涛,马永刚,周新军,等.多模态MRI评估多灶脑胶质瘤影像学特点及播散形态分布的应用研究[J].中国CT和MRI杂志,2021,19(2):35-37.[8]张晓聪,马骏鹏,朱创业,等.脑胶质瘤术后早期癫痫发作相关危险因素的Logistic回归分析[J].肿瘤预防与治疗,2021,34(2):138-142.[9]Noorani I,Sanai N.Surgical Management of Incidental Gliomas[J].Neurosurg Clin N Am,2017,28(3):397-406.[10]Wang J,Yang Y,Liu X,et al.Intraoperative contrast-enhanced ultrasound for cerebral glioma resection and the relationship between microvascular perfusion and microvessel density[J].Clin Neurol Neurosurg,2019,186:105512.[11]高玉杰,周妮娜,李囡,等.11C-MET PET/CT诊断脑胶质瘤术后复发残留的初步研究[J].实用肿瘤杂志,2021,36(2):154-159.[12]张毓,千超,肖三潮,等.超声造影技术和常规超声检查在脑胶质瘤手术切除中的应用比较[J].检验医学与临床,2020,17(8):1121-1124.[13]赵军,吴胜波,李品群,等.立体定向微创手术对脑胶质瘤患者近远期疗效和神经功能评分的影响[J].国际神经病学神经外科学杂志,2020,47(4):387-390.[14]史雪峰,李明兰,韩彦明,等.立体定向脑活检在中枢神经系统疾病诊断中的应用分析[J].宁夏医学杂志,2021,43(8):743-745.[15]刘宏志.立体定向微创手术治疗脑胶质瘤患者的临床效果及对患者Th1/Th2细胞因子的影响[J].实用癌症杂志,2020,35(11):1905-1908.[16]卜雄建,朱峰,刘琨.立体定向微创手术治疗脑胶质瘤的临床疗效分析[J].实用癌症杂志,2018,33(3):389-391.[17]秦峰,黄振超,蔡梅钦,等.立体定向活检对脑干、脑深部疑难病变的精准诊断的价值[J].中华医学杂志,2018,98(22):1771-1774.

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更新日期/Last Update: 1900-01-01