参考文献/References:
[1]Dwyer-Lindgren L,Bertozzi-Villa A,Stubbs RW,et al.Trends and patterns of differences in chronic respiratory disease mortality among us counties,1980-2014[J].JAM,2017,318(12):1136-1149.
[2]GBD 2015 Mortality and Causes of Death Collaborators.Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015:a systematic analysis for the Global Burden of Disease Study 2015[J].Lancet,2016,388(10053):1459-1544.
[3]Roth-Walter F,Adcock IM,Benito-Villalvilla C,et al.Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper[J].Allergy,2018,74(3):432-448.
[4]林江涛.“重症哮喘诊断和处理中国专家共识”中的中国专家智慧[J].中华结核和呼吸杂志,2017,40(11):803-805.
[5]Wenzel SE.Asthma:defining of the persistent adult phenotypes[J].Lancet,2006,368(9537):804-813.
[6]Molano-Gonzalez N,Rojas M,Monsalve DM,et al.Cluster analysis of autoimmune rheumatic diseases based on autoantibodies.New insights for polyautoimmunity[J].J Autoimmun,2019(98):24-32.
[7]Jurlin L,Greguric T,Baudoin T,et al.Cluster analysis of chronic rhinosinusitis suggests gender-based differences[J].ORL J Otorhinolaryngol Relat Spec,2018,81(1):1-9.
[8]Mirza S,Benzo R.Chronic obstructive pulmonary disease phenotypes: implications for care[J].Mayo Clin Proc,2017,92(7):1104-1112.
[9]Kim MA,Shin SW,Park JS,et al.Clinical characteristics of exacerbation-prone adult asthmatics identified by cluster analysis[J].Allergy,Asthma & Immunology Research,2017,9(6):483-490.
[10]Guan WJ,Jiang M,Gao YH,et al.Unsupervised learning technique identifies bronchiectasis phenotypes with distinct clinical characteristics[J].Int J Tuberc Lung Dis,2016,20(3):402-410.
[11]Fahy JV.Identifying clinical phenotypes of asthma: steps in the right direction[J].Am J Respir Crit Care Med,2010,181(4):296-297.
[12]巩璇,马建伟,董静,等.基于聚类分析的2型糖尿病中医证候规律研究[J].解放军医药杂志,2015,27(9):24-29.
[13]Haghighi B,Choi S,Choi J,et al.Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics:the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)[J].Respiratory Research,2018,19(1):178.
[14]Gomez-Cabrero D,Menche J,Vargas C,et al.From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration[J].BMC Bioinformatics,2016,17(Suppl 15):441.
[15]Hirai K,Shirai T,Suzuki M,et al.A clustering approach to identify and characterize the asthma and chronic obstructive pulmonary disease overlap phenotype[J].Clin Exp Allergy,2017,47(11):1374-1382.
[16]Rabe KF,Hurd S,Anzueto A,et al.Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease:GOLD executive summary[J].Am J Respir Crit Care Med,2007,176(6):532-555.
[17]Cohen JS,Miles MC,Donohue JF,et al.Dual therapy strategies for COPD: the scientific rationale for LAMA+LABA[J].Int J Chron Obstruct Pulmon Dis,2016(11):785-797.
[18]Snoeck-Stroband JB,Lapperre TS,Sterk PJ,et al.Prediction of long-term benefits of inhaled steroids by phenotypic markers in moderate-to-severe COPD:A randomized controlled trial[J].PloS One,2015,10(12):e0143793.
[19]陈建,王广发.慢性阻塞性肺疾病全球倡议2011修订版解读[J].中国医学前沿杂志（电子版）,2012,4(1):42-44.
[20]Burgel PR,Paillasseur JL,Caillaud D,et al.Clinical COPD phenotypes: a novel approach using principal component and cluster analyses[J].Eur Respir J,2010,36(3):531-539.
[21]Pinto LM,Alghamdi M,Benedetti A,et al.Derivation and validation of clinical phenotypes for COPD:a systematic review[J].Respir Res,2015(16):50.
[22]Miravitlles M,Soler-Cataluna JJ,Calle M,et al.Treatment of COPD by clinical phenotypes:putting old evidence into clinical practice[J].Eur Respir J,2013,41(6):1252-1256.
[23]Miravitlles M,Calle M,Soler-Cataluna JJ.Clinical phenotypes of COPD:identification,definition and implications for guidelines[J].Arch Bronconeumol,2012,48(3):86-98.
