[1]王争艳,宋发荣.中药月经周期疗法治疗PCOS不孕症的效果[J].医学信息,2020,33(20):153-155.[doi:10.3969/j.issn.1006-1959.2020.20.048]
 WANG Zheng-yan,SONG Fa-rong.The Effect of Chinese Medicine Menstrual Cycle Therapy on PCOS Infertility[J].Medical Information,2020,33(20):153-155.[doi:10.3969/j.issn.1006-1959.2020.20.048]
点击复制

中药月经周期疗法治疗PCOS不孕症的效果()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年20期
页码:
153-155
栏目:
中医中药
出版日期:
2020-10-15

文章信息/Info

Title:
The Effect of Chinese Medicine Menstrual Cycle Therapy on PCOS Infertility
文章编号:
1006-1959(2020)20-0153-03
作者:
王争艳宋发荣
(高安市中医院妇产科1,内分泌科2,江西 高安 330800)
Author(s):
WANG Zheng-yanSONG Fa-rong
(Department of Obstetrics and Gynecology1,Department of Endocrinology2,Gaoan Traditional Chinese Medicine Hospital, Gaoan 330800,Jiangxi,China)
关键词:
多囊卵巢综合征不孕症克罗米芬中药周期疗法
Keywords:
Polycystic ovary syndromeInfertilityClomipheneCycle therapy with traditional Chinese medicine
分类号:
R711.6
DOI:
10.3969/j.issn.1006-1959.2020.20.048
文献标志码:
A
摘要:
目的 观察中药月经周期疗法联合克罗米芬和戊酸雌二醇治疗多囊卵巢综合征(PCOS)不孕症患者的临床效果。方法 选取2015年10月~2018年10月我科收治的96例PCOS不孕症患者作为研究对象,按照随机数字表法分为观察组和对照组,每组48例。对照组予克罗米芬和戊酸雌二醇口服治疗,观察组在此基础上给予中药月经周期疗法,比较两组血清促卵泡激素(FSH))、黄体生成素(LH)、总睾酮(T)水平、体重指数(BMI)、排卵率及妊娠率。结果 治疗后,两组血清FSH、LH、T水平及BMI均下降,且观察组低于对照组,差异有统计学意义(P<0.05);观察组总周期排卵率、总妊娠率均高于对照组(80.56% vs 63.41%)、(70.83% vs 37.50%),差异有统计学意义(P<0.05)。结论 克罗米芬和戊酸雌二醇口服治疗基础上采用中药月经周期疗法可调节患者的内分泌功能,改善其BMI,提高其排卵率和妊娠率。
Abstract:
Objective To observe the clinical effect of Chinese medicine menstrual cycle therapy combined with clomiphene and estradiol valerate in the treatment of infertility patients with polycystic ovary syndrome (PCOS).Methods A total of 96 patients with PCOS infertility who were admitted to our department from October 2015 to October 2018 were selected as the research objects. According to the random number table method, they were divided into observation group and control group, with 48 cases in each group. The control group was given oral clomiphene and estradiol valerate, and the observation group was given menstrual cycle therapy with traditional Chinese medicine on this basis. Serum follicle-stimulating hormone (FSH), luteinizing hormone (LH) and total testosterone (T) levels were compared between the two groups,body mass index (BMI), ovulation rate and pregnancy rate.Results After treatment, the two groups of serum FSH, LH, T levels and BMI decreased, and the observation group was lower than the control group, the difference was statistically significant (P<0.05); the observation group’s total cycle ovulation rate and total pregnancy rate were higher than the control group(80.56% vs 63.41%), (70.83% vs 37.50%), the difference was statistically significant(P<0.05).Conclusion On the basis of oral treatment of clomiphene and estradiol valerate, the use of traditional Chinese medicine menstrual cycle therapy could regulate the endocrine function of patients, improve their BMI, and increase their ovulation rate and pregnancy rate.

