[1]周雯雯.法莫替丁与奥美拉唑钠治疗儿童消化性溃疡的效价[J].医学信息,2020,33(17):146-147.[doi:10.3969/j.issn.1006-1959.2020.17.042]
　ZHOU Wen-wen.The Potency of Famotidine and Omeprazole Sodium in the Treatment of Peptic Ulcer in Children[J].Medical Information,2020,33(17):146-147.[doi:10.3969/j.issn.1006-1959.2020.17.042]
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法莫替丁与奥美拉唑钠治疗儿童消化性溃疡的效价()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年17期
页码:
146-147
栏目:
药物与临床
出版日期:
2020-09-01

文章信息/Info

Title:
The Potency of Famotidine and Omeprazole Sodium in the Treatment of Peptic Ulcer in Children
文章编号:
1006-1959（2020）17-0146-02
作者:
周雯雯
（佳木斯市中心医院儿科，黑龙江 佳木斯 154002）
Author(s):
ZHOU Wen-wen
(Department of Pediatrics,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
关键词:
法莫替丁; 奥美拉唑钠; 消化性溃疡
Keywords:
Famotidine; Omeprazole sodium; Peptic ulcer
分类号:
R725.7
DOI:
10.3969/j.issn.1006-1959.2020.17.042
文献标志码:
A
摘要:
目的 观察法莫替丁与奥美拉唑钠治疗儿童消化性溃疡的效价。方法 选取2018年12月~2019年10月在我院诊治的84例消化性溃疡儿童为研究对象，采用随机数字表法分为对照组和观察组，各42例。对照组采用奥美拉唑钠治疗，观察组采用法莫替丁治疗，比较两组临床治疗总有效率、治疗费用、成本-效益比及临床不良反应发生情况。结果 观察组治疗总有效率为95.23%，与对照组的92.85%比较，差异无统计学意义（P＞0.05）；观察组平均治疗费用低于对照组，成本-效益比均高于对照组，差异有统计学意义（P＜0.05）；观察组不良反应发生率为7.14%，与对照组的11.90%比较，差异无统计学意义（P＞0.05）。结论 法莫替丁与奥美拉唑钠治疗儿童消化性溃疡疗效相似，均具有较高的有效率，但是法莫替丁成本-效益高，相对安全，适合临床治疗儿童消化性溃疡的应用。
Abstract:
Objective To observe the potency of famotidine and omeprazole sodium in the treatment of peptic ulcer in children.Methods A total of 84 children with peptic ulcer who were diagnosed and treated in our hospital from December 2018 to October 2019 were selected as the research objects. They were divided into the control group and the observation group by random number table, with 42 cases in each group. The control group was treated with omeprazole sodium, and the observation group was treated with famotidine. The total effective rate, treatment cost, cost-benefit ratio and clinical adverse reactions were compared between the two groups. Results The total effective rate of treatment in the observation group was 95.23%.Compared with 92.85% in the control group,there was no statistically significant difference (P>0.05);The average treatment cost of the observation group was lower than that of the control group, and the cost-benefit ratio was higher than that of the control group,the difference was statistically significant (P<0.05); the adverse reaction rate of the observation group was 7.14%, which was a difference compared with 11.90% of the control group,the difference was not statistically significant (P>0.05).Conclusion Famotidine and omeprazole sodium have similar curative effects in the treatment of peptic ulcer in children, and both have higher effective rates.However,famotidine is cost-effective, relatively safe,and suitable for clinical treatment of peptic ulcer in children.

参考文献/References:

[1]邱慧明,熊斌.小儿消化性溃疡幽门螺杆菌感染的相关危险因素分析[J].浙江中西医结合杂志,2017,19(1):68-71.[2]张琪.近5年消化性溃疡中西医结合防治进展述评[J].实用中西医结合临床,2016,16(3):90-92.[3]刘辽,杨代喜,蒋丹,等.康复新液联合泮托拉唑治疗消化性溃疡疗效及安全性的系统评价[J].中成药,2014,36(3):491-497.[4]龚雪萍.奥美拉唑联合奥曲肽治疗消化性溃疡合并上消化道出血的临床疗效分析[J].当代医学,2015,(21):113-114.[5]黄绍精.奥美拉唑与泮托拉唑治疗消化性溃疡出血的临床疗效对比[J].临床合理用药杂志,2015,19(12):52-53.[6]杨冰.泮托拉唑与法莫替丁治疗消化性溃疡104例疗效比较[J].当代医学,2015,5(19):139-140.

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更新日期/Last Update: 1900-01-01