[24]马洪明,刘晓妍,陈秋冬,等.慢性阻塞性肺疾病的临床表型[J].广东医学,2016,37(5):720-724.
[25]Kilk K,Aug A,Ottas A,et al.Phenotyping of chronic obstructive pulmonary disease based on the integration of metabolomes and clinical characteristics[J].Int J Mol Sci,2018,19(3):E666.
[26]Raherison C,Ouaalaya EH,Bernady A,et al.Comorbidities and COPD severity in a clinic-based cohort[J].BMC Pulmonary Medicine,2018,18(1):117.
[27]梁振宇.关注哮喘的个体化治疗:从表型到内因型[J].中华医学杂志,2015,95(38):3099-3102.
[28]中华医学会.支气管哮喘基层诊疗指南(2018年)[J].中华全科医师杂志,2018,10(17):751-762.
[29]宁璞,郭岩斐,孙铁英,等.系统聚类分析探讨老年人呼吸道疾病的临床表型[J].中华老年医学杂志,2016,3(35):256-259.
[30]Ilmarinen P,Tuomisto LE,Niemela O,et al.Cluster analysis on longitudinal data of patients with adult-onset asthma[J].J Allergy Clin Immunol,2017,5(4):967-978.
[31]Moore WC,Meyers DA,Wenzel SE,et al.Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program[J].Am J Respir Crit Care Med,2010,181(4):315-323.
[32]Serrano-Pariente J,Rodrigo G,Fiz JA,et al.Identification and characterization of near-fatal asthma phenotypes by cluster analysis[J].Allergy,2015,70(9):1139-1147.
[33]Sendin-Hernandez MP,Avila-Zarza C,Sanz C,et al.Cluster analysis identifies 3 phenotypes within allergic asthma[J].J Allergy Clin Immunol Pract,2018,6(3):955-961.
[34]徐金富,林洁璐,瞿介明.中国支气管扩张症诊治现状及面临的挑战[J].中华结核和呼吸杂志,2017,40(1):8-10.
[35]成人支气管扩张症诊治专家共识编写组.成人支气管扩张症诊治专家共识[J].中华结核和呼吸杂志.2012,35(7):485-492.
[36]Martinez-Garcia MA,Miravitlles M.Bronchiectasis in COPD patients: more than a comorbidity?[J].Int J Chron Obstruct Pulmon Dis,2017(12):1401-1411.
[37]Aliberti S,Lonni S,Dore S,et al.Clinical phenotypes in adult patients with bronchiectasis[J].Eur Respir J,2016,47(4):1113-1122.
[38]Adegunsoye A,Oldham JM,Chung JH,et al.Phenotypic clusters predict outcomes in a longitudinal interstitial lung disease cohort[J].Chest,2018,153(2):349-360.
[39]Wang Y,Yella J,Chen J,et al.Unsupervised gene expression analyses identify IPF-severity correlated signatures, associated genes and biomarkers[J].BMC Pulm Med,2017,17(1):133.
[40]Denning DW,Riniotis K,Dobrashian R,et al.Chronic cavitary and fibrosing pulmonary and pleural aspergillosis: case series, proposed nomenclature change, and review[J].Clin Infect Dis,2003,37(Suppl 3):S265-S280.
[41]Ohba H,Miwa S,Shirai M,et al.Clinical characteristics and prognosis of chronic pulmonary aspergillosis[J].Respir Med,2012,106(5):724-729.
[42]Godet C,Laurent F,Beraud G,et al.Phenotyping chronic pulmonary aspergillosis by cluster analysis[J].Eur Respir J,2015,46(5):1509-1512.
