[1]颜水平,黄丽珍,庄翔莉,等.MicroRNA在过敏性疾病中的研究进展[J].医学信息,2026,39(10):27-31.[doi:10.3969/j.issn.1006-1959.2026.10.004]
　YAN Shuiping,HUANG Lizhen,ZHUANG Xiangli,et al.Research Progress of MicroRNA in Allergic Diseases[J].Journal of Medical Information,2026,39(10):27-31.[doi:10.3969/j.issn.1006-1959.2026.10.004]
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MicroRNA在过敏性疾病中的研究进展()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
39卷
期数:
2026年10期
页码:
27-31
栏目:
生物信息学
出版日期:
2026-05-15

文章信息/Info

Title:
Research Progress of MicroRNA in Allergic Diseases
文章编号:
1006-1959（2026）10-0027-05
作者:
颜水平1; 黄丽珍2; 庄翔莉3; 谢小强4; 喻闽凤1
1.深圳市中医院儿科，广东 深圳 518033；2.广州中医药大学深圳医院儿科，广东 深圳 518034；3.福建中医药大学附属人民医院儿科，福建 福州 350122；4.霞浦县中医院儿科，福建 霞浦 355199
Author(s):
YAN Shuiping1;  HUANG Lizhen2;  ZHUANG Xiangli3;  XIE Xiaoqiang4;  YU Minfeng1
1.Department of Pediatrics, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China;2.Department of Pediatrics, Guangzhou University of Chinese Medicine-Shenzhen Hospital, Shenzhen 518034, Guangdong, China;3.Department of Pediatrics, People′s Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350122, Fujian, China;4.Department of Pediatrics, Xiapu County Traditional Chinese Medicine Hospital, Xiapu 355199, Fujian, China
关键词:
微小RNA; 过敏性疾病; 过敏性鼻炎; 过敏性哮喘; 特应性皮炎; 治疗靶点
Keywords:
MicroRNA;  Allergic diseases;  Allergic rhinitis;  Allergic asthma;  Atopic dermatitis;  Therapeutic target
分类号:
R593
DOI:
10.3969/j.issn.1006-1959.2026.10.004
文献标志码:
A
摘要:
近年来，过敏性疾病的发病率逐年增加，深入研究过敏性疾病的发病机制，并开发治疗过敏性疾病的新型制剂已是当务之急。微小非编码RNA（miRNA）是关键的转录后调节剂，控制许多细胞途径，并在多种免疫学环境中充当关键的调节元件，在T细胞发育和分化的各个阶段起到重要的调节作用。近年研究发现，miRNA在过敏性疾病的发病机制中起着重要作用，本文总结了miRNA在过敏性鼻炎、过敏性哮喘、特应性皮炎中的调节机制，分析其减轻过敏反应来改善疾病症状的作用机制，以期阐明特异性miRNA有望成为过敏性疾病诊断标志物及潜在治疗靶点。
Abstract:
In recent years, the incidence of allergic diseases has increased year by year, so it is urgent to study the pathogenesis of allergic diseases and develop new preparations for the treatment of allergic diseases. MicroRNA (miRNA) is a key post-transcriptional regulator, which controls many cellular pathways and acts as a key regulatory element in various immunological environments, and plays an important role in regulating the development and differentiation of T cells. Recent studies have found that miRNA plays an important role in the pathogenesis of allergic diseases. In this paper, the regulatory mechanisms of miRNA on allergic rhinitis, allergic asthma and atopic dermatitis in recent years are summarized, and the mechanism of reducing allergic reactions and improving disease symptoms is analyzed, in order to demonstrate that specific miRNA is expected to become a diagnostic marker and potential therapeutic target of allergic diseases.

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更新日期/Last Update: 1900-01-01