[1]修火琴,陈心铭,吕泽偲,等.艾灸与药物治疗血管性认知障碍疗效的Meta分析[J].医学信息,2023,36(12):32-37.[doi:10.3969/j.issn.1006-1959.2023.12.006]
　XIU Huo-qin,CHEN Xin-ming,LYU Ze-cai,et al.Meta-analysis of the Efficacy of Moxa-wool Moxibustion and Drug Treatment in the Treatment of Vascular Cognitive Impairment[J].Journal of Medical Information,2023,36(12):32-37.[doi:10.3969/j.issn.1006-1959.2023.12.006]
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艾灸与药物治疗血管性认知障碍疗效的Meta分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年12期
页码:
32-37
栏目:
医学数据科学
出版日期:
2023-06-15

文章信息/Info

Title:
Meta-analysis of the Efficacy of Moxa-wool Moxibustion and Drug Treatment in the Treatment of Vascular Cognitive Impairment
文章编号:
1006-1959（2023）12-0032-06
作者:
修火琴; 陈心铭; 吕泽偲; 等
（福建中医药大学护理学院，福建 福州 350122）
Author(s):
XIU Huo-qin; CHEN Xin-ming; LYU Ze-cai; et al.
(School of Nursing,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,Fujian,China)
关键词:
艾灸; 药物治疗; 血管性认知障碍
Keywords:
Moxa-wool moxibustion; Drug treatment; Vascular cognitive impairment
分类号:
R749.13；R245.82
DOI:
10.3969/j.issn.1006-1959.2023.12.006
文献标志码:
A
摘要:
目的 通过系统评价比较艾灸与药物治疗对血管性认知障碍（VCI）的疗效。方法 计算机检索万方、CNKI、维普、中国生物医学文献、PubMed、Embase、Web of Science、Cochrane Library、EBSCO、OVID数据库中艾灸与药物治疗血管性认知障碍疗效比较的临床随机对照试验，检索时间截至2021年10月，将最终纳入的文献参考Cochrane系统评价手册中的文献质量评价标准对纳入文献进行质量评价，并用RevMan5.4软件对相关结局指标进行Meta分析。结果 共纳入10篇文献，涉及569例血管性认知障碍患者，其中艾灸组284例，药物治疗组285例；Meta分析显示，艾灸组认知功能的简易智能精神状态检查量表评分[MD=3.13，95%CI（1.95，4.31），P＜0.000 01]、长谷川痴呆量表评分[MD=3.44，95%CI（1.70，5.19），P=0.0001]，日常生活活动能力的Barthel指数评分[MD=7.50，95%CI（4.12，10.89），P＜0.0001]及总有效率[OR=3.50，95%CI（2.19，5.59），P＜0.000 01]高于药物治疗组，艾灸组的日常生活能力量表评分[MD=-6.05，95%CI（-8.38，-3.71），P＜0.000 01]低于药物治疗组；10篇文献均未见艾灸治疗血管性认知障碍不良反应的相关描述，可见艾灸治疗的安全性较高。结论 与药物相比，艾灸能更好地改善血管性认知障碍患者的认知功能，促进日常生活活动能力的恢复，临床疗效显著。
Abstract:
Objective To compare the efficacy of moxa-wool moxibustion and drug treatment on vascular cognitive impairment (VCI) by systematic review.Methods Randomized controlled trials ( RCTs ) comparing the efficacy of moxa-wool moxibustion and drug treatment in the treatment of vascular cognitive impairment were retrieved from Wanfang, CNKI, VIP, Chinese biomedical literature, PubMed, Embase, Web of Science, Cochrane Library, EBSCO and OVID databases. The retrieval time was up to October 2021. The quality of the included literature was evaluated by referring to the literature quality evaluation criteria in the Cochrane systematic evaluation manual. Meta-analysis of relevant outcome indicators was performed using RevMan5.4 software.Results A total of 10 studies were included, involving 569 patients with vascular cognitive impairment, while 284 patients in the moxa-wool moxibustion group and 285 patients in the drug treatment group. Meta-analysis results showed that the cognitive function of the Mini-mental State Examination [MD=3.13, 95%CI(1.95, 4.31), P<0.000 01], Hasegawa Dementia Scale [MD=3.44, 95%CI(1.70, 5.19), P=0.0001], the activity of daily living of Barthel Index [MD=7.50, 95%CI(4.12, 10.89), P<0.0001] and total effective rate [OR=3.50,95%CI(2.19, 5.59), P<0.000 01] in the moxa-wool moxibustion group were higher than those in the drug treatment group; the daily living ability scale score of the moxa-wool moxibustion group [MD=-6.05, 95%CI(-8.38, -3.71), P<0.000 01] was lower than that of the drug treatment group; there were no related descriptions of adverse reactions of moxibustion in the treatment of vascular cognitive impairment in 10 studies, indicating that the safety of moxa-wool moxibustion treatment was high.Conclusion Compared with drug treatment, moxa-wool moxibustion can better improve the cognitive function of patients with vascular cognitive impairment, promote the recovery of activities of daily living, and has a significant clinical effect.

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更新日期/Last Update: 1900-01-01