[1]司书晗,解雪云,俞 倩,等.非编码RNA与缺血性脑卒中研究进展[J].医学信息,2024,37(02):168-171,181.[doi:10.3969/j.issn.1006-1959.2024.02.036]
 SI Shu-han,XIE Xue-yun,YU Qian,et al.Research Progress of Non-coding RNA and Ischemic Stroke[J].Journal of Medical Information,2024,37(02):168-171,181.[doi:10.3969/j.issn.1006-1959.2024.02.036]
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非编码RNA与缺血性脑卒中研究进展()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年02期
页码:
168-171,181
栏目:
综述
出版日期:
2024-01-15

文章信息/Info

Title:
Research Progress of Non-coding RNA and Ischemic Stroke
文章编号:
1006-1959(2024)02-0168-05
作者:
司书晗解雪云俞 倩
(上海中医药大学针灸推拿学院,上海 201203)
Author(s):
SI Shu-hanXIE Xue-yunYU Qianet al.
(College of Acupuncture and Tuina,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
关键词:
缺血性脑卒中非编码RNA微小RNA长链非编码RNA环状RNA竞争性内源性RNA
Keywords:
Ischemic strokeNon-coding RNAsMicro miRNALong non-coding RNACircular RNACompetitive endogenous RNA
分类号:
R743.3
DOI:
10.3969/j.issn.1006-1959.2024.02.036
文献标志码:
A
摘要:
脑卒中是由多种因素引起的一种急性脑循环障碍疾病,其中以缺血性脑卒中最常见。非编码RNA(ncRNAs)是一类不具有蛋白编码功能的RNA,在缺血性脑卒中的发生发展中具有重要的调控作用。近年来ncRNAs成为研究的热点,已有不少研究证实与缺血性脑卒中的病理生理的密切相关。本文主要从微小miRNA(miRNA)、长链非编码RNA(lncRNA)、环状RNA(circRNA)及竞争性内源RNA(ceRNA)调控网络研究进行综述,为缺血性脑卒中的防治提供新的思路。
Abstract:
Stroke is an acute cerebral circulatory disorder caused by many factors, among which ischemic stroke is the most common. Non-coding RNAs (ncRNAs) are a class of RNAs that do not have protein-coding functions and play an important regulatory role in the occurrence and development of ischemic stroke. In recent years, ncRNAs have become a research hotspot, and many studies have confirmed that they are closely related to the pathophysiology of ischemic stroke. This article mainly reviews the research of micro miRNA (miRNA), long non-coding RNA (lncRNA), circular RNA (circRNA) and competitive endogenous RNA (ceRNA) regulatory network, and provides new ideas for the prevention and treatment of ischemic stroke.

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更新日期/Last Update: 1900-01-01