[1]曾 涛.2019年某院儿童9项呼吸道病原体IgM抗体检测结果分析[J].医学信息,2021,34(06):150-153.[doi:10.3969/j.issn.1006-1959.2021.06.039]
 ZENG Tao.Analysis of IgM Antibody Test Results of 9 Respiratory Pathogens in Children in a Hospital in 2019[J].Medical Information,2021,34(06):150-153.[doi:10.3969/j.issn.1006-1959.2021.06.039]
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2019年某院儿童9项呼吸道病原体IgM抗体检测结果分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年06期
页码:
150-153
栏目:
调查分析
出版日期:
2021-03-15

文章信息/Info

Title:
Analysis of IgM Antibody Test Results of 9 Respiratory Pathogens in Children in a Hospital in 2019
文章编号:
1006-1959(2021)06-0150-04
作者:
曾 涛
(电子科技大学医学院附属妇女儿童医院·成都市妇女儿童中心医院检验科,四川 成都 611731)
Author(s):
ZENG Tao
(Women and Children’s Hospital Affiliated to School of Medicine,University of Electronic Science and Technology of China·Department of Laboratory Medicine,Chengdu Women and Children’s Central Hospital,Chengdu 611731,Sichuan,China)
关键词:
呼吸道感染病原体儿童IgM抗体
Keywords:
Respiratory tract infectionPathogenChildIgM antibody
分类号:
R725.6
DOI:
10.3969/j.issn.1006-1959.2021.06.039
文献标志码:
A
摘要:
目的 了解我院9项呼吸道病原体IgM抗体在儿童呼吸道感染中的流行情况,分析病原体流行趋势及特点。方法 采用间接免疫荧光法检测2019年1月~12月在我院就诊的19,687例呼吸道感染患儿血清中嗜肺军团菌血清1型(LP1)、肺炎支原体(MP)、Q热立克次体(COX)、肺炎衣原体(CP)、腺病毒(ADV)、呼吸道合胞病毒(RSV)、甲型流感病毒(IFVA)、乙型流感病毒(IFVB)、副流感病毒(PIV)等9项呼吸道病原体的IgM抗体,分析各病原体阳性率及混合感染情况,比较不同性别、年龄、季节患儿的感染情况。结果 病原体检出总阳性5928例,总阳性率为30.11%,其中阳性率最高的3种病原体依次为MP(20.92%)、IFVB(4.79%)和PIV(1.80%);单一病原体感染阳性率为21.58%,2种及2种以上呼吸道病原体混合感染阳性率为3.96%,二联混合感染中MP+IFVB模式最为常见,三联混合感染模式中MP+IFVB+PIV阳性率最高。女性阳性率高于男性,差异有统计学意义(P<0.05);各年龄段内,幼儿(1~3岁)阳性率最高,且各年龄段均以MP感染为主;季节比较,春季阳性率最高(49.44%),其次为冬季(29.83%)。结论 MP、IFVB和PIV是儿童呼吸道感染的主要病原体,混合感染较为普遍;不同性别、年龄、季节病原体的感染具有一定差异。
Abstract:
Objective To understand the prevalence of 9 respiratory pathogen IgM antibodies in children’s respiratory tract infections in our hospital, and analyze the trend and characteristics of pathogens.Methods The indirect immunofluorescence method was used to detect the serum levels of Legionella pneumophila serotype 1 (LP1) in the sera of 19,687 children with respiratory tract infection who were admitted to our hospital from January to December 2019.Mycoplasma pneumonia (MP), Rickettsia Q fever (COX), Chlamydia pneumoniae (CP), adenovirus (ADV), respiratory syncytial virus (RSV), influenza A virus (IFVA), influenza B virus (IFVB), parainfluenza virus (PIV) and other 9 respiratory pathogens IgM antibodies,analyze the positive rate of each pathogen and the mixed infection, and compare the infection of children of different genders, ages, and seasons.Results A total of 5928 pathogens were detected positive, with a total positive rate of 30.11%. The three pathogens with the highest positive rate were MP (20.92%), IFVB (4.79%) and PIV (1.80%);The positive rate of single pathogen infection was 21.58%, the positive rate of mixed infection of two or more respiratory tract pathogens was 3.96%, the MP+IFVB mode was the most common in dual mixed infection, and the MP+IFVB+PIV positive rate was highest in the triple mixed infection.The positive rate of women was higher than that of men,the difference was statistically significant (P<0.05);Among all age groups, children (1 to 3 years old) had the highest positive rate, and MP infection was the main cause of all age groups; compared with seasons, the positive rate was highest in spring (49.44%), followed by winter (29.83%).Conclusion MP, IFVB and PIV are the main pathogens of respiratory tract infections in children, and mixed infections are more common; pathogen infections of different genders, ages, and seasons have certain differences.

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更新日期/Last Update: 1900-01-01