相似文献/References:
[1]刘 宇,韩 雪.基于聚类分析的理气药对挖掘[J].医学信息,2019,32(03):10.[doi:10.3969/j.issn.1006-1959.2019.03.004]
LIU Yu,HAN Xue.Drug Pairs Mining of Regulating Qi Based on Cluster Analysis[J].Journal of Medical Information,2019,32(07):10.[doi:10.3969/j.issn.1006-1959.2019.03.004]
[2]曾 频,雷佳芳,刘晓姝,等.基于词频分析透视近十年国内PICC研究[J].医学信息,2019,32(03):19.[doi:10.3969/j.issn.1006-1959.2019.03.007]
ZENG Pin,LEI Jia-fang,LIU Xiao-shu,et al.Perspective of Domestic PICC Research in the Past Ten Years Based on Word Frequency Analysis[J].Journal of Medical Information,2019,32(07):19.[doi:10.3969/j.issn.1006-1959.2019.03.007]
[3]张 毅,周 进.半夏泻心汤临床案例用药量的聚类分析[J].医学信息,2018,31(17):140.[doi:10.3969/j.issn.1006-1959.2018.17.044]
ZHANG Yi,ZHOU Jin.Cluster Analysis of the Dosage of Banxia Xiexin Decoction in Clinical Cases[J].Journal of Medical Information,2018,31(07):140.[doi:10.3969/j.issn.1006-1959.2018.17.044]
[4]黄俊杰,曹立幸,陈 浩,等.基于聚类和关联规则的中医治疗月经先期用药规律探讨[J].医学信息,2018,31(23):1.[doi:10.3969/j.issn.1006-1959.2018.23.001]
HUANG Jun-jie,CAO Li-xing,CHEN Hao,et al.Discussion of the Rule of Traditional Chinese Medicine in the Treatment of Preceeded Menorrhea Based on Clustering and Association Rules[J].Journal of Medical Information,2018,31(07):1.[doi:10.3969/j.issn.1006-1959.2018.23.001]
[5]刘逢源,朱蕙霞,李 锋.国内智慧课堂研究热点透视及对医学教育领域启示[J].医学信息,2019,32(16):1.[doi:10.3969/j.issn.1006-1959.2019.16.001]
LIU Feng-yuan,ZHU Hui-xia,LI Feng.Perspectives on the Hot Spots of Domestic Wisdom Classrooms Research and
Its Implications for Medical Education[J].Journal of Medical Information,2019,32(07):1.[doi:10.3969/j.issn.1006-1959.2019.16.001]
[6]李 娜,关 红,王丽娜.2007~2017年国外社区护理研究文献计量学分析[J].医学信息,2020,33(03):24.[doi:10.3969/j.issn.1006-1959.2020.03.007]
LI Na,GUAN Hong,WANG Li-na,et al.Bibliometric Analysis of Foreign Community Nursing Research From 2007~2017[J].Journal of Medical Information,2020,33(07):24.[doi:10.3969/j.issn.1006-1959.2020.03.007]
[7]周方圆,袁梦露.基于文献计量学的国内手机依赖研究现状和热点分析[J].医学信息,2020,33(08):1.[doi:10.3969/j.issn.1006-1959.2020.08.001]
ZHOU Fang-yuan,YUAN Meng-lu.Analysis of Current Status and Hot Spots of Domestic Mobile Phone Dependence Research Based on Bibliometrics[J].Journal of Medical Information,2020,33(07):1.[doi:10.3969/j.issn.1006-1959.2020.08.001]
[8]姜荣荣,李娉婷,杨 涛.基于无监督学习的心系疾病核心症状群提取研究[J].医学信息,2022,35(20):1.[doi:10.3969/j.issn.1006-1959.2022.20.001]
JIANG Rong-rong,LI Ping-ting,YANG Tao.Research on Core Symptom Cluster Extraction of Heart Disease Based on Unsupervised Learning[J].Journal of Medical Information,2022,35(07):1.[doi:10.3969/j.issn.1006-1959.2022.20.001]
[9]任 远,吴梦蝶,刘光丽,等.移动医疗研究现状和趋势的文献计量学分析[J].医学信息,2021,34(03):12.[doi:10.3969/j.issn.1006-1959.2021.03.004]
REN Yuan,WU Meng-die,LIU Guang-li,et al.A Bibliometric Analysis of the Current Status and Trends of Mobile Medical Research[J].Journal of Medical Information,2021,34(07):12.[doi:10.3969/j.issn.1006-1959.2021.03.004]
[10]贾 慧,李春梅,彭 鸿,等.基于CiteSpaceV的国内护士情绪智力研究热点知识图谱分析[J].医学信息,2023,36(10):30.[doi:10.3969/j.issn.1006-1959.2023.10.007]
JIA Hui,LI Chun-mei,PENG Hong,et al.Knowledge Mapping Analysis of Domestic Nurses’ Emotional Intelligence Research Hotspots Based on CiteSpaceV[J].Journal of Medical Information,2023,36(07):30.[doi:10.3969/j.issn.1006-1959.2023.10.007]