[1]徐茂林,高 斌.DWI和DCE-MRI鉴别诊断乳腺良恶性病变的价值[J].医学信息,2021,34(05):96-99.[doi:10.3969/j.issn.1006-1959.2021.05.027]
　XU Mao-lin,GAO Bin.The Value of DWI and DCE-MRI in Differential Diagnosis of Benign and Malignant Breast Lesions[J].Medical Information,2021,34(05):96-99.[doi:10.3969/j.issn.1006-1959.2021.05.027]
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DWI和DCE-MRI鉴别诊断乳腺良恶性病变的价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年05期
页码:
96-99
栏目:
论著
出版日期:
2021-03-01

文章信息/Info

Title:
The Value of DWI and DCE-MRI in Differential Diagnosis of Benign and Malignant Breast Lesions
文章编号:
1006-1959（2021）05-0096-04
作者:
徐茂林; 高 斌
（安徽医科大学第三附属医院影像中心，安徽 合肥 230000）
Author(s):
XU Mao-lin; GAO Bin
(Imaging Center,the Third Affiliated Hospital of Anhui Medical University,Hefei 230000,Anhui,China)
关键词:
乳腺肿瘤; 动态增强磁共振成像; 扩散加权成像
Keywords:
Breast tumor; Dynamic contrastenhanced magnetic resonance imaging; Diffusion weighted imaging
分类号:
R473.7
DOI:
10.3969/j.issn.1006-1959.2021.05.027
文献标志码:
A
摘要:
目的 探讨DWI和DCE-MRI鉴别诊断乳腺良恶性病变的价值。方法 回顾性分析2017年6月~2019年12月我院影像科病理证实的40例乳腺癌及35例乳腺良性病变的MRI影像资料，分析两组早期强化率、早期强化比值、信号增强比、峰值强化率、时间-信号强度曲线（TIC）类型、两侧乳腺血管差值及表观扩散系数（ADC值），并计算其诊断病变的敏感性及特异性。结果 两组峰值强化率比较，差异无统计学意义（P＞0.05），乳腺癌组早期强化率、早期强化比值、信号增强比大于乳腺良性病变组，ADC值小于乳腺良性病变组，差异均有统计学意义（P＜0.05）；乳腺癌组TIC类型I型1个、II型12个、III型27个，乳腺良性病变组TIC类型I型13个、II型20个、III型2个，两组比较，差异有统计学意义（P＜0.05）；乳腺癌组两侧乳腺血管差值0级6个、1级21个、2级13个，乳腺良性病变组两侧乳腺血管差值0级24个、1级10个、2级1个，两组比较，差异有统计学意义（P＜0.05）；ADC、早期强化率、早期强化比值、信号增强比及两侧乳腺血管差值ROC曲线下面积分别为0.947、0.666、0.785、0.933、0.804，敏感度为88.60%、90.00%、72.50%、82.50%、85.00%，特异度为95.00%、45.70%、80.00%、97.10%、68.60%。结论 DWI和DCE-MRI能够提高诊断医生对乳腺良恶性病变的鉴别能力，在病变诊断中ADC值及信号增强比具有较高的敏感性、特异性。
Abstract:
Objective To explore the value of DWI and DCE-MRI in the differential diagnosis of benign and malignant breast lesions.Methods Retrospectively analyzed the MRI imaging data of 40 cases of breast cancer and 35 cases of benign breast lesions confirmed by the imaging department of our hospital from June 2017 to December 2019, and analyzed the early enhancement rate, early enhancement ratio, signal enhancement ratio,peak enhancement rate, time-signal intensity curve (TIC) type, difference between breast vessels on both sides and apparent diffusion coefficient (ADC value), and calculate its sensitivity and specificity for diagnosing lesions.Results There was no statistically significant difference in the peak enhancement rate between the two groups (P>0.05).The early enhancement rate, early enhancement ratio and signal enhancement ratio of the breast cancer group were greater than those of the benign breast lesions group, and the ADC value was lower than that of the benign breast lesions group, the differences were statistically significant (P＜0.05);In the breast cancer group, 1 TIC type I, 12 type II, 27 type III, 13 TIC type I, 20 type II, and 2 type III in the benign breast lesion group,the difference between the two groups was statistically significant(P＜0.05);In the breast cancer group, there were 6 breast blood vessels at grade 0, 21 at grade 1, and 13 at grade 2.In the benign breast disease group, the difference between the breast vessels on both sides of the breast was 24 at grade 0, 10 at grade 1, and 1 at grade 2,the difference between the two groups was statistically significant (P＜0.05);ADC,early enhancement rate, early enhancement ratio, signal enhancement ratio, and the area under the ROC curve of the breast vessel difference on both sides are 0.947, 0.666, 0.785, 0.933, 0.804, respectively, and the sensitivity is 88.60%, 90.00%, 72.50%, 82.50% , 85.00%, the specificity is 95.00%, 45.70%, 80.00%, 97.10%, 68.60%.Conclusion DWI and DCE-MRI can improve the diagnostic ability of doctors to distinguish benign and malignant breast lesions, and ADC value and signal enhancement ratio have higher sensitivity and specificity in lesion diagnosis.

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更新日期/Last Update: 1900-01-01