[1]滕若凌,赵 杰.全髋关节置换术前血脂水平与术后引流的关系[J].医学信息,2023,36(10):84-87.[doi:10.3969/j.issn.1006-1959.2023.10.019]
　TENG Ruo-ling,ZHAO Jie.Relationship Between Preoperative Blood Lipid Level and Postoperative Drainage in Total Hip Arthroplasty[J].Journal of Medical Information,2023,36(10):84-87.[doi:10.3969/j.issn.1006-1959.2023.10.019]
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全髋关节置换术前血脂水平与术后引流的关系()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年10期
页码:
84-87
栏目:
论著
出版日期:
2023-05-15

文章信息/Info

Title:
Relationship Between Preoperative Blood Lipid Level and Postoperative Drainage in Total Hip Arthroplasty
文章编号:
1006-1959（2023）10-0084-04
作者:
滕若凌; 赵 杰
（1.常州市第一人民医院老年医学科，江苏 常州 213004；2.江苏大学附属武进医院/徐州医科大学武进临床学院骨科，江苏 常州 213164）
Author(s):
TENG Ruo-ling; ZHAO Jie
(1.Department of Geriatrics,the First People’s Hospital of Changzhou,Changzhou 213004,Jiangsu,China;2.Department of Orthopedics,Wujin Hospital Affiliated to Jiangsu University/The Wujin Clinical College ofXuzhou Medical University,Changzhou 213164,Jiangsu,China)
关键词:
全髋关节置换术; 术后引流量; 血脂; 股骨头坏死; 多元线性回归分析
Keywords:
Total hip arthroplasty; Postoperative drainage; Serum lipid levels; Aseptic necrosis of femoral head; Multiple linear regression analysis
分类号:
R687.4
DOI:
10.3969/j.issn.1006-1959.2023.10.019
文献标志码:
A
摘要:
目的 分析行全髋关节置换术患者的术前血脂水平与术后引流量之间的关系。方法 纳入2013年1月-2017年12月于常州市第一人民医院骨关节科行全髋关节置换术的704例患者，收集患者术前各项血脂水平、术后引流量等临床指标，通过多元线性回归分析术前血脂水平与术后引流量之间的关系。结果 全髋关节置换术患者的多元线性回归结果显示，甘油三酯（TG）（B=16.047，P=0.015）与术后引流量呈正相关。股骨头无菌性坏死患者的多元线性回归结果显示，TG（B=75.783，P＜0.001）和低密度脂蛋白胆固醇（B=86.952，P=0.023）与术后引流量呈正相关，载脂蛋白B（B=-370.495，P=0.007）与术后引流量呈负相关。结论 全髋关节置换术后关注患者的血脂水平，必要时启动降脂治疗，对减少术后出血有一定指导意义。
Abstract:
Objective To analyze the relationship between preoperative blood lipid level and postoperative drainage volume in patients undergoing total hip arthroplasty.Methods A total of 704 patients who underwent total hip arthroplasty in the Department of Orthopedics, the First People ’s Hospital of Changzhou from January 2013 to December 2017 were included. Clinical indicators such as preoperative blood lipid levels and postoperative drainage were collected. The relationship between preoperative blood lipid levels and postoperative drainage was analyzed by multiple linear regression.Results Multivariate linear regression analysis showed that triglyceride (TG) (B=16.047, P=0.015) was positively correlated with postoperative drainage. The results of multiple linear regression showed that TG (B=75.783, P<0.001) and low density lipoprotein cholesterol (B=86.952, P=0.023) were positively correlated with postoperative drainage, and apolipoprotein B (B=-370.495, P=0.007) was negatively correlated with postoperative drainage.Conclusion Paying attention to the blood lipid level of patients after total hip arthroplasty and initiating lipid-lowering therapy when necessary have certain guiding significance for reducing postoperative bleeding.

