[1]郑 新,张 颖.慢阻肺患者PSQI评分与NLR、PLR、CRP水平及急性加重频率的相关性[J].医学信息,2020,33(12):103-104.[doi:10.3969/j.issn.1006-1959.2020.12.031]
　ZHENG Xin,ZHANG Ying.Correlation of PSQI Score with NLR,PLR,CRP Level and Frequency of Acute Exacerbation in COPD Patients[J].Medical Information,2020,33(12):103-104.[doi:10.3969/j.issn.1006-1959.2020.12.031]
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慢阻肺患者PSQI评分与NLR、PLR、CRP水平及急性加重频率的相关性()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年12期
页码:
103-104
栏目:
临床研究
出版日期:
2020-06-15

文章信息/Info

Title:
Correlation of PSQI Score with NLR,PLR,CRP Level and Frequency of Acute Exacerbation in COPD Patients
文章编号:
1006-1959（2020）12-0103-02
作者:
郑 新; 张 颖
（佳木斯市中心医院急诊科1，心内一科2，黑龙江 佳木斯 154003）
Author(s):
ZHENG Xin; ZHANG Ying
(Department of Emergency1,Department of Cardiology,Subject One2,Jiamusi Central Hospital,Jiamusi 154003,Heilongjiang,China)
关键词:
慢阻肺; 睡眠质量; 中性粒细胞与淋巴细胞比值; 血小板与淋巴细胞比值; C反应蛋白
Keywords:
COPD; Sleep quality; Neutrophil to lymphocyte ratio; Platelet to lymphocyte ratio; C-reactive protein
分类号:
R563
DOI:
10.3969/j.issn.1006-1959.2020.12.031
文献标志码:
A
摘要:
目的 探讨慢性阻塞性肺疾病（慢阻肺）患者睡眠质量与中性粒细胞与淋巴细胞比值（NLR）、血小板与淋巴细胞比值（PLR）、C反应蛋白（CRP）水平及急性加重频率的相关性。方法 回顾性分析我院2018年3月~2019年2月收治的43例慢阻肺患者的临床资料，根据其是否出现睡眠障碍分为睡眠障碍组（29例）与非睡眠障碍组（14例），比较两组NLR、PLR、CRP水平及急性加重频率，并分析匹兹堡睡眠质量量表（PSQI）评分与NLR、PLR、CRP水平及急性加重频率的相关性。结果 睡眠障碍组NLR、PLR、CRP水平均高于非睡眠障碍组，急性加重频率多于非睡眠障碍组，差异有统计学意义（P＜0.05）； Pearson相关性分析显示，PSQI评分与NLR、PLR、CRP水平及急性加重频率呈正相关（P＜0.05）。结论 慢性阻塞性肺疾病患者睡眠质量与NLR、PLR、CRP水平及急性加重频率存在一定相关性，改善患者炎症因子水平，减少急性期加重频率，有助于改善患者的睡眠质量。
Abstract:
Objective To investigate the sleep quality and neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein (CRP) levels and frequency of acute exacerbations in patients with chronic obstructive pulmonary disease (chronic obstructive pulmonary disease) of relevance.Methods Retrospectively analyzed the clinical data of 43 patients with COPD admitted to our hospital from March 2018 to February 2019, and were divided into sleep disorder group (29 cases) and non-sleep disorder group (14 cases) according to whether they had sleep disorders,compare the levels of NLR, PLR, CRP and frequency of acute exacerbation between the two groups, and analyze the correlation between the Pittsburgh Sleep Quality Scale (PSQI) score and the level of NLR, PLR, CRP and frequency of acute exacerbation.Results The levels of NLR, PLR, and CRP in the sleep disorder group were higher than those in the non-sleep disorder group, and the frequency of acute exacerbations was higher than that in the non-sleep disorder group,the difference was statistically significant (P<0.05); Pearson correlation analysis showed that PSQI scores were correlated with NLR, PLR , CRP level and frequency of acute exacerbation were positively correlated (P<0.05).Conclusion There is a certain correlation between the sleep quality of patients with chronic obstructive pulmonary disease and the level of NLR, PLR, CRP and the frequency of acute exacerbation. It can improve the level of inflammatory factors in patients and reduce the frequency of exacerbations in the acute phase, which can help improve the quality of sleep of patients.

参考文献/References:

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更新日期/Last Update: 1900-01-01