[1]简余清.缩宫素结合卡前列素氨丁三醇在高危妊娠分娩者产后出血治疗中的作用[J].医学信息,2024,37(22):78-81.[doi:10.3969/j.issn.1006-1959.2024.22.019]
　JIAN Yuqing.Effrect of Oxytocin Combined with Carboprost Tromethamine in the Treatment of Postpartum Hemorrhage in High-risk Pregnant Women[J].Journal of Medical Information,2024,37(22):78-81.[doi:10.3969/j.issn.1006-1959.2024.22.019]
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缩宫素结合卡前列素氨丁三醇在高危妊娠分娩者产后出血治疗中的作用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年22期
页码:
78-81
栏目:
论著
出版日期:
2024-11-15

文章信息/Info

Title:
Effrect of Oxytocin Combined with Carboprost Tromethamine in the Treatment of Postpartum Hemorrhage in High-risk Pregnant Women
文章编号:
1006-1959（2024）22-0078-04
作者:
简余清
分宜县人民医院妇产科，江西 分宜 336600
Author(s):
JIAN Yuqing
Department of Obstetrics and Gynecology,Fenyi County People’s Hospital,Fenyi 336600,Jiangxi,China
关键词:
高危妊娠; 产后出血; 卡前列素氨丁三醇; 缩宫素
Keywords:
High-risk pregnancy; Postpartum hemorrhage; Carboprost tromethamine; Oxytocin
分类号:
R714.46
DOI:
10.3969/j.issn.1006-1959.2024.22.019
摘要:
目的 分析缩宫素结合卡前列素氨丁三醇在高危妊娠分娩者产后出血治疗中的作用。方法 选取2021年1月-2023年12月我院接收的40例高危妊娠产后出血产妇作为研究对象，按照随机数字表法分为对照组和研究组，每组20例。对照组给予缩宫素治疗，研究组在对照组基础上联合卡前列素氨丁三醇治疗。比较两组临床疗效、出血情况[红细胞比容（HCT）、血红蛋白（Hb）]、凝血功能[血浆纤维蛋白原（FIB）、活化部分凝血活酶时间（APTT）、D-二聚体（D-D）]及氧化应激指标水平[超氧化物歧化酶（SOD）、丙二醛（MDA）、过氧化氢酶（CAT）]。结果 研究组治疗总有效率（95.00%）高于对照组（70.00%）（P＜0.05）；研究组治疗后Hb、HCT水平高于对照组（P＜0.05）；研究组APTT、D-D水平低于对照组，FIB水平高于对照组（P＜0.05）；研究组MDA水平低于对照组，CAT、SOD水平高于对照组（P＜0.05）。结论 缩宫素结合卡前列素氨丁三醇可改善高危妊娠分娩者产后的凝血功能和氧化应激反应，防止产后出血，效果确切，值得临床应用。
Abstract:
Objective To analyze the effect of oxytocin combined with carboprost tromethamine in the treatment of postpartum hemorrhage in high-risk pregnant women.Methods A total of 40 high-risk pregnant women with postpartum hemorrhage received in our hospital from January 2021 to December 2023 were selected as the research objects. According to the random number table method, they were divided into control group and study group, with 20 high-risk pregnant women in each group. The control group was treated with oxytocin, and the study group was treated with carboprost tromethamine on the basis of the control group. The clinical efficacy, bleeding [hematocrit (HCT), hemoglobin (Hb)], coagulation function [plasma fibrinogen (FIB), activated partial thromboplastin time (APTT), D-dimer (D-D)] and oxidative stress index levels [superoxide dismutase (SOD), malondialdehyde (MDA), catalase (CAT)] were compared between the two groups.Results The total effective rate of treatment in the study group (95.00%) was higher than that in the control group (70.00%) (P<0.05). The levels of Hb and HCT in the study group were higher than those in the control group (P<0.05). The APTT and D-D levels in the study group were lower than those in the control group, and the FIB level was higher than that in the control group (P<0.05). The MDA level in the study group was lower than that in the control group, and the CAT and SOD levels were higher than those in the control group (P<0.05).Conclusion Oxytocin combined with carboprost tromethamine can improve the postpartum coagulation function and oxidative stress reaction in high-risk pregnancy women, and prevent postpartum hemorrhage. The effect is definite and worthy of clinical application.

