[1]张艳冬.化痰祛瘀汤治疗冠心病稳定型心绞痛的疗效及对患者血液流变学的影响[J].医学信息,2021,34(08):165-167.[doi:10.3969/j.issn.1006-1959.2021.08.045]
　ZHANG Yan-dong.Effect of Huatan Quyu Decoction on Stable Angina Pectoris of Coronary Heart Disease and Its Influence on Patients’ Hemorheology[J].Medical Information,2021,34(08):165-167.[doi:10.3969/j.issn.1006-1959.2021.08.045]
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化痰祛瘀汤治疗冠心病稳定型心绞痛的疗效及对患者血液流变学的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年08期
页码:
165-167
栏目:
中医中药
出版日期:
2021-04-15

文章信息/Info

Title:
Effect of Huatan Quyu Decoction on Stable Angina Pectoris of Coronary Heart Disease and Its Influence on Patients’ Hemorheology
文章编号:
1006-1959（2021）08-0165-03
作者:
张艳冬
（天津市河东区中医医院内科，天津 300160）
Author(s):
ZHANG Yan-dong
(Department of Internal Medicine,Hedong District Traditional Chinese Medicine Hospital,Tianjin 300160,China)
关键词:
冠心病稳定型心绞痛; 化痰祛瘀汤; 血液流变学; 血管内皮功能
Keywords:
Coronary heart disease with stable angina pectoris; Huatan Quyu Decoction; Hemorheology;  Vascular endothelial function
分类号:
R256.22
DOI:
10.3969/j.issn.1006-1959.2021.08.045
文献标志码:
A
摘要:
目的 观察化痰祛瘀汤治疗冠心病心绞痛的临床效果，评估其对患者血液流变学的影响。方法 选择2016年7月~2020年7月我院收治的120例确诊为冠心病稳定型心绞痛患者作为研究对象，将其随机分为观察组和对照组，各60例，对照组实施常规西医治疗，观察组给予化痰祛瘀汤治疗，比较两组血脂水平、血液流变学、血管内皮功能改善情况、临床疗效及不良反应。结果 观察组HDL-C高于对照组，TG、LDL-C、TC低于对照组，差异有统计学意义（P＜0.05）；观察组纤维蛋白原、血浆黏度、全血高切黏度及全血低切黏度低于对照组，差异有统计学意义（P＜0.05）；观察组NO和SOD水平高于对照组，ET-1和MDA水平低于对照组，差异有统计学意义（P＜0.05）；观察组治疗总有效率高于对照组，不良反应发生率低于对照组，差异有统计学意义（P＜0.05）。结论 化痰祛瘀汤治疗冠心病稳定型心绞痛疗效确切，可改善患者血脂水平、血液流变学及血管内皮功能，安全性良好，值得临床应用。
Abstract:
Objective To observe the clinical effect of Huatan Quyu Decoction in the treatment of angina pectoris of coronary heart disease, and to evaluate its effect on the hemorheology of patients.Methods A total of 120 patients with stable angina pectoris diagnosed with coronary heart disease who were admitted to our hospital from July 2016 to July 2020 were selected as the research objects. They were randomly divided into observation group and control group, with 60 cases in each group.The control group was treated with conventional western medicine, and the observation group was treated with Huatan Quyu Decoction. The improvement of blood lipid levels, hemorheology, vascular endothelial function, clinical efficacy and adverse reactions were compared between the two groups.Results HDL-C of the observation group was higher than that of the control group, TG, LDL-C, and TC were lower than the control group, the difference was statistically significant (P<0.05);The observation group’s fibrinogen, plasma viscosity, whole blood high-shear viscosity and whole blood low-shear viscosity were lower than those of the control group, the difference was statistically significant (P<0.05);The levels of NO and SOD in the observation group were higher than those in the control group, and the levels of ET-1 and MDA were lower than those in the control group, the difference was statistically significant (P<0.05);The total effective rate of treatment in the observation group was higher than that of the control group, and the incidence of adverse reactions was lower than that of the control group,the difference was statistically significant (P<0.05).Conclusion Huatan Quyu Decoction is effective in treating stable angina pectoris of coronary heart disease. It can improve the blood lipid level, hemorheology and vascular endothelial function of patients. It has good safety and is worthy of clinical application.

参考文献/References:

[1]钟宇锋.自拟化痰祛瘀通脉汤治疗冠心病不稳定性心绞痛的疗效及对Hs-CRP,IL-6的影响[J].内蒙古中医药,2019,38(9):73-75. [2]胡博,田伟.化痰祛瘀汤治疗冠心病稳定型心绞痛疗效及对血脂、血液流变学的影响[J].航空航天医学杂志,2018,29(9):1125-1127. [3]张进.自拟化痰祛瘀通脉汤治疗冠心病不稳定型心绞痛的疗效及对血脂,血液流变学的影响[J].医学理论与实践,2018,31(13):1926-1928. [4]彭木辉.化痰祛瘀汤治疗冠心病稳定型心绞痛的临床疗效及对血脂、血液流变学的影响[J].国医论坛,2019,34(2):24-26. [5]陶贵源.化痰祛瘀汤治疗冠心病稳定型心绞痛疗效及对血脂、血液流变学的影响[J].中国医药指南,2019,17(17):175. [6]王皓霖,石立鹏,杜旭勤,等.化痰祛瘀汤治疗冠心病稳定型心绞痛疗效及对血脂、血液流变学的影响[J].现代中西医结合杂志,2018,27(8):20-23. [7]马洪旭.自拟化痰祛瘀通脉汤治疗冠心病不稳定型心绞痛的疗效及对血脂,血液流变学的影响[J].中国民康医学,2019,31(16):111-112,151. [8]李玉岭.化痰祛瘀汤治疗冠心病稳定型心绞痛临床疗效及血脂分析[J].中医临床研究,2019,11(6):38-40. [9]郎海燕.探讨冠心病不稳定型心绞痛应用化痰祛瘀通脉汤治疗的有效性[J].系统医学,2019,4(5):25-27. [10]蒋长胜.中西医结合治疗冠心病不稳定型心绞痛临床观察[J].实用中医药杂志,2017,33(6):640-642. [11]朱东建.化痰祛瘀通脉汤联合二丁酰环磷腺苷治疗不稳定型心绞痛[J].实用中西医结合临床,2018,18(7):17-19. [12]王荣. 自拟化痰祛瘀通脉汤治疗冠心病不稳定型心绞痛的疗效及对血脂,血液流变学的影响[J].世界中医药,2016(B06):1650-1651. [13]高化强,程晓云,田相同.健脾益气、化痰祛瘀法治疗痰浊瘀阻型稳定型心绞痛的临床观察[J].山东医学高等专科学校学报,2018,40(1):57-61. [14]曹辉,石立鹏,杜旭勤,等.化痰祛瘀汤治疗冠心病心绞痛30例疗效观察[J].湖南中医杂志,2017,33(11):5-7. [15]冯跨,魏俊强.祛瘀生新汤联合利伐沙班预防全膝关节置换术后下肢深静脉血栓的疗效及对血液流变学的影响[J].中华中医药学刊,2018,36(7):1789-1792.

更新日期/Last Update: 1900-01-01