[1]张华雄,李 吉.玫瑰痤疮先天免疫及周围神经相关致病机理研究进展[J].医学信息,2019,32(08):53-57.[doi:10.3969/j.issn.1006-1959.2019.08.017]
　ZHANG Hua-xiong,LI Ji.Research Progress on Innate Immunity and Peripheral Nerve-related Pathogenesis of Rosacea[J].Journal of Medical Information,2019,32(08):53-57.[doi:10.3969/j.issn.1006-1959.2019.08.017]
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玫瑰痤疮先天免疫及周围神经相关致病机理研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年08期
页码:
53-57
栏目:
综述
出版日期:
2019-04-15

文章信息/Info

Title:
Research Progress on Innate Immunity and Peripheral Nerve-related Pathogenesis of Rosacea
文章编号:
1006-1959（2019）08-0053-05
作者:
张华雄1; 李 吉2
（1.新疆医科大学，新疆 乌鲁木齐 830000；2.中南大学湘雅医院皮肤科，湖南 长沙 410008）
Author(s):
ZHANG Hua-xiong1; LI Ji2
(1.Xinjiang Medical University,Urumqi 830000,Xinjiang,China;2.Department of Dermatology,Xiangya Hospital,Central South University,Changsha 410008,Hunan,China)
关键词:
玫瑰痤疮; 免疫; 周围神经; 神经纤维伤害感受器; 离子通道
Keywords:
Rosacea; Immunity; Peripheral nerve; Nerve fiber injury receptor; Ion channel
分类号:
R758.734
DOI:
10.3969/j.issn.1006-1959.2019.08.017
文献标志码:
A
摘要:
玫瑰痤疮是一种常见的面部慢性炎症型皮肤病，其临床特征包含红斑、丘疹、毛细血管扩张、水肿、脓疱等症状，该病发病率高，致病机理复杂。目前已有大量研究证实在机体先天免疫系统和神经系统的功能紊乱及其相互作用参与了玫瑰痤疮的发生发展。本文就参与玫瑰痤疮发病的免疫细胞、神经纤维伤害感受器、离子通道等对玫瑰痤疮的病理生理进程影响的相关研究进行综述。
Abstract:
Rosacea is a common chronic inflammatory skin disease in the face. Its clinical features include erythema papules telangiectasia edema pustule and so on. The incidence of rosacea is high and the pathogenesis ofacnerosacea is complicated. At present, a large number of studies have confirmed that the dysfunction and interaction of innate immune system and nervous system are involved in the occurrence and development of rosacea. The effects of immune cells, nerve fiber injury receptors and ion channels on the pathophysiological process of rosacea were reviewed in this paper.

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更新日期/Last Update: 2019-04-15