参考文献/References:

[1]谢晖,田辛梓.卡前列素氨丁三醇联合缩宫素治疗高危妊娠阴道分娩产后出血的临床疗效及其对血流动力学的影响研究[J].贵州医药,2022,46(9):1394-1395.[2]黄华,杨建碧.前列腺素类药物联合缩宫素预防高危妊娠剖宫产产后出血效果观察[J].蚌埠医学院学报,2019,44(5):597-599,603.[3]刘伟,贾倩,李会霞,等.卡前列素氨丁三醇防治高危妊娠产后出血的临床疗效及对孕产妇分娩方式、母婴结局的影响[J].解放军预防医学杂志,2019,37(6):114-115.[4]薛文先.卡前列素氨丁三醇与米索前列醇分别联合缩宫素在高危剖宫产产妇产后出血防治中的应用[J].中国药物与临床,2020,20(18):3105-3106.[5]刘彬彬.卡前列素氨丁三醇联合缩宫素对剖宫产产妇产后出血的疗效及对凝血功能、氧化应激指标的影响[J].中国妇幼保健,2020,35(7):1228-1231.[6]刘海燕,段茉莉.缩宫素联合卡前列素氨丁三醇治疗产后出血的效果及对产妇凝血因子水平的影响[J].中国妇幼保健,2019,34(24):5594-5596.[7]沙小龙,王倩.卡前列素氨丁三醇联合改良式B-Lynch缝扎术及限制性补液疗法对剖宫产术中产后出血的综合治疗研究[J].河北医学,2018,24(9):1482-1486. [8]杨青青,田阗,郑泽玉,等.缩宫素联合卡前列素氨丁三醇对产后出血患者凝血功能及血流动力学的影响[J].现代生物医学进展,2018,18(14):2742-2745,2767.[9]张雁平.卡前列素氨丁三醇联合缩宫素在剖宫产宫缩乏力性产后出血防治中的应用[J].中国药物与临床,2021,21(10):1736-1738.[10]郑秋午,洪平,胡胜梅,等.注射益母草注射液、卡前列素氨丁三醇对剖宫产产妇产后出血的预防效果以及不良反应观察[J].临床和实验医学杂志,2023,22(4):403-406.[11]张学玲,刘军.卡前列素氨丁三醇注射液联合子宫动脉下行支结扎治疗宫缩乏力性产后出血疗效评价[J].中国药业,2018,27(15):58-60.[12]杨艳芬,田立霞,万秋爽.麦角新碱、欣母沛和缩宫素预防和治疗阴道分娩宫缩乏力性产后出血疗效及安全性[J].中国计划生育学杂志,2019,27(10):1343-1347.[13]周海红,金红梅.卡前列甲酯栓联合卡前列素氨丁三醇预防和治疗子宫收缩乏力性产后出血的临床效果与安全性[J].中国医药,2021,16(5):741-744.[14]袁海英,高娟,夏亚芳.不同剂量缩宫素联合卡前列素氨丁三醇对高危产妇剖宫产术后出血及血流动力学的影响[J].中国医药,2018,13(10):1567-1571.[15]陈琳,陈鹤鸣,杨栋.卡前列素氨丁三醇对剖宫产术患者血浆钙、D-二聚体水平的影响及对产后出血的防治效果[J].临床和实验医学杂志,2019,18(22):2428-2431.[16]张婧,张忠明.剖宫产术后应用宫体注射卡前列素氨丁三醇对产后出血预防效果及凝血功能的影响[J].河北医科大学学报,2019,40(1):102-105.[17]季晓菲,卢灿娣,罗丽莉,等.卡前列素氨丁三醇联合低位B-Lynch缝合术治疗难治性前置胎盘性产后出血的临床观察[J].中国性科学,2019,28(11):76-78.[18]姜陵,韦昕芳,王瑞芳.卡前列素氨丁三醇联合卡贝缩宫素对前置胎盘剖宫产产妇相关指标的影响[J].西北药学杂志,2019,34(2):253-256.

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更新日期/Last Update: 1900-01-01