[1]徐美丽,王文怡,施雨燕,等.中国类风湿关节炎患者抑郁发病率的Meta分析[J].医学信息,2024,37(03):7-13.[doi:10.3969/j.issn.1006-1959.2024.03.002]
　XU Mei-li,WANG Wen-yi,SHI Yu-yan,et al.Meta-analysis of the Incidence of Depression in Patients with Rheumatoid Arthritis in China[J].Journal of Medical Information,2024,37(03):7-13.[doi:10.3969/j.issn.1006-1959.2024.03.002]
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中国类风湿关节炎患者抑郁发病率的Meta分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年03期
页码:
7-13
栏目:
医学数据科学
出版日期:
2024-02-01

文章信息/Info

Title:
Meta-analysis of the Incidence of Depression in Patients with Rheumatoid Arthritis in China
文章编号:
1006-1959（2024）03-0007-07
作者:
徐美丽; 王文怡; 施雨燕; 等
（1.湖南中医药大学第一附属医院风湿免疫科，湖南 长沙 410007；2.湖南中医药大学护理学院，湖南 长沙 410208）
Author(s):
XU Mei-li; WANG Wen-yi; SHI Yu-yan; et al.
(1.Department of Rheumatology and Immunology,the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410007,Hunan,China;2.Nursing College of Hunan University of Traditional Chinese Medicine,Changsha 410208,Hunan,China)
关键词:
类风湿关节炎; 抑郁; 患病率
Keywords:
Rheumatoid arthritis; Depression; Prevalence
分类号:
R593.22；R749.4+1
DOI:
10.3969/j.issn.1006-1959.2024.03.002
文献标志码:
A
摘要:
目的 了解我国类风湿关节炎患者抑郁发病率，为临床提供参考意见。方法 检索中国知网、万方、维普、中国生物医学文献服务系统、PubMed、MedlineComplete数据库中建库至2023年2月发表的中国类风湿关节炎患者抑郁发病情况的文献。由2名研究者独立筛选文献建立数据库，使用R4.2.2软件进行Meta分析。结果 共纳入40篇文献，8535例类风湿关节炎患者中4075例检出抑郁症状，中国类风湿关节炎患者抑郁发病率44.70%（95%CI：38.90~50.44）；亚组分析结果显示女性患者抑郁发病率[28.52%（95%CI：20.22~38.58）]高于男性[6.78%（95%CI：4.92~9.27）]，差异有统计学意义（P=0.0002）；不同评估工具测得抑郁发生率存在统计学差异（P＜0.0001）。结论 我国类风湿关节炎患者抑郁发病率较高，需要关注患者心理状态，并采取干预措施以提供有效支持。
Abstract:
Objective To understand the incidence of depression in patients with rheumatoid arthritis in China, and to provide reference for clinical practice.Methods The literature on the incidence of depression in patients with rheumatoid arthritis in China published from the establishment of the database to February 2023 was searched in China Knowledge Network Infrastructure, Wanfang, VIP, SinoMed, PubMed and MedlineComplete databases. Two researchers independently screened literature to establish a database, and meta-analysis was performed using R4.2.2 software.Results A total of 40 literatures were included, and 4075 of 8535 patients with rheumatoid arthritis were found to have depressive symptoms. The incidence of depression in Chinese patients with rheumatoid arthritis was 44.70%（95%CI：38.90-50.44）. The results of subgroup analysis showed that the incidence of depression in female patients [28.52%(95%CI:20.22-38.58)] was higher than that in male patients [6.78%(95%CI:4.92-9.27)], and the difference was statistically significant (P=0.0002). There was a statistically significant difference in the incidence of depression measured by different assessment tools (P<0.0001).Conclusion The incidence of depression in patients with rheumatoid arthritis in China is high. It is necessary to pay attention to the psychological state of patients and take intervention measures to provide effective support.

