[1]黄丽玲,吴春城,梁惠卿,等.血清标志物壳多糖酶3样蛋白1评价肝纤维化的研究[J].医学信息,2021,34(10):32-35.[doi:10.3969/j.issn.1006-1959.2021.10.009]
 HUANG Li-ling,WU Chun-cheng,LIANG Hui-qing,et al.Serum Marker Chitinase 3-like Protein 1 in the Evaluation of Liver Fibrosis[J].Medical Information,2021,34(10):32-35.[doi:10.3969/j.issn.1006-1959.2021.10.009]
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血清标志物壳多糖酶3样蛋白1评价肝纤维化的研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年10期
页码:
32-35
栏目:
综述
出版日期:
2021-05-15

文章信息/Info

Title:
Serum Marker Chitinase 3-like Protein 1 in the Evaluation of Liver Fibrosis
文章编号:
1006-1959(2021)10-0032-04
作者:
黄丽玲吴春城梁惠卿
(1.福建中医药大学,福建 福州 350100;2.福建中医药大学附属厦门中医院感染性疾病科,福建 厦门 361009)
Author(s):
HUANG Li-lingWU Chun-chengLIANG Hui-qinget al.
(1.Fujian University of Traditional Chinese Medicine,Fuzhou 350100,Fujian,China;2.Department of Infectious Diseases,XiamenTraditional Chinese Medicine Hospital,Fujian University of Traditional Chinese Medicine,Xiamen 361009,Fujian,China)
关键词:
壳多糖酶3样蛋白1肝纤维化乙肝丙肝非酒精性脂肪肝肝癌
Keywords:
Chitinase 3-like protein 1Liver fibrosisHepatitis BHepatitis CNon-alcoholic fatty liverLiver cancer
分类号:
R563
DOI:
10.3969/j.issn.1006-1959.2021.10.009
文献标志码:
A
摘要:
壳多糖酶3样蛋白1(CHI3L1)是壳多糖酶家族的成员之一,能够分泌到肝脏的细胞外基质,在肝脏中高度表达,对各种肝病的纤维化诊断具有很好的价值。近年来,诊断和评估肝纤维化的相关检查存在局限性,让血清标志物CHI3L1越来越受关注,本文就CHI3L1在肝纤维化诊断中的作用以及与慢性乙型肝炎、慢性丙型肝炎、非酒精性脂肪肝、肝癌的关系作一综述,为临床治疗提供参考。
Abstract:
Chitinase 3-like protein 1 (CHI3L1) is a member of the chitinase family. It can be secreted into the extracellular matrix of the liver and is highly expressed in the liver. It is of great value for the diagnosis of fibrosis of various liver diseases.In recent years, there are limitations in the diagnosis and evaluation of liver fibrosis. The serum marker CHI3L1 has attracted more and more attention.This article reviews the role of CHI3L1 in the diagnosis of liver fibrosis and its relationship with chronic hepatitis B, chronic hepatitis C, non-alcoholic fatty liver, liver cancer, and provides references for clinical treatment.

参考文献/References:

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更新日期/Last Update: 1900-01-01