参考文献/References:

[1]李春梅,李娟.二甲双胍联合来曲唑治疗多囊卵巢综合征对患者子宫内膜容受性及性激素水平影响[J].中国计划生育学杂志,2020,28(6):843-846. [2]王婷婷,付翰林,陈立章,等.中国多囊卵巢综合征患者妊娠并发症发生率的Meta分析[J].中南大学学报(医学版),2017,42(11):1300-1310. [3]张小文.补肾活血汤加减联合枸橼酸氯米芬胶囊治疗肾虚血瘀型多囊卵巢综合征所致不孕症临床研究[J].新中医,2020,52(13):46-48. [4]豆竹丽,阮祥燕,鞠蕊,等.综合干预后多囊卵巢综合征不孕患者应用来曲唑促排卵的临床效果[J].首都医科大学学报,2020(4):525-529. [5]赵文晓,连方.连方治疗多囊卵巢综合征性不孕症经验[J].湖南中医杂志,2013,29(11):23-24. [6]黄伟燕.二甲双胍联合氯米芬对多囊卵巢综合征并不孕症患者内皮功能、内分泌指标和临床结局的影响[J].中国基层医药,2019(21):2643-2648. [7]唐玉珠,苏椿淋,王经纬,等.基于人体成分测定进行互联网线上生活方式干预在多囊卵巢综合征患者治疗中作用的多中心前瞻性研究[J].中华生殖与避孕杂志,2019(3):177-184. [8]刘湾湾,唐玲丽,李东海,等.二甲双胍对中心性肥胖和非中心性肥胖多囊卵巢综合征患者生殖内分泌及糖脂代谢的影响[J].中华生殖与避孕杂志,2019(1):57-60. [9]杨志琴,闫冰.桂枝茯苓丸合当归芍药汤联合二甲双胍片对肥胖型多囊卵巢综合征卵巢体积及卵泡数目的影响[J].国际中医中药杂志,2018,40(5):398-401. [10]丁祥云,于清梅,张文芳,等.胰岛素样生长因子Ⅱ在84例多囊卵巢综合征患者颗粒细胞中的表达和促排卵结局的相关性[J].山东大学学报(医学版),2020. [11]刘文娟,孙小红,刘晓娟,等.炔雌醇环丙孕酮片联合二甲双胍对多囊卵巢综合征患者血清DHEA、AMH及SHBG水平的影响[J].中国现代医学杂志,2020,30(12):109-113. [12]李砚,姚念玲,王运萍,等.来曲唑与克罗米芬治疗多囊卵巢综合征的疗效及对促排卵的效果比较[J].海南医学,2019,30(15):1965-1968. [13]赵红利,孟宜波,张静.炔雌醇环丙孕酮联合二甲双胍治疗非肥胖型多囊卵巢综合征的疗效及安全性[J].临床药物治疗杂志,2020,18(6):49-53. [14]吴苏豫,周艳红,赵建林,等.二甲双胍联合复方醋酸环丙孕酮治疗多囊卵巢综合征的临床疗效和安全性分析[J].四川解剖学杂志,2020,28(2):39-40. [15]王宪,刘桂荣.基于数据挖掘对中医周期疗法治疗多囊卵巢综合征用药规律及作用机制研究[J].中国中医基础医学杂志,2018,24(5):688-690,712. [16]张媛,王宇吉,刘冰艺,等.五积散联合克罗米芬治疗痰湿型多囊卵巢综合征不孕症临床研究[J].南京中医药大学学报,2020(4):444-448.

相似文献/References:

