[1]袁文芳,张艳琼.雌激素在妇产疾病中的作用[J].医学信息,2021,34(10):54-58.[doi:10.3969/j.issn.1006-1959.2021.10.015]
 YUAN Wen-fang,ZHANG Yan-qiong.The Role of Estrogen in Obstetrics and Gynecology[J].Medical Information,2021,34(10):54-58.[doi:10.3969/j.issn.1006-1959.2021.10.015]
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雌激素在妇产疾病中的作用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年10期
页码:
54-58
栏目:
综述
出版日期:
2021-05-15

文章信息/Info

Title:
The Role of Estrogen in Obstetrics and Gynecology
文章编号:
1006-1959(2021)10-0054-05
作者:
袁文芳张艳琼
(三峡大学医学院器官纤维化与药物靶向治疗研究所1,生物病原与免疫学系2,湖北 宜昌 443002)
Author(s):
YUAN Wen-fangZHANG Yan-qiong
(Institute of Organ Fibrosis and Drug Targeted Therapy1,Department of Biological Pathogens and Immunology2,School of Medicine,China Three Gorges University,Yichang 443002,Hubei,China)
关键词:
雌激素乳腺癌阴道炎
Keywords:
EstrogenBreast cancerVaginitis
分类号:
R711
DOI:
10.3969/j.issn.1006-1959.2021.10.015
文献标志码:
A
摘要:
雌激素是主要的性激素之一,主要作用于女性生殖系统,在女性青春期、妊娠期及绝经期都具有重要的作用。动态监测孕妇妊娠期雌激素水平可用于评价卵巢和胎盘的功能、预测胎儿宫内状况和早孕期妊娠结局等,为临床妇产科干预提供可靠的依据。乳腺癌是一种常见的女性恶性肿瘤,雌激素可促进乳腺癌细胞的增殖和转移,在乳腺癌发生发展过程中具有重要的作用。目前,对于绝经前激素依赖性乳腺癌主要采用雌激素替代疗法,以雌激素受体为治疗指标。此外,在妇产科领域,雌激素制剂还可以用于治疗低雌激素性功能失调性子宫出血、老年性阴道炎和绝经综合征等。本文就雌二醇、雌三醇、雌四醇概述及雌激素与乳腺癌的关系作一综述,以期为临床治疗提供参考。
Abstract:
Estrogen is one of the main sex hormones. It mainly acts on the female reproductive system and plays an important role in female adolescence, pregnancy and menopause.Dynamic monitoring of estrogen levels in pregnant women during pregnancy can be used to evaluate the function of ovaries and placenta, predict fetal intrauterine conditions and pregnancy outcomes during early pregnancy, etc., and provide reliable basis for clinical obstetrics and gynecology interventions.Breast cancer is a common female malignant tumor. Estrogen can promote the proliferation and metastasis of breast cancer cells, and plays an important role in the occurrence and development of breast cancer.At present, estrogen replacement therapy is mainly used for premenopausal hormone-dependent breast cancer, with estrogen receptor as the treatment index.In addition, in the field of obstetrics and gynecology, estrogen preparations can also be used to treat low-estrogen dysfunctional uterine bleeding, senile vaginitis and menopausal syndrome.This article reviews the overview of estradiol, estriol, estriol and the relationship between estrogen and breast cancer, in order to provide references for clinical treatment.

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