[1]何曦萌,王 超,孙军刚.针灸治疗高尿酸血症临床疗效及其机制[J].医学信息,2021,34(05):43-45.[doi:10.3969/j.issn.1006-1959.2021.05.013]
 HE Xi-meng,WANG Chao,SUN Jun-gang.Clinical Effect and Mechanism of Acupuncture and Moxibustion on Hyperuricemia[J].Medical Information,2021,34(05):43-45.[doi:10.3969/j.issn.1006-1959.2021.05.013]
点击复制

针灸治疗高尿酸血症临床疗效及其机制()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年05期
页码:
43-45
栏目:
综述
出版日期:
2021-03-01

文章信息/Info

Title:
Clinical Effect and Mechanism of Acupuncture and Moxibustion on Hyperuricemia
文章编号:
1006-1959(2021)05-0043-03
作者:
何曦萌王 超孙军刚
(1.成都中医药大学,四川 成都 610000; 2.四川省中西医结合医院亚健康中心,四川 成都 610000)
Author(s):
HE Xi-mengWANG ChaoSUN Jun-gang
(1.Chengdu University of TCM,Chengdu 610000,Sichuan,China; 2.Sub-Health Center,Sichuan Integrated Traditional Chinese and Western Medicine Hospital,Chengdu 610000,Sichuan,China)
关键词:
高尿酸血症针灸代谢综合征
Keywords:
Hyperuricemia Acupuncture Metabolic syndrome
分类号:
R246.1
DOI:
10.3969/j.issn.1006-1959.2021.05.013
文献标志码:
A
摘要:
近年来,高尿酸血症发病率逐年升高,成为仅次于糖尿病的第2大代谢性疾病,是痛风、心脑血管疾病、肾脏疾病及代谢综合征等疾病的独立危险因素。针灸作为传统医学重要疗法之一,在降尿酸以及缓解尿酸盐引起的炎性反应中取得了良好疗效。近年研究发现针灸治疗高尿酸血症作用机制可能与调节尿酸代谢关键酶的活性和缓解微炎症状态相关。本文综述近年来高尿酸血症针灸治疗的相关文献,以期为临床治疗策略以及相关机制研究提供参考。
Abstract:
In recent years, the incidence of hyperuricemia has been increasing year by year and has become the second largest metabolic disease after diabetes. It is an independent risk factor for diseases such as gout, cardiovascular and cerebrovascular diseases, kidney diseases and metabolic syndrome.Acupuncture, as one of the important therapies of traditional medicine, has achieved good effects in reducing uric acid and alleviating the inflammatory reaction caused by urate.Recent studies have found that the mechanism of acupuncture treatment of hyperuricemia may be related to regulating the activity of key enzymes in uric acid metabolism and relieving micro-inflammatory conditions.This article reviews the literature on acupuncture and moxibustion treatment of hyperuricemia in recent years, hoping to provide references for clinical treatment strategies and related mechanism research.

参考文献/References:

