[1]齐尚忠,张 强.低位直肠癌前切除综合征的发病机制及防治研究[J].医学信息,2019,(20):37-39,44.[doi:10.3969/j.issn.1006-1959.2019.20.011]
 QI Shang-zhong,ZHANG Qiang.Pathogenesis and Prevention of Low Rectal Cancer Anterior Resection Syndrome[J].Medical Information,2019,(20):37-39,44.[doi:10.3969/j.issn.1006-1959.2019.20.011]
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低位直肠癌前切除综合征的发病机制及防治研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年20期
页码:
37-39,44
栏目:
综述
出版日期:
2019-10-15

文章信息/Info

Title:
Pathogenesis and Prevention of Low Rectal Cancer Anterior Resection Syndrome
文章编号:
1006-1959(2019)20-0037-04
作者:
齐尚忠1张 强2
(1.甘肃省武威市凉州区第三人民医院普外科,甘肃 武威 733000;2.上海中医药大学附属岳阳中西医结合医院,上海 200437)
Author(s):
QI Shang-zhong1ZHANG Qiang2
(1.Department of General Surgery,the Third People's Hospital of Liangzhou District,Wuwei 733000,Gansu,China;2.Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China
关键词:
低位前切除综合征发病机制预防中医
Keywords:
Low anterior resection syndromePathogenesisPreventionChinese medicine
分类号:
R735.37
DOI:
10.3969/j.issn.1006-1959.2019.20.011
文献标志码:
A
摘要:
随着直肠癌的发病率不断上升,越来越多的患者选择接受低位直肠肿瘤切除术,术后出现的一系列便频、便急、气便失禁等排便功能障碍称为低位前切除综合征(LARS)。本文通过检索国内外关于LARS的文献,对其发病机制及预防进行研究,同时对其中西医治疗进行综述,旨在为临床诊治LARS提供参考。
Abstract:
As the incidence of rectal cancer continues to rise, more and more patients choose to undergo low rectal tumor resection. Postoperative defecation dysfunction, such as frequent, rapid, and incontinence, is called low anterior resection syndrome (LARS). In this paper, we searched the literature on LARS at home and abroad, studied its pathogenesis and prevention, and reviewed the treatment of Western medicine in order to provide reference for clinical diagnosis and treatment of LARS.

参考文献/References:

