[1]刘 弢.鼻内镜手术联合糖皮质激素治疗鼻息肉的疗效及对炎症指标的影响[J].医学信息,2021,34(23):123-125.[doi:10.3969/j.issn.1006-1959.2021.23.036]
　LIU Tao.Effect of Endoscopic Sinus Surgery Combined with Glucocorticoid on Nasal Polyps and its Influence on Inflammatory Indexes[J].Medical Information,2021,34(23):123-125.[doi:10.3969/j.issn.1006-1959.2021.23.036]
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鼻内镜手术联合糖皮质激素治疗鼻息肉的疗效及对炎症指标的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年23期
页码:
123-125
栏目:
论著
出版日期:
2021-12-01

文章信息/Info

Title:
Effect of Endoscopic Sinus Surgery Combined with Glucocorticoid on Nasal Polyps and its Influence on Inflammatory Indexes
文章编号:
1006-1959（2021）23-0123-03
作者:
刘 弢
（泰州市中医院耳鼻咽喉科，江苏 泰州 225300）
Author(s):
LIU Tao
(Department of Otolaryngology,Taizhou Hospital of Traditional Chinese Medicine,Taizhou 225300,Jiangsu,China)
关键词:
鼻内镜; 糖皮质激素; 鼻息肉
Keywords:
Nasal endoscopy; Glucocorticoid; Nasal polyps
分类号:
R765.9
DOI:
10.3969/j.issn.1006-1959.2021.23.036
文献标志码:
A
摘要:
目的 观察鼻内镜手术联合糖皮质激素治疗鼻息肉的临床疗效及对炎症指标的影响。方法 选取2018年10月-2021年2月我院诊治的49例鼻息肉患者为研究对象，采用随机数字表法分为对照组（n=24）和观察组（n=25)。对照组采用单纯鼻内镜手术治疗，观察组采用鼻内镜手术联合糖皮质激素治疗，比较两组临床总有效率、手术指标、炎症指标、SNOT-20评分、VAS评分以及复发率。结果 观察组治疗总有效率为96.00%，高于对照组的83.33%，差异有统计学意义（P＜0.05）；观察组术中出血量、手术时间均小于对照组，差异有统计学意义（P＜0.05）；观察组鼻黏膜嗜酸性粒细胞数、超敏C反应蛋白水平均低于对照组，差异有统计学意义（P＜0.05）；观察组SNOT-20评分、VAS评分均低于对照组，差异有统计学意义（P＜0.05）；随访3个月，观察组复发率为4.00%，低于对照组的16.67%，差异有统计学意义（P＜0.05）。结论 鼻内镜手术联合糖皮质激素治疗鼻息肉的效果理想，可减少术中出血量，缩短手术时间，降低炎症水平，促进鼻腔鼻窦功能恢复，减少疼痛程度，且复发率低。
Abstract:
Objective To observe the clinical effect of nasal endoscopic surgery combined with glucocorticoid in the treatment of nasal polyps and its influence on inflammatory indexes.Methods Forty-nine patients with nasal polyps who were treated in our hospital from October 2018 to February 2021 were selected as the study subjects. They were divided into control group (n=24) and observation group (n=25) by random number table method. The control group was treated with endoscopic sinus surgery alone, and the observation group was treated with endoscopic sinus surgery combined with glucocorticoid. The clinical total effective rate, surgical indexes, inflammatory indexes, SNOT-20 score, VAS score and recurrence rate were compared between the two groups.Results The total effective rate of the observation group was 96.00%, which was higher than 83.33% of the control group, and the difference was statistically significant (P<0.05). The intraoperative blood loss and operation time in the observation group were less than those in the control group, and the differences were statistically significant (P<0.05). The number of eosinophils in nasal mucosa and the level of high-sensitivity C-reactive protein in the observation group were lower than those in the control group (P<0.05). The SNOT-20 score and VAS score of the observation group were lower than those of the control group, and the difference was statistically significant (P<0.05). After 3 months of follow-up, the recurrence rate of the observation group was 4.00%, which was lower than 16.67% of the control group, and the difference was statistically significant (P<0.05).Conclusion Endoscopic sinus surgery combined with glucocorticoid is effective in the treatment of nasal polyps, which can reduce the amount of intraoperative blood loss, shorten the operation time, reduce the level of inflammation, promote the recovery of nasal sinus function, reduce the degree of pain, and the recurrence rate is low.

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更新日期/Last Update: 1900-01-01