参考文献/References:

[1]Ferguson RJ,Palmer AJ,Taylor A,et al.Hip replacement[J].Lancet,2018,392(10158):1662-1671.[2]Yang M,Yan C,Niu N,et al.Analysis of the Need for Postoperative Drainage Application for Hip Arthroplasty: A Systematic Review and Meta-Analysis[J].Comput Math Methods Med,2022,2022:2069468.[3]Mei L,Li H,Zhu W,et al.Efficacy and safety of tranexamic acid in unilateral major revision total hip arthroplasty[J].Ann Palliat Med,2020,9(5):2466-2473.[4]Bradley KE,Ryan SP,Penrose CT,et al.Tranexamic acid or epsilon-aminocaproic acid in total joint arthroplasty? A randomized controlled trial[J].Bone Joint J,2019,101-B(9):1093-1099.[5]Liu J,Zhao J,Yan Y,et al.Effectiveness and safety of rivaroxaban for the prevention of thrombosis following total hip or knee replacement: A systematic review and meta-analysis[J].Medicine (Baltimore),2019,98(9):e14539.[6]Wu FM,Yin P,Yu X,et al.Comparison of Two Posterior Soft Tissue Repair Techniques to Prevent Dislocation after Total Hip Arthroplasty via the Posterolateral Approach[J].J Invest Surg,2021,34(5):513-521.[7]Aggarwal VK,Elbuluk A,Dundon J,et al.Surgical approach significantly affects the complication rates associated with total hip arthroplasty[J].Bone Joint J,2019,101-B(6):646-651.[8]Zan P,Yao JJ,Fan L,et al.Efficacy of a Four-Hour Drainage Clamping Technique in the Reduction of Blood Loss Following Total Hip Arthroplasty: A Prospective Cohort Study[J].Med Sci Monit,2017,23:2708-2714.[9]Lee SH,Lee GW,Seol YJ,et al.Comparison of Outcomes of Total Hip Arthroplasty between Patients with Ankylosing Spondylitis and Avascular Necrosis of the Femoral Head[J].Clin Orthop Surg,2017,9(3):263-269.[10]Boulet MM,Cheillan D,Di Filippo M,et al.Large triglyceride-rich lipoproteins from fasting patients with type 2 diabetes activate platelets[J].Diabetes Metab,2020,46(1):54-60.[11]Faizullin D,Valiullina Y,Salnikov V,et al.Direct interaction of fibrinogen with lipid microparticles modulates clotting kinetics and clot structure[J].Nanomedicine,2020,23:102098.[12]Schooling CM,Au Yeung SL,Zhao JV.Exploring Pleiotropic Effects of Lipid Modifiers and Targets on Measures of the Coagulation System with Genetics[J].Thromb Haemost,2022,122(8):1296-1303.[13]诸骏仁,高润霖,赵水平,等.中国成人血脂异常防治指南(2016年修订版)[J].中国循环杂志,2016,31(10):937-953.[14]中华医学会内分泌学分会肥胖学组.中国成人肥胖症防治专家共识[J].中华内分泌代谢杂志,2011,27(9):711-717.[15]Zeng Y,Si HB,Shen B,et al.Intravenous Combined with Topical Administration of Tranexamic Acid in Primary Total Hip Arthroplasty: A Randomized Controlled Trial[J].Orthop Surg,2017,9(2):174-179.[16]梁大伟,杨琼,裴佳,等.478例股骨头坏死患者流行病学调查研究[J].临床骨科杂志,2020,23(5):699-702.[17]Baek SH,Kim KH,Lee WK,et al.Abnormal Lipid Profiles in Nontraumatic Osteonecrosis of the Femoral Head: A Comparison with Osteoarthritis Using Propensity Score Matching[J].J Bone Joint Surg Am,2022,104(Suppl 2):19-24.[18]Wang XY,Ma TL,Chen KN,et al.Accumulation of LDL/ox-LDL in the necrotic region participates in osteonecrosis of the femoral head: a pathological and in vitro study[J].Lipids Health Dis,2021,20(1):167.[19]Kim JA,Kim JE,Song SH,et al.Influence of blood lipids on global coagulation test results[J].Ann Lab Med,2015,35(1):15-21.[20]Mussoni L,Baldassarre D,Mannucci L,et al.Relationship between fibrinolytic and metabolic variables: a study in patients attending a lipid clinic[J].Ann Med,2000,32(2):134-141.[21]Wu RW,Wang FS,Ko JY,et al.Comparative serum proteome expression of osteonecrosis of the femoral head in adults[J].Bone,2008,43(3):561-566.[22]Palmisano BT,Zhu L,Eckel RH,et al.Sex differences in lipid and lipoprotein metabolism[J].Mol Metab,2018,15:45-55.[23]Penrod NM,Poku KA,Vaughan DE,et al.Epistatic interactions in genetic regulation of t-PA and PAI-1 levels in a Ghanaian population[J].PLoS One,2011,6(1):e16639.

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更新日期/Last Update: 1900-01-01