[1]张璟琳,汪 虹.lncRNA治疗糖尿病难愈性创面的研究现状[J].医学信息,2022,35(08):21-24.[doi:10.3969/j.issn.1006-1959.2022.08.006]
 ZHANG Jing-Lin,WANG Hong.Research Status of lncRNA in Treatment of Diabetic Refractory Wounds[J].Medical Information,2022,35(08):21-24.[doi:10.3969/j.issn.1006-1959.2022.08.006]
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lncRNA治疗糖尿病难愈性创面的研究现状()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年08期
页码:
21-24
栏目:
综述
出版日期:
2022-04-15

文章信息/Info

Title:
Research Status of lncRNA in Treatment of Diabetic Refractory Wounds
文章编号:
1006-1959(2022)08-0021-04
作者:
张璟琳汪 虹
(昆明医科大学第二附属医院烧伤科/云南省烧伤研究所,云南 昆明 650101)
Author(s):
ZHANG Jing-LinWANG Hong
(Department of Burns,the Second Affiliated Hospital,Kunming Medical University/Burn Institute of Yunnan Province,Kunming 650101,Yunnan,China)
关键词:
长链非编码RNA创面愈合糖尿病难愈性创面
Keywords:
Long non-coding RNAWound healingDiabetic refractory wounds
分类号:
R622+.9;R459.9
DOI:
10.3969/j.issn.1006-1959.2022.08.006
文献标志码:
A
摘要:
糖尿病难愈性创面是糖尿病最常见的并发症之一,创面通常愈合不良,给患者带来沉重的生理、心理负担。lncRNA是一种长度超过200 nt的非编码RNA分子,其作为调控关键基因表达的因子参与糖尿病创面的愈合过程。已有大量研究表明lncRNA参与创面愈合的过程,多种lncRNA可成为治疗糖尿病创面的治疗靶点。本文就lncRNA参与创面愈合的机制、在糖尿病难愈性创面中的研究进展进行综述,以期为糖尿病难愈性创面的治疗提供更好的临床思路。
Abstract:
Diabetic wounds are the most common complications of diabetes. Wounds usually heal poorly, bringing heavy physical and psychological burden to patients. LncRNA is a non-coding RNA molecule with a length of more than 200nt, which participates in the healing process of diabetic wounds as a factor regulating the expression of key genes. A large number of studies have shown that lncRNA are involved in the process of wound healing, and a variety of lncRNA can become therapeutic targets for treating diabetic wounds. In this paper, the mechanism of lncRNA’s involvement in wound healing and research progress in diabetic refractorywounds are reviewed, in order to provide better clinical ideas for the treatment of diabetic refractorywounds.

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更新日期/Last Update: 1900-01-01