[1]高尿酸血症相关疾病诊疗多学科共识专家组.中国高尿酸血症相关疾病诊疗多学科专家共识[J].中华内科杂志,2017,56(3):235-249. [2]Li L,Zhang Y,Zeng C.Update on the epidemiology,genetics,and therapeutic options of hyperuricemia[J].American Journal of Translational Research,12(7):3167-3181. [3]Otani N,Ouchi M,Kudo H,et al.Recent approaches to gout drug discovery:an update[J].Expert Opinion on Drug Discovery,2020(1):1-12. [4]Lee SJ,Terkeltaub RA.New developments in clinically relevant mechanisms and treatment of hyperuricemia[J].Current Rheumatology Reports,2006,8(3):224-230. [5]Bock LW,Hyeon WS,Byung-Il M,et al.Acupuncture for gouty arthritis:a concise report of a systematic and meta-analysis approach[J].Rheumatology(Oxford),2013,52(7):1225-1232. [6]Sun J,Fan Y,Yang Z,et al.Efficacy and safety of fire-needle in the treatment of gouty arthritis:A protocol for systematic review and meta analysis[J].Medicine,2020,99(30):e21259. [7]Gustafsson D,Unwin R.The pathophysiology of hyperuricaemia and its possible relationship to cardiovascular disease,morbidity and mortality[J].BMC Nephrology,2013,14(1):164. [8]Fathallah-Shaykh SA,Cramer MT.Uric acid and the kidney[J].Pediatric Nephrology,2014, 29(6):999-1008. . [9]王先敏,马丽.高尿酸血症用药规律的计量学研究[J].中国实验方剂学杂志,2011,17(1):221-223. [10]田同良.朱良春治疗痹证"药对"经验探析[J].辽宁中医杂志,2007,34(11):1523-1524. [11]Sun BG,Meng J,Xiang T,et al.Acupuncture of the Five Shu Acupoints in spleen meridian to lower blood uric acid level[J].Ann Palliat Med,2014,3(1):22-27. [12]陆欣玲,李瑞玲,沈卫东.针刺治疗高尿酸血症的临床效果[J].中国医药导报,2017,14(25):102-105. [13]薄海艳,徐忠敏.针刺结合药饮防治高尿酸血症研究[J].上海医药,2015,36(2):43-45. [14]狄媛,段卫平,纪胜翔.电针联合刺络拔罐法治疗高尿酸血症临床观察[J].光明中医,2019,34(12):1875-1878. [15]Huang Y,Meng J,Sun B, et al.Acupuncture for serum uric acid in patients with asymptomatic hyperuricemia:A randomized,double-blind,placebo-controlled trial[J].International Journal of Cardiology,2017,232(1):227-232. [16]刘旭峰,陈虹屹,王菁,等.针刺"肾俞""太溪"穴对高尿酸血症大鼠尿酸的影响及其机制研究[J].针刺研究,2019,44(5):319-323+328. [17]何晓茜,唐雪青,刘佳男,等.穴位贴敷对高尿酸血症模型大鼠尿酸排泄的影响[J].中国中医急症,2020,29(6):1040-1044. [18]陈虹屹,刘旭峰,云素,等.针刺肝俞、太冲穴对高尿酸血症大鼠模型尿酸生成的影响及机制研究[J].针灸临床杂志,2019,35(3):56-60,89. [19]李彤.针灸化瘀通络法对痛风性关节炎及高尿酸血症影响的实验研究[D].成都中医药大学,2006. [20]程留慧,王道清,张保朋,等.无症状高尿酸血症患者及痛风患者四肢关节尿酸盐结晶的双源CT对比分析[J].中华风湿病学杂志,2015,19(10):686-689. [21]赵劲涛,黄胜华,连希艳,等.无症状高尿酸血症对微炎症状态的影响[J].临床内科杂志,2012;29(7):460-462. [22]蒋云,沈成兴,潘静薇,等.高尿酸血症诱导NLRP3炎症小体活化GSDMD对血管内皮细胞的影响[J].中国循证心血管医学杂志,2020,12(5):612-615. [23]张彩香,林章梅,梁艳玲,等.高尿酸血症患者血清白介素-6和转化生长因子-β1水平及应用非布司他治疗前后的变化[J].中国糖尿病杂志,2016,24(3):250-253. [24]陈圆玲,王佳佩,孙楠,等.儿童高尿酸血症血清IL-1β、IL-6水平及其临床意义[J].临床儿科杂志,2017,35(8):592-596. [25]陆燕云.针药结合对急性痛风性关节炎疗效及炎症因子IL-1β、IL-8影响的临床研究[D].广西中医药大学,2016. [26]卢翠娜,谢丽琴,李丽霞,等.火针对急性痛风性关节炎大鼠NALP3、IL-1β表达的影响[J].上海中医药杂志,2018,52(3):81-86. [27]龙天雷,黄腾蛟,高巧玲,等.通经利浊针法对急性痛风性关节炎大鼠模型影响的实验研究[J].世界中医药,2016,11(2):219-221. [28]高莉,付春爱,袁延鑫.电针对湿热蕴结型痛风性膝关节炎NLRP3炎性体的影响[J].世界中医药,2019,14(11):3045-3049,3053. [29]黄胜男,林志健,张冰,等.肠道菌群结构变化与高尿酸血症发生的关系[J].北京中医药大学学报,2015,38(7):452-456. [30]纪泽敏,牟菲,陈姝琴,等.基于倾向性评分匹配法筛选高尿酸血症的差异核心菌群[J].实用医学杂志,2020,36(2):233-238. [31]王茜,陈侃俊,余安胜.针灸治疗肝郁脾虚型肠易激综合征疗效及机制探讨[J].中国中西医结合消化杂志,2019,27(7):520-524. [32]谢文松,魏录翠,王金周,等.针刺联合中药治疗溃疡性结肠炎疗效及对相关指标的影响[J].上海针灸杂志,2019,38(4):378-383. [33]张博,熊壮,姜鑫.自拟扶正平溃汤联合针灸治疗慢性溃疡性结肠炎的疗效及对肠道菌群失调和Th17/Treg细胞免疫平衡的影响[J].现代中西医结合杂志,2018,27(11):1164-1167,1171. [34]陈斌,白羽,陈芮,等.艾灸对诱导性大鼠关节炎症及肠道菌群的影响[J].中国微生态学杂志,2019,31(6):632-637. [35]武欢,陈丽,梁凤霞.电针对胰岛素抵抗肥胖大鼠肠道菌群和肠道屏障的影响[J].时珍国医国药,2019,30(11):2808-2811.

