[1]刘 艳.肺结核合并结核性胸膜炎患者血清CA125和铁蛋白检测的临床价值[J].医学信息,2022,35(06):177-179.[doi:10.3969/j.issn.1006-1959.2022.06.047]
　LIU Yan.Clinical Value of Serum CA125 and Ferritin in Patients with Pulmonary Tuberculosis Complicated with Tuberculous Pleurisy[J].Medical Information,2022,35(06):177-179.[doi:10.3969/j.issn.1006-1959.2022.06.047]
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肺结核合并结核性胸膜炎患者血清CA125和铁蛋白检测的临床价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年06期
页码:
177-179
栏目:
诊疗技术
出版日期:
2022-03-15

文章信息/Info

Title:
Clinical Value of Serum CA125 and Ferritin in Patients with Pulmonary Tuberculosis Complicated with Tuberculous Pleurisy
文章编号:
1006-1959（2022）06-0177-03
作者:
刘 艳
（佳木斯市结核病防治院检验科，黑龙江 佳木斯 154002）
Author(s):
LIU Yan
(Department of Laboratory,Jiamusi Tuberculosis Prevention Hospital,Jiamusi 154002,China)
关键词:
肺结核; 结核性胸膜炎; CA125; 铁蛋白
Keywords:
Tuberculosis; Tuberculous pleurisy; CA125; Ferritin
分类号:
R521.7
DOI:
10.3969/j.issn.1006-1959.2022.06.047
文献标志码:
A
摘要:
目的 研究肺结核合并结核性胸膜炎患者血清糖类抗原125（CA125）和血清铁蛋白（SF）检测的临床价值。方法 选取2020年4月-2021年5月在我院诊治的126例肺结核患者为研究对象。依据肺实质病变是否累及胸膜分为肺结核组34例，合并组92例（肺结核合并结核性胸膜炎）。另选取同期体检健康者30例设为对照组，比较3组血清CA125和SF水平、不同类型肺结核合并结核性胸膜炎患者CA125和SF水平，以及CA125、SF与CA125联合SF检测肺结核合并结核性胸膜炎的敏感度、特异度以及准确度。结果 合并组血清CA125、SF均高于对照组、肺结核组，差异有统计学意义（P＜0.05），但肺结核组与对照组比较，差异无统计学意义（P＞0.05）；肺结核合并胸膜钙化型、肥厚型血清CA125和SF水平均低于肺结核合并胸腔积液型，差异有统计学意义（P＜0.05）；血清CA125联合SF检测肺结核合并结核性胸膜炎的敏感度、特异度以及准确度均高于血清CA125、SF单纯检测，且CA125检测高于SF，差异有统计学意义（P＜0.05）。结论 血清 CA125和铁蛋白检测可作为肺结核合并结核性胸膜炎诊断和判断病情的重要指标。
Abstract:
Objective To study the clinical value of serum carbohydrate antigen 125 (CA125) and serum ferritin (SF) in patients with pulmonary tuberculosis complicated with tuberculous pleurisy.Methods 126 patients with pulmonary tuberculosis treated in our hospital from April 2020 to May 2021 were selected as the research subjects. According to whether pulmonary parenchymal lesions involved the pleura, 34 cases were divided into pulmonary tuberculosis group and 92 cases in the combined group (pulmonary tuberculosis combined with tuberculous pleurisy). Another 30 healthy subjects were selected as the control group. The serum levels of CA125 and SF, the levels of CA125 and SF in patients with different types of tuberculosis complicated with tuberculous pleurisy, and the sensitivity, specificity and accuracy of CA125, SF and CA125 combined with SF in the detection of tuberculosis complicated with tuberculous pleurisy were compared.Results The serum CA125 and SF in the combined group were higher than those in the control group and the pulmonary tuberculosis group, and the difference was statistically significant (P<0.05); however, there was no significant difference between the pulmonary tuberculosis group and the control group (P>0.05). The serum CA125 and SF levels of pulmonary tuberculosis with pleural calcification and hypertrophic type were lower than those of pulmonary tuberculosis with pleural effusion type, and the difference was statistically significant (P<0.05). The sensitivity, specificity and accuracy of serum CA125 combined with SF in the detection of pulmonary tuberculosis complicated with tuberculous pleurisy were higher than those of serum CA125 and SF, and the detection of CA125 was higher than that of SF, the difference was statistically significant (P<0.05).Conclusion The detection of serum CA125 and ferritin can be used as an important indicator for the diagnosis and judgment of tuberculosis complicated with tuberculous pleurisy.

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更新日期/Last Update: 1900-01-01