[1]黄震洲,张龙梅,荣宝山.黄海波教授三紫汤诊治子宫性不孕经验浅谈[J].医学信息,2018,31(10):143.[doi:10.3969/j.issn.1006-1959.2018.10.048]
 HUANG Zhen-zhou,ZHANG Long-mei,RONG Bao-shan.Professor Huang Haibo's Experience in Treating Uterus Infertility with Sanzi Decoction[J].Medical Information,2018,31(20):143.[doi:10.3969/j.issn.1006-1959.2018.10.048]
[2]袁 奔,潘 伟,罗淑红,等.体重指数对多囊卵巢综合征患者 人工授精妊娠结局影响[J].医学信息,2018,31(12):99.[doi:10.3969/j.issn.1006-1959.2018.12.030]
 YUAN Ben,PAN Wei,LUO Shu-hong,et al.Effects of Body Mass Index on the Outcome of Artificial Insemination in Patients with Polycystic Ovary Syndrome[J].Medical Information,2018,31(20):99.[doi:10.3969/j.issn.1006-1959.2018.12.030]
[3]罗红财,沈 颖,黄莉珊,等.基于温肾助阳、暖宫温胞改善卵巢功能异常的机制分析[J].医学信息,2022,35(11):172.[doi:10.3969/j.issn.1006-1959.2022.11.046]
 LUO Hong-cai,SHEN Ying,HUANG Li-shan,et al.The Mechanism Analysis of Improve Symptoms Related to Ovarian Dysfunction Based on Warming Kidney and Helping Yang,Warming Baogong[J].Medical Information,2022,35(20):172.[doi:10.3969/j.issn.1006-1959.2022.11.046]
[4]曾利文,陈 静,张 晔,等.多囊卵巢综合征患者的糖代谢特点分析[J].医学信息,2019,32(02):103.[doi:10.3969/j.issn.1006-1959.2019.02.029]
 ZENG Li-wen,CHEN Jing,ZHANG Ye,et al.Analysis of Characteristics of Glucose Metabolism in Patients with Polycystic Ovarian Syndrome[J].Medical Information,2019,32(20):103.[doi:10.3969/j.issn.1006-1959.2019.02.029]
[5]李德君,李慧君.来曲唑联合苍附导痰汤治疗多囊卵巢综合征不孕症患者的 临床观察[J].医学信息,2018,31(17):137.[doi:10.3969/j.issn.1006-1959.2018.17.043]
 LI De-jun,LI Hui-jun.Clinical Observation of Letrozole Combined with Cangfu Daotan Decoction in the Treatment of Infertility Patients with Polycystic Ovary Syndrome[J].Medical Information,2018,31(20):137.[doi:10.3969/j.issn.1006-1959.2018.17.043]
[6]陈 丽,郝丽娟.多囊卵巢综合征患者腹型肥胖、高雄、胰岛素抵抗及脂代谢的相关性分析[J].医学信息,2022,35(12):113.[doi:10.3969/j.issn.1006-1959.2022.12.027]
 CHEN Li,HAO Li-juan.Correlation of Abdominal Obesity, Hyperandrogenism, Insulin Resistance and Lipid Metabolism in Patients with Polycystic Ovary Syndrome[J].Medical Information,2022,35(20):113.[doi:10.3969/j.issn.1006-1959.2022.12.027]
[7]左俊芳,刘沙沙,崔洪艳.妊娠期糖尿病高危因素及预防措施研究[J].医学信息,2022,35(17):177.[doi:10.3969/j.issn.1006-1959.2022.17.048]
 ZUO Jun-fang,LIU Sha-sha,CUI Hong-yan.Study on High Risk Factors and Preventive Measures of Gestational Diabetes Mellitus[J].Medical Information,2022,35(20):177.[doi:10.3969/j.issn.1006-1959.2022.17.048]
[8]杜 娟.亮丙瑞林治疗子宫内膜异位症伴不孕的应用[J].医学信息,2020,33(13):43.[doi:10.3969/j.issn.1006-1959.2020.13.012]
 DU Juan.Application of Leuprolide in the Treatment of Endometriosis with Infertility[J].Medical Information,2020,33(20):43.[doi:10.3969/j.issn.1006-1959.2020.13.012]
[9]朱 艳,周 琴,安 洁,等.脂联素基因单核苷酸多态性与多囊卵巢综合征伴胰岛素抵抗的关系研究[J].医学信息,2020,33(22):87.[doi:10.3969/j.issn.1006-1959.2020.22.025]
 ZHU Yan,ZHOU Qin,AN Jie,et al.Study on the Relationship Between Adiponectin Gene Single Nucleotide Polymorphism and Polycystic Ovary Syndrome with Insulin Resistance[J].Medical Information,2020,33(20):87.[doi:10.3969/j.issn.1006-1959.2020.22.025]
[10]王海燕,毕雪玲,曹 晶,等.坤泰胶囊联合炔雌醇环丙孕酮片、二甲双胍治疗多囊卵巢综合征的效果及对性激素的影响[J].医学信息,2020,33(20):129.[doi:10.3969/j.issn.1006-1959.2020.20.039]
 WANG Hai-yan,BI Xue-ling,CAO Jing,et al.The Effect of Kuntai Capsule Combined with Ethinyl Estradiol and Cyproterone Tablets and Metformin in the Treatment of Polycystic Ovary Syndrome and Its Influence on Sex Hormones[J].Medical Information,2020,33(20):129.[doi:10.3969/j.issn.1006-1959.2020.20.039]
[11]谢 丹.不同促排卵方案治疗多囊卵巢综合征不孕症的效果[J].医学信息,2020,33(18):141.[doi:10.3969/j.issn.1006-1959.2020.18.046]
 XIE Dan.The Effect of Different Ovulation Induction Programs on the Infertility of Polycystic Ovary Syndrome[J].Medical Information,2020,33(20):141.[doi:10.3969/j.issn.1006-1959.2020.18.046]

更新日期/Last Update: 1900-01-01