参考文献/References:

[1]朱平,林文棠.临床免疫学[M].北京:高等教育出版社,2011:28.[2]Lisitsina TA,Vel’tishchev DIu,Krasnov VN,et al.Clinical and pathogenetic relationships between immuno-inflammatory rheumatic diseases and psychic disorders[J].Klin Med,2014,92(1):12-21.[3]Hashimoto A,Sato H,Nishibayahi Y,et al.A multicenter cross-sectional study on the health related quality of life of patients with rheumatoid arthritis using a revised Japanese version of the arthritis impact mea-surement scales version 2(AIMS 2),focusing on the medical care costs and their associative factors [J].Ryumachi,2002,42(1):23-39.[4]Leon L,Jover JA,Loza E,et al.Health-related quality of life as a main determinant of access to rheumatologic care[J].Rheumatol Int,2013,33(7):1797-1804.[5]周英凤,顾莺,胡雁,等.JBI循证卫生保健中心对关于不同类型研究的质量评价工具——患病率及分析性横断面研究的质量评价[J].护士进修杂志,2018,33(3):219-221.[6]王永刚,张丽君,舒彬,等.类风湿关节炎患者150例的心理状况[J].职业与健康,2011,27(22):2516-2665.[7]Liu L,Xu N,Wang L.Moderating role of self-efficacy on the associations of social support with depressive and anxiety symptoms in Chinese patients with rheumatoid arthritis[J].Neuropsychiatr Dis Treat,2017,13:2141-2150.[8]郭静波,李亮,杨建乐.类风湿关节炎患者焦虑抑郁调查分析[J].风湿病与关节炎,2012,1(3):28-29,36.[9]潘霞,刘密,陈艳.类风湿关节炎女性患者家庭功能与抑郁情绪的相关性分析[J].护理实践与研究,2016,13(3):109-111.[10]王萌,许磊,邱晓惠,等.应对方式对类风湿性关节炎患者抑郁情绪的影响：希望水平的中介效应模型[J].哈尔滨医科大学学报,2022,56(4):392-396.[11]王敏,郭峰,李国铨,等.海南地区类风湿关节炎患者焦虑抑郁状态及其影响因素调查[J].海南医学,2021,32(4):532-535.[12]谢晶芹,向珊,蔡德慧,等.恩施部分地区老年类风湿关节炎患者抑郁状态的调查分析[J].风湿病与关节炎,2015,4(4):23-24,27.[13]姚血明,马武开,唐芳,等.贵阳市区类风湿关节炎就诊患者抑郁情况调查分析[J].广州中医药大学学报,2011,28(3):222-225.[14]张文皓,张宏晨,刘志琛,等.类风湿关节炎病人焦虑及抑郁情绪与疾病活动度的相关性[J].护理研究,2017,31(27):3424-3426.[15]张子云,汪晖,王霞,等.湖北省类风湿关节炎病人焦虑、抑郁状况及其危险因素[J].护理研究,2021,35(19):3550-3555.[16]Pu D,Luo J,Wang Y,et al.Prevalence of depression and anxiety in rheumatoid arthritis patients and their associations with serum vitamin D level[J].Clin Rheumatol,2018,37(1):179-184.[17]Zhang L,Xia Y,Zhang Q,et al.The correlations of socioeconomic status, disease activity, quality of life, and depression/anxiety in Chinese patients with rheumatoid arthritis[J].Psychol Health Med,2017,22(1):28-36.[18]陈晓,杨敏,王天,等.类风湿关节炎患者抑郁症发生的相关因素分析[J].中华临床医师杂志(电子版),2013(7):2809-2812.[19]戴冽,汤美安,张亚哲,等.类风湿关节炎患者的心理健康状况及个性特征[J].中国行为医学科学,1997(4):34-36.[20]戴微微,冯伟伟,李德富,等.风湿免疫病住院患者的抑郁与自杀风险分析[J].昆明医科大学学报,2022,43(3):160-165.[21]董李湘,李丽君,尤苗,等.类风湿关节炎合并抑郁状态的调查及综合干预[J].中国健康心理学杂志,2013,21(3):348-350.[22]韩晓蕾,石磊.类风湿关节炎患者抑郁情况及与疾病活动度相关性分析[J].中国药物与临床,2019,19(11):1768-1770.