[1]中华人民共和国卫生和计划生育委员会医政医管局,中华医学会肿瘤学分会.中国结直肠癌诊疗规范(2017年版)[J].中华外科杂志,2018,56(4):241-258. [2]窦若虚,汪建平.直肠癌术前放疗与吻合口漏及低位前切除综合征的关系[J].中国医刊,2019,54(1):10-15. [3]Temple LK,Bacik J,Savatta SG,et al.The developmentof a validated instrument to evaluate bowel function after sphincterpreserving surgery for rectal cancer[J].Dis Colon Recrum,2005,48(7):1353-1365. [4] Wells CI,Vather R,Chu MJ,et al.Anterior resectionsyndrome-a risk factor analysis[J].J Gastrointestinal Surg,2015,19(2):350-359. [5]Ekkarat P,Boonpipattanapong T,Tantiphlachiva K,et al.Factors determining low anterior resection syndrome after rectal cancer resection: A study in Thai patients[J].Asian Journal of Surgery,2016,39(4):225-231. [6]师博,唐劲,田利军,等.直肠癌患者发生低位前切除综合征的相关危险因素[J].中国现代医学杂志,2019(12):93-96. [7]谢国雄,陈建思.直肠癌患者保肛术后低位前切除综合征及影响因素分析[J].中国临床研究,2018,3(11):59-62. [8]Hamabe A,Ito M,Nishigori H,et al.Preventive effect ofdiverting stoma on anastomotic leakage after laparoscopiclow anterior resection with double stapling technique reconstruction applied based on risk stratification[J].Asian J Endosc Surg,2018,11(3):220-226. [9]Ihnát P,Guňková P,Peteja M,et al.Diverting ileostomyin laparoscopic rectal cancer surgery:high price of protection[J].Surg Endosc,2016,30(11):4809-4816. [10]Chen TY,Wiltink LM,Nout RA,et al.Bowel function 14 years afterpreoperative short-course radiotherapy and total mesorectal excisionfor rectal cancer: report of a multicenter randomized trial[J].ClinColorectal Cancer,2015,14(2):106-114. [11]Bryant CL,Lunniss PJ,Knowles CH,et al.Anterior resection syndrome[J].Lancet Oncol,2012,13(9):e403-e408. [12]Pollack J,Holm T,Cedermark B,et al.Long-term effect of preoperative radiation therapy on anorectal function[J].Dis Colon Rectum,2016,49(3):345-352. [13]Ihnát P,Slívová I,Tulinsky L,et al.Anorectal dysfunction afterlaparoscopic low anterior rectal resection for rectal cancer with andwithout radiotherapy(manometry study)[J].J Surq Oncol,2018,117(4):710-716. [14]Bregendahl S,Emmertsen KJ,Fassov J,et al.Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer[J].Radiother Oncol,2013,108(2):331-336. [15]Moszkowicz D,Alsaid B,Bessede T,et al.Where does pelvicnerve injury occur during rectal surgery for cancer?[J].Colorectal Dis,2011,13(12):1326-1334. [16]Ekkarat P,Boonpipattanapong T,Tantiphlachiva K,et al.Factors determining low anterior resection syndrome after rectal cancer resection:a study in Thai patients[J].Asian J Surg,2016,39(4):225-231. [17]Romaniszyn M,Richter P,Walega P,et al.Low-anterior-resection syndrome. How does neoadjuvant radiotherapy and low resection of the rectum influence the function of anal sphincters in patients with rectal cancer Preliminary results of a functional assessment study[J].Pol Przegl Chir,2012,84(4):177-183. [18]肖亚文.生物反馈联合针灸治疗直肠癌保肛术后排便障碍的研究保肛术后排便障碍的研究[D].广州中医药大学,2017. [19]朱晓明,张卫.低位直肠癌切除术后影响功能因素分析及对策[J].中华结直肠疾病电子杂志,2018,8(3):221-226. [20]王银中,韩朝阳,张艳萍,等.腹腔镜手术治疗中低位直肠癌的疗效分析[J].中国内镜杂志,2016,22(7):31-34. [21]李卫军.腹腔镜与开腹全直肠系膜切除术治疗中低位直肠癌患者的疗效比较[J].广西医科大学学报,2015,32(6):946-948. [22]王洪保,黄美近,何玉峰,等.腹腔镜全系膜切除术联合经肛门内括约肌切除术对超低位直肠癌患者的临床疗效分析[J].黑龙江医药,2018,31(1):153-155. [23]赵泽峰,杨之斌.经肛门拖出式全腔镜直肠前切除术治疗中低位直肠癌效果观察[J].山东医药,2017,57(34):53-55. [24]刘文涵,杜斌斌,闫沛静,等.机器人与腹腔镜直肠癌根治术的近期疗效的回顾性队列研究[J].当代医学,2019,25(13):1-6. [25]郑鹏,冯青阳,许剑民.机器人辅助低位直肠癌手术的优势[J].外科理论与实践,2018,23(5):409-412. [26]Heijden JVD,Thomas G,Caers F,et al.What you should know about the low anterior resection syndrome e Clinical recommendations from a patient perspective[J].European Journal of Surgical Oncology,2018(44):1331-1337. [27]谢玲女,姚晓,温春美,等.直肠癌LARS相关生活质量的质性研究[R].中国杭州:2016浙江省肿瘤外科学术年会暨第二届钱江国际肿瘤外科高峰论坛.2016. [28]李晓洁,杨会举,王华胜,等.侧方内括约肌切开术与经皮后胫神经刺激治疗慢性肛裂的比较性研究[J].医药论坛杂志,2019,40(6):94-96. [29]Maeda Y,Laurberg S,Norton C.Perianal injectable bulking agents astreatment for fecal incontinence in adults[J].Cochrane Database SystRev,2010,12(5):7959. [30]孙桂东,邵万金.成人大便失禁的诊断和治疗[J].临床外科杂志,2018,26(4):313-315. [31]周仲瑛.中医内科学[M].北京:中国中医药出版社,2007:35-236. [32]黄卫国,占煜,陈晓辉,等.补中益气汤治疗脾肾阳虚证腹泻型肠易激综合征疗效观察[J].四川中医,2019,37(1):123-125. [33]杜秀英.肠癌术后应用补中益气汤的临床价值分析[J].中国医药指南,2019,16(6):200-201. [34]王益,洪霞.艾灸结合生物反馈治疗直肠癌Dixon术后腹泻的临床研究[J].中国现代医生,2018,56(19):146-149.

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更新日期/Last Update: 2019-10-15