[1]楚冬梅,姚 玲.儿童热性惊厥病因及发病机制分析[J].医学信息,2021,34(17):44-48.[doi:10.3969/j.issn.1006-1959.2021.17.012]
 CHU Dong-mei,YAO Ling.Analysis of the Etiology and Pathogenesis of Febrile Seizures in Children[J].Medical Information,2021,34(17):44-48.[doi:10.3969/j.issn.1006-1959.2021.17.012]
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儿童热性惊厥病因及发病机制分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年17期
页码:
44-48
栏目:
综述
出版日期:
2021-09-01

文章信息/Info

Title:
Analysis of the Etiology and Pathogenesis of Febrile Seizures in Children
文章编号:
1006-1959(2021)17-0044-05
作者:
楚冬梅姚 玲
(天津市第五中心医院儿科,天津 300450)
Author(s):
CHU Dong-meiYAO Ling
(Department of Pediatrics,Tianjin Fifth Central Hospital,Tianjin 300450,China)
关键词:
儿童热性惊厥脑损伤癫痫炎症反应
Keywords:
Febrile seizures in childrenBrain injuryEpilepsyInflammatory response
分类号:
R720.597
DOI:
10.3969/j.issn.1006-1959.2021.17.012
文献标志码:
A
摘要:
儿童热性惊厥(FS)指发病年龄为3个月~5岁,体温在38 ℃以上时突然出现惊厥,排除颅内感染和其他导致惊厥的器质性和代谢性疾病,既往无热惊厥史,即可诊断为热性惊厥。该病多数预后良好,部分患儿可出现脑损伤,继发癫痫。目前其确切的发病机制尚不明确,一般认为其与感染后的炎症反应、血脑屏障通透性增加、体温调定点上移和神经元兴奋性增高等有关。为此,本文对该病病因及发病机制的相关研究做一综述,以期为指导合理治疗、预防脑损伤提供帮助。
Abstract:
Children with febrile seizures (FS) refer to the onset age of 3 months to 5 years old, the sudden appearance of seizures when the body temperature is above 38 ℃, intracranial infection and other organic and metabolic diseases that cause seizures are excluded, and there is no previous fever. A history of convulsions can be diagnosed as febrile convulsions.Most of the disease has a good prognosis, and some children may have brain damage and secondary epilepsy.At present, its exact pathogenesis is not clear. It is generally believed to be related to inflammation after infection, increased permeability of the blood-brain barrier, upward shift of body temperature setting points, and increased neuronal excitability.To this end, this article summarizes the related research on the etiology and pathogenesis of the disease, hoping to provide help to guide reasonable treatment and prevent brain injury.

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更新日期/Last Update: 1900-01-01