[1]刘 柳,吕风华.原发性高血压患者脉压与左心室肥厚及射血分数保留的心衰的相关性[J].医学信息,2021,34(01):112-115.[doi:10.3969/j.issn.1006-1959.2021.01.029]
　LIU Liu,LYU Feng-hua.Correlation of Pulse Pressure with Left Ventricular Hypertrophy and Heart Failure with Preserved Ejection Fraction in Patients with Essential Hypertension[J].Medical Information,2021,34(01):112-115.[doi:10.3969/j.issn.1006-1959.2021.01.029]
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原发性高血压患者脉压与左心室肥厚及射血分数保留的心衰的相关性()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年01期
页码:
112-115
栏目:
论著
出版日期:
2021-01-01

文章信息/Info

Title:
Correlation of Pulse Pressure with Left Ventricular Hypertrophy and Heart Failure with Preserved Ejection Fraction in Patients with Essential Hypertension
文章编号:
1006-1959（2021）01-0112-04
作者:
刘 柳; 吕风华
（新乡医学院第一附属医院心血管内科，河南 新乡 453003）
Author(s):
LIU Liu; LYU Feng-hua
(Department of Cardiovascular Medicine,the First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453003,Henan,China)
关键词:
原发性高血压; 脉压; 左心室肥厚; 射血分数保留的心衰
Keywords:
Essential hypertension; Pulse pressure; Left ventricular hypertrophy; Heart failure with preserved ejection fraction
分类号:
R544.1
DOI:
10.3969/j.issn.1006-1959.2021.01.029
文献标志码:
A
摘要:
目的 研究原发性高血压患者脉压与左心室肥厚及射血分数保留的心衰的相关性。方法 选取新乡医学院第一附属医院2017年10月~2019年10月就诊的原发性高血压患者103例，依据射血分数保留心衰的诊断标准分为心衰组和单纯高血压组，另将心衰组根据NYHA分级分为Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级，比较两组一般资料、实验室指标、心功能各指标，并分析射血分数保留心衰患者的脉压与心功能各指标相关性分析及心衰组不同NYHA分级患者的脉压。结果 103例患者中心衰组49例，高血压组54例；心衰组与高血压组一般资料与实验室指标比较，差异无统计学意义（P＞0.05）；心衰组脉压、NT-proBNP、LVEDd、LAD、IVST、LVPWT、LVMI均高于高血压组，LVEF、E/A均低于高血压组，差异有统计学意义（P＜0.05）；脉压与BNP、LVMI、NYHA分级间均呈正相关关系（r=0.542、0.415、0.428，P＜0.05），脉压与E/A间呈负相关关系（r=-0.415，P＜0.05）；不同NYHA分级患者脉压比较，差异有统计学意义（P＜0.05），且随心衰程度加重，脉压值增大。结论 脉压与NT-proBNP、LVMI、NYHA分级、E/A密切相关，且随心衰程度的加重，脉压值增大。
Abstract:
Objective To study the correlation between pulse pressure and left ventricular hypertrophy and heart failure with preserved ejection fraction in patients with essential hypertension.Methods A total of 103 patients with primary hypertension who were admitted to the First Affiliated Hospital of Xinxiang Medical University from October 2017 to October 2019 were selected and divided into the heart failure group and the simple hypertension group based on the diagnostic criteria of heart failure preserved by ejection fraction. In addition, the heart failure group was divided into Ⅰ, Ⅱ, Ⅲ, and Ⅳ according to NYHA classification. The general data, laboratory indexes, and various indexes of heart function were compared between the two groups, and the pulse pressure and pulse pressure of patients with heart failure preserved by ejection fraction were analyzed. Correlation analysis of various indexes of heart function and pulse pressure of patients with different NYHA grades in heart failure group.Results There were 49 cases in the central failure group of 103 patients and 54 cases in the hypertension group. There was no significant difference in general data and laboratory indicators between the heart failure group and the hypertension group (P>0.05); the pulse pressure and NT-proBNP in the heart failure group, LVEDd, LAD, IVST, LVPWT, LVMI are all higher than the hypertension group, LVEF, E/A are lower than the hypertension group, the difference was statistically significant (P<0.05); between pulse pressure and BNP, LVMI, NYHA classification All showed a positive correlation (r=0.542, 0.415, 0.428,P＜0.05), and there was a negative correlation between pulse pressure and E/A (r=-0.415,P＜0.05);Compared with patients with different NYHA grades, the difference in pulse pressure was statistically significant (P<0.05), and the pulse pressure value increased with the severity of heart failure.Conclusion Pulse pressure is closely related to NT-proBNP, LVMI, NYHA grade, and E/A, and the pulse pressure value increases with the severity of heart failure.

参考文献/References:

[1]Gazewood JD,Turner PL.Heart Failure with Preserved Ejection Fraction:Diagnosis and Management[J].Am Fam Physician,2017,96(9):582-588. [2]Parikh KS,Sharma K,Fiuzat M,et al.Heart Failure With Preserved Ejection Fraction Expert Panel Report:Current Controversies and Implications for Clinical Trials[J].JACC Heart Fail,2018,6(8):619-632. [3]宫玉榕,赵红佳,翁苓.2型糖尿病合并射血分数正常心力衰竭患者的超声指标与中医证型相关性研究[J].中国中西医结合影像学杂志,2019,17(1):59-62. [4]何显菁.不同射血分数心力衰竭患者临床特征的对比分析[J].实用心脑肺血管病杂志,2019,27(8):96-99. [5]刘娜娜,郭敏.射血分数保留和降低的慢性心力衰竭临床研究[J].中国心血管病研究,2016,14(4):340-344. [6]Heidenreich PA,Albert NM,Allen LA,et al.Forecasting the impact of heart failure in the United States:a policy statement from the American Heart Association[J].Circ Heart Fail,2013,6(3):606-619. [7]Christofaro DGD,Casonatto J,Vanderlei LCM,et al.Relationship between Resting Heart Rate,Blood Pressure and Pulse Pressure in Adolescents[J].Arq Bras Cardiol,2017,108(5):405-410. [8]中华医学会心血管病学分会,中华心血管病杂志编辑委员会.中国心力衰竭诊断和治疗指南2014[J].中华心血管病杂志,2014,42(2):98-122． [9]王俊文,李艳清,王红.脉压的形成机制与临床意义[J].哈尔滨医科大学学报,2010,44(4):413-416. [10]崔露露.脉压的影响因素及其与靶器官损害的研究进展[J].海南医学,2019,30(10):1336-1340. [11]Lam CSP,Voors AA,De BRA,et al.Heart failure with preserved ejection fraction：from mechainsms to therapies[J].European Heart Journal,2018,39(30):2780-2792. [12]Benetos A.Pulse pressure and carduiovacular risk[J].J Hypertensin,1999,5(1):S21-S22. [13]杨扬,赵瑞平.微量白蛋白尿及脉压差与冠心病的相关性[J].包头医学院学报,2017,33(9):8-11. [14]Lovic D,Narayan P,Pittaras A,et al.Left ventricular hypertrophy in athletes and hypertensive patients[J].J Clin Hypertens(Greenwich),2017,19(4):413-417. [15]Puddey IB,Mori TA,Barden AE,et al.Alcohol and Hyperten sion-New Insights and Lingering Controversies[J].Curr Hypertens Rep,2019,21(10):79. [16]Hadaegh F,Shafiee G,Hatami M,et al.Systolic and diastolic blood pressure,mean arterial pressure and pulse pressure for prediction of cardiovascular events and mortality in a Middle Eastern population[J].Blood Press,2012,21(1):12-18.

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更新日期/Last Update: 1900-01-01