相似文献/References:

[1]孙 秋,万 明,冯会芳,等.高尿酸血症生化血常规特征分析[J].医学信息,2018,31(06):153.[doi:10.3969/j.issn.1006-1959.2018.06.054]
 SUN Qiu,WAN Ming,FENG Hui-fang,et al.Analysis of Biochemical Blood Routine Characteristics of Hyperuricemia[J].Medical Information,2018,31(05):153.[doi:10.3969/j.issn.1006-1959.2018.06.054]
[2]金秀明.水族整脊疗法联合针灸治疗中风后遗症的效果观察[J].医学信息,2018,31(09):150.[doi:10.3969/j.issn.1006-1959.2018.09.048]
 JIN Xiu-ming.Clinical Observation on Effect of Aquatic Chiropractic Therapy Combined with Acupuncture in Treating Sequela of Apoplexy[J].Medical Information,2018,31(05):150.[doi:10.3969/j.issn.1006-1959.2018.09.048]
[3]刘 超.整脊疗法配合针灸疗法治疗神经根型颈椎病的疗效观察[J].医学信息,2018,31(11):142.[doi:10.3969/j.issn.1006-1959.2018.11.046]
 LIU Chao.Clinical Efficacy of Chiropractic Therapy Combined with Acupuncture and Moxibustion in the Treatment of Cervical Spondylotic Radicular[J].Medical Information,2018,31(05):142.[doi:10.3969/j.issn.1006-1959.2018.11.046]
[4]陈倩倩.针灸对围绝经期抑郁症单胺类神经递质影响的关联性研究[J].医学信息,2018,31(12):54.[doi:10.3969/j.issn.1006-1959.2018.12.017]
 CHEN Qian-qian.Association between Acupuncture and Moxibustion on Monoamine Neurotransmitter in Perimenopausal Depressive Disorder[J].Medical Information,2018,31(05):54.[doi:10.3969/j.issn.1006-1959.2018.12.017]
[5]崔 凯.针灸治疗周围性面瘫的临床疗效及其对面神经功能的影响[J].医学信息,2022,35(10):162.[doi:10.3969/j.issn.1006-1959.2022.10.041]
 CUI Kai.Clinical Effect of Acupuncture on Peripheral Facial Paralysis and its Effect on Facial Nerve Function[J].Medical Information,2022,35(05):162.[doi:10.3969/j.issn.1006-1959.2022.10.041]
[6]俞 瑞,吴建荣,杨晓萍,等.健康体检者中高尿酸人群血脂水平变化及 甘油三脂升高的相关因素分析[J].医学信息,2018,31(13):62.[doi:10.3969/j.issn.1006-1959.2018.13.018]
 YU Rui,WU Jian-rong,YANG Xiao-ping,et al.Analysis of Related Factors of Blood Lipid Levels and Elevated Triglycerides in Hyperuricemia Population in Healthy Subjects[J].Medical Information,2018,31(05):62.[doi:10.3969/j.issn.1006-1959.2018.13.018]
[7]张 铭,徐 蔷,肖 帆,等.芹菜籽提取物对高尿酸血症模型大鼠的血尿酸以及 抗氧化能力的影响[J].医学信息,2018,31(13):84.[doi:10.3969/j.issn.1006-1959.2018.13.024]
 ZHANG Ming,XU Qiang,XIAO Fan,et al.Effects of Celery Seed Extract on Serum Uric Acid and Antioxidant Capacity of Hyperuricemia Rats[J].Medical Information,2018,31(05):84.[doi:10.3969/j.issn.1006-1959.2018.13.024]
[8]高大红,王友刚.近十年针灸治疗原发性痛经的临床研究[J].医学信息,2018,31(14):39.[doi:10.3969/j.issn.1006-1959.2018.14.013]
 GAO Da-hong,WANG You-gang.Clinical Research on Acupuncture and Moxibustion in Treating Primary Dysmenorrhea in Recent Ten Years[J].Medical Information,2018,31(05):39.[doi:10.3969/j.issn.1006-1959.2018.14.013]
[9]杨晓鸿.针灸联合身痛逐淤汤加减对中风恢复期丘脑痛疼痛程度及血液流变学指标的影响[J].医学信息,2022,35(11):177.[doi:10.3969/j.issn.1006-1959.2022.11.047]
 YANG Xiao-hong.Effect of Acupuncture Combined with Shentong Zhuyu Decoction on the Degree of Thalamus Pain and Hemorheology Index in Stroke Recovery Period[J].Medical Information,2022,35(05):177.[doi:10.3969/j.issn.1006-1959.2022.11.047]
[10]杨 丽,陈 洁,赵怀智,等.针灸治疗寻常型银屑病的临床研究进展[J].医学信息,2018,31(17):54.[doi:10.3969/j.issn.1006-1959.2018.17.017]
 YANG Li,CHEN Jie,ZHAO Huai-zhi,et al.Clinical Research Progress of Acupuncture for Psoriasis Vulgaris[J].Medical Information,2018,31(05):54.[doi:10.3969/j.issn.1006-1959.2018.17.017]

更新日期/Last Update: 1900-01-01