[1]曾冬梅.血清中结核分枝杆菌IgG、IgM抗体检测在肺结核诊断中的应用价值[J].医学信息,2022,35(22):157-159.[doi:10.3969/j.issn.1006-1959.2022.22.039]
　ZENG Dong-mei.The Application Value of Serum Mycobacterium Tuberculosis IgG and IgM Antibody Detection in the Diagnosis of Pulmonary Tuberculosis[J].Journal of Medical Information,2022,35(22):157-159.[doi:10.3969/j.issn.1006-1959.2022.22.039]
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血清中结核分枝杆菌IgG、IgM抗体检测在肺结核诊断中的应用价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年22期
页码:
157-159
栏目:
诊疗技术
出版日期:
2022-11-15

文章信息/Info

Title:
The Application Value of Serum Mycobacterium Tuberculosis IgG and IgM Antibody Detection in the Diagnosis of Pulmonary Tuberculosis
文章编号:
1006-1959（2022）22-0157-03
作者:
曾冬梅
（上犹县疾病预防控制中心检验科，江西 上犹 341299）
Author(s):
ZENG Dong-mei
(Department of Laboratory,Shangyou County Center for Disease Control and Prevention,Shangyou 341299,Jiangxi,China)
关键词:
结核分枝杆菌; IgG抗体; IgM抗体; 肺结核
Keywords:
Mycobacterium tuberculosis; IgG antibody; IgM antibody; Tuberculosis
分类号:
R378
DOI:
10.3969/j.issn.1006-1959.2022.22.039
文献标志码:
A
摘要:
目的 研究血清中结核分枝杆菌免疫球蛋白-G（IgG）、免疫球蛋白-M（IgM）抗体检测在肺结核诊断中的应用价值。方法 选取2018年6月-2021年6月上犹县疾病预防控制中心诊治的62例肺结核患者作为肺结核组，另选取同期在本单位健康体检者50例作为对照组，并选取50例潜伏感染患者作为潜伏感染组，比较三组IgG、IgM抗体阳性检出率、IgG、IgM以及IgG联合IgM诊断肺结核的效能。结果 肺结核组结核分枝杆菌IgG、IgM抗体阳性检出率均高于潜伏感染组、对照组，且潜伏感染组高于对照组（P＜0.05）；IgG联合IgM诊断肺结核的敏感度、特异度、准确度、阳性预测值、阴性预测值均高于IgG、IgM单项检测（P＜0.05）。结论 血清中结核分枝杆菌IgG、IgM抗体检测在肺结核诊断中具有较高的应用价值，尤其是两者联合可提高肺结核诊断准确率。
Abstract:
Objective To study the application value of serum tuberculosis immunoglobulin-G (IgG), immunoglobulin-M (IgM) antibody detection in the diagnosis of pulmonary tuberculosis.Methods From June 2018 to June 2021, 62 patients with pulmonary tuberculosis diagnosed and treated by Shangyou County Center for Disease Control and Prevention were selected as the pulmonary tuberculosis group. In addition, 50 healthy people who underwent physical examination in our unit during the same period were selected as the control group, and 50 patients with latent infection were selected as the latent infection group. The positive detection rates of IgG and IgM antibodies, IgG, IgM and IgG combined with IgM in the diagnosis of pulmonary tuberculosis were compared among the three groups.Results The positive detection rates of Mycobacterium tuberculosis IgG and IgM antibodies in the tuberculosis group were higher than those in the latent infection group and the control group, and the latent infection group was higher than the control group (P<0.05). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of IgG combined with IgM in the diagnosis of pulmonary tuberculosis were higher than those of IgG and IgM (P<0.05).Conclusion The detection of Mycobacterium tuberculosis IgG and IgM antibodies in serum has high application value in the diagnosis of pulmonary tuberculosis, especially the combination of the two can improve the diagnostic accuracy of pulmonary tuberculosis.

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更新日期/Last Update: 1900-01-01