[23]黄建林,曾咏梅,肖小琴,等.类风湿关节炎患者焦虑和抑郁调查分析[J].医学理论与实践,2005(11):108-109.[24]姜林娣,季建林,王吉耀,等.类风湿关节炎抑郁情况调查[J].中华风湿病学杂志,1999(3):169-171.[25]姜小帆,曹雯,陈芳,等.类风湿关节炎患者伴焦虑、抑郁状态的分布情况及其与中医证型的相关性[J].世界中西医结合杂志,2021,16(9):1569-1572.[26]康春来,陈晓霞,张兆捷.类风湿关节炎患者抑郁、焦虑状况调查及分析[J].现代中西医结合杂志,2010,19(3):284-285.[27]刘红艳.240例类风湿关节炎患者焦虑、抑郁的心理护理疗效观察[J].风湿病与关节炎,2017,6(11):61-63.[28]刘宏雅.中老年关节炎患者焦虑抑郁状况及干预对策[J].中国老年学杂志,2015,35(14):4021-4022.[29]刘健,杨梅云,范海霞.伴和不伴抑郁症状的类风湿关节炎患者的临床比较研究[J].中国神经精神疾病杂志,2007(7):442-443.[30]马新美,王凌,王继军.类风湿性关节炎患者精神因素的调查分析与干预治疗[J].中国医师杂志,2006(10):1365-1366.[31]帅世全,孙红兵.类风湿关节炎抑郁障碍的临床探讨[J].西部医学,2011,23(8):1551-1552,1555.[32]孙鹏,夏云霞,姬萍.类风湿性关节炎患者关节疼痛与心理状态的相关性调查[J].人民军医,2012,55(11):1086-1087.[33]王敬联,田溢卿,宁晓然,等.类风湿关节炎患者焦虑抑郁情况调查分析[J].疑难病杂志,2006(4):287-288.[34]魏雪敏,张志毅.黑龙江省类风湿关节炎患者焦虑及抑郁症状调查分析[J].哈尔滨医科大学学报,2018,52(4):361-363.[35]吴鸣.老年类风湿关节炎患者抑郁状态调查及护理干预[J].护理实践与研究,2011,8(16):124-125.[36]杨海红,星霞,李雪莹,等.类风湿关节炎患者焦虑及抑郁情绪与疾病活动度的相关性[J].医学信息,2019,32(18):110-111.[37]尹国富,岳敏,聂建平,等.类风湿关节炎患者伴发抑郁症临床调查[J].山东中医杂志,2011,30(10):703-704.[38]张丽丽,石香花,孙仕润.中老年类风湿关节炎患者负面情绪与生活质量的相关性[J].中国老年学杂志,2016,36(16):4037-4038.[39]张仕玉,彭树刚,石欣,等.新型冠状病毒肺炎疫情下风湿病患者的心理状态及干预策略[J].风湿病与关节炎,2020,9(12):23-25,56.[40]张颖,刘健,黄旦,等.135例类风湿关节炎患者感受的变化及其相关性分析[J].风湿病与关节炎,2019,8(11):15-19.[41]张云飞,慈春增,王晓东,等.类风湿关节炎患者发生抑郁的相关因素分析[J].潍坊医学院学报,2017,39(3):233-235.[42]赵浩,薛鸾,施晓芬,胡建东.类风湿关节炎伴抑郁的调查及其相关性的研究[J].中华风湿病学杂志,2005(10):632-633.[43]赵浩,王丹.类风湿关节炎伴发抑郁的中医临床证型分布特点[J].中国中西医结合杂志,2013,33(9):1208-1211.[44]周润华,朱芳晓,王晓桃,等.76例类风湿关节炎患者抑郁症状临床分析[J].重庆医学,2010,39(4):466-468.[45]朱湘竹,蓝绍颖,朱建平,等.类风湿性关节炎患者的心理健康状况调查分析[J].交通医学,2006,20(5):617-618.[46]MatchamF,RaynerL,SteerS,etal.The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis[J].Rheumatology (Oxford),2013,52(12):2136-2148.[47]MargarettenM,YelinE,ImbodenJ,etal.Predictors of depression in a multiethnic cohort of patients with rheumatoid arthritis[J].Arthritis Care & Research,2010,61(11):1586-1591.[48]郑志坚.类风湿关节炎患者焦虑抑郁情绪及其与生活质量的相关性[J].中国临床保健杂志,2010,13(1):9-11.[49]周云杉,王秀茹,安媛,等.全国多中心类风湿关节炎患者残疾及功能受限情况的调查[J].中华风湿病学杂志,2013,17(8):526-532.[50]HowrenMB,LamkinDM,SulsJ.Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis[J].Psychosom Med,2009,71(2):171-186.[51]DowlatiY,HerrmannN,SwardfagerW,etal.A meta-analysis of cytokines in major depression[J].Biol Psychiatry,2010,67(5):446-457.[52]徐学兵,白红娟,田涛.不同性别抑郁症患者自杀风险危险因素研究[J].宁夏医学杂志,2021,43(2):141-144.[53]万秋容,黄雅莲,毛晓雨,等.老年人抑郁现状及影响因素分析[J].中国医药导报,2022,19(8):48-51,63.

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更新日期/Last Update: 1900-01-01