[1]单文文,张红霞,姜贵贤.重复经颅磁刺激预防慢性偏头痛的临床疗效和安全性的Meta分析[J].医学信息,2024,37(09):48-53.[doi:10.3969/j.issn.1006-1959.2024.09.008]
 SHAN Wen-wen,ZHANG Hong-xia,JIANG Gui-xian.Meta-analysis of the Clinical Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation in the Prevention of Chronic Migraine[J].Journal of Medical Information,2024,37(09):48-53.[doi:10.3969/j.issn.1006-1959.2024.09.008]
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重复经颅磁刺激预防慢性偏头痛的临床疗效和安全性的Meta分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年09期
页码:
48-53
栏目:
医学数据科学
出版日期:
2024-05-01

文章信息/Info

Title:
Meta-analysis of the Clinical Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation in the Prevention of Chronic Migraine
文章编号:
1006-1959(2024)09-0048-06
作者:
单文文张红霞姜贵贤
(济南市历下区第三人民医院内科,山东 济南 250100)
Author(s):
SHAN Wen-wenZHANG Hong-xiaJIANG Gui-xian
(Department of Internal Medicine,the Third People’s Hospital of Lixia District,Jinan 250100,Shandong,China)
关键词:
重复经颅磁刺激慢性偏头痛预防性治疗
Keywords:
Repetitive transcranial magnetic stimulationChronic migraineProphylactic treatment
分类号:
R747.2
DOI:
10.3969/j.issn.1006-1959.2024.09.008
文献标志码:
A
摘要:
目的 系统性分析重复经颅磁刺激(rTMS)预防慢性偏头痛的临床疗效和安全性。方法 系统检索中国知网、万方医学网、维普中文科技期刊数据库、PubMed、EMBASE和Cochrane图书馆,检索的文献时间截至2023年1月。纳入经颅磁刺激对比假磁刺激预防慢性偏头痛的随机对照实验(RCTs)。采用RevMan5.3软件进行统计分析。结果 共纳入4项RCT研究,包含83例慢性偏头痛患者。Meta分析结果显示rTMS可降低慢性偏头痛患者头痛发作频率(n=83,MD=-7.72,95%CI:-14.00~-1.45,Z=2.41,P=0.02),并减少慢性偏头痛患者的急性止痛药物使用频率(n=69,MD=-8.93,95%CI:-17.55~-0.32,Z=2.03,P=0.04),但不能显著降低患者偏头痛残疾评分(MIDAS)(n=32,MD=-2.94,95%CI:-15.31~9.43,Z=0.47,P=0.64)。rTMS不良反应均为轻中度,患者耐受性良好,具有较高的安全性。结论 rTMS能有效减少慢性偏头痛患者头痛发作频率及急性止痛药物使用频率,不良反应较少。
Abstract:
Objective To systematically analyze the clinical efficacy and safety of repetitive transcranial magnetic stimulation in the prevention of chronic migraine.Methods A computer search was conducted on Chinese National Knowledge Infrastructure, Wanfang Med Online, VIP Chinese Science and Technology Journal Database, PubMed, EMBASE and Cochrane Library were systematically searched until January 2023. The randomized controlled trial (RCT) of transcranial magnetic stimulation versus sham magnetic stimulation for the prevention of chronic migraine were included. RevMan5.3 software was used for statistical analysis.Results A total of 4 RCT studies involving 83 patients with chronic migraine were included. The results of Meta-analysis showed that repetitive transcranial magnetic stimulation could reduce the frequency of headache attacks in patients with chronic migraine (n=83, MD=-7.72, 95%CI:-14.00 to -1.45,Z=2.41,P=0.02), and reduce the frequency of acute analgesic use in patients with chronic migraine (n=69, MD=-8.93,95%CI:-17.55 to -0.32,Z=2.03,P=0.04). However, it could not significantly reduce the Migraine Disability Assessment questionnaire (MIDAS) (n=32, MD=-2.94,95%CI: -15.31 to 9.43,Z=0.47,P=0.64). The adverse reactions of rTMS were mild to moderate, and the patients were well tolerated and had high safety.Conclusion Repetitive transcranial magnetic stimulation can effectively decrease the frequency of headache attacks and the frequency of acute analgesic drug use in patients with chronic migraine, with fewer adverse reactions.

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更新日期/Last Update: 1900-01-01