[1]陈俊芬,肖欢智,陆廷飞,等.黄芪建中汤联合中药穴位贴敷治疗脾胃虚寒型慢性胃炎Meta分析[J].医学信息,2023,36(19):46-53.[doi:10.3969/j.issn.1006-1959.2023.19.010]
　CHEN Jun-fen,XIAO Huan-zhi,LU Ting-fei,et al.Meta-analysis of Huangqi Jianzhong Decoction Combined with Acupoint Application of Traditional Chinese Medicine in the Treatment of Chronic Gastritis of Spleen-stomach Deficiency-cold Type[J].Journal of Medical Information,2023,36(19):46-53.[doi:10.3969/j.issn.1006-1959.2023.19.010]
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黄芪建中汤联合中药穴位贴敷治疗脾胃虚寒型慢性胃炎Meta分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年19期
页码:
46-53
栏目:
医学数据科学
出版日期:
2023-10-01

文章信息/Info

Title:
Meta-analysis of Huangqi Jianzhong Decoction Combined with Acupoint Application of Traditional Chinese Medicine in the Treatment of Chronic Gastritis of Spleen-stomach Deficiency-cold Type
文章编号:
1006-1959（2023）19-0046-08
作者:
陈俊芬; 肖欢智; 陆廷飞; 等
（1.贵州中医药大学第一临床医学院，贵州 贵阳 550000；2.贵州中医药大学第一附属医院消化内科，贵州 贵阳 550000）
Author(s):
CHEN Jun-fen; XIAO Huan-zhi; LU Ting-fei; et al.
(1.The First Clinical Medical College of Guizhou University of Traditional Chinese Medicine,Guiyang 550000,Guizhou,China;2.Department of Gastroenterology,the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550000,Guizhou,China)
关键词:
黄芪建中汤; 穴位贴敷; 脾胃虚寒; 慢性胃炎
Keywords:
Huangqi Jianzhong decoction; Acupoint application; Deficiency of spleen and stomach; Chronic gastritis
分类号:
R573.3
DOI:
10.3969/j.issn.1006-1959.2023.19.010
文献标志码:
A
摘要:
目的 评估黄芪建中汤联合中药穴位贴敷治疗脾胃虚寒型慢性胃炎的临床疗效。方法 计算机检索中国知网、万方数据库、超星期刊、维普网、中国生物医学数据库有关黄芪建中汤联合中药穴位贴敷治疗脾胃虚寒型慢性胃炎的相关文献，检索时限为建库至2022年9月，并筛选以常规西药或黄芪建中汤作为对照组的随机对照试验为研究对象，参照Cochrane手册对纳入文献进行质量评价，采用Review Manager 5.4软件进行Meta分析。结果 最终纳入文献10篇，共928例受试者。10篇文献试验组干预措施均为黄芪建中汤联合中药穴位贴敷，7篇文献对照组干预措施为常规西药，3篇文献对照组干预措施为黄芪建中汤。Meta分析显示，试验组临床有效率高于对照组，差异有统计学意义（OR＝4.46，95%CI：2.90~6.84，P＜0.000 01）；试验组临床治愈率高于对照组，差异有统计学意义（OR＝2.55，95%CI：1.80~3.62，P＜0.000 01）；试验组对于临床症状、体征的改善效果均优于对照组（P＜0.05）；试验组对于血清PGⅠ（OR＝12.21，95%CI：8.05~16.37，P＜0.000 01）、血清PGⅡ（OR＝0.02，95%CI：-0.51~0.55，P=0.94）、血清GS（OR＝2.81，95%CI：2.05~3.57，P＜0.000 01）的改善效果均优于对照组；试验组不良反应发生率（OR＝0.12，95%CI：0.03~0.55，P＜0.05）低于对照组。结论 相较于采用常规西药和黄芪建中汤治疗的对照组，黄芪建中汤联合中药穴位贴敷对于治疗脾胃虚寒型慢性胃炎临床效果更好。
Abstract:
Objective To evaluate the clinical efficacy of Huangqi Jianzhong decoction combined with acupoint application of traditional Chinese medicine in the treatment of chronic gastritis of spleen-stomach deficiency-cold type.Methods The relevant literatures on Huangqi Jianzhong Decoction combined with acupoint application of traditional Chinese medicine in the treatment of chronic gastritis of spleen and stomach deficiency cold type were searched by computer from China National Knowledge Infrastructure, Wanfang Database, Superstar Journal, VIP Network and China Biomedical Database. The retrieval time limit was from the establishment of the database to September 2022, and the randomized controlled trials with conventional western medicine or Huangqi Jianzhong Decoction as the control group were selected as the research objects. The quality of the included literatures was evaluated according to the Cochrane manual, and Meta-analysis was performed using Review Manager 5.4 software.Results Finally, 10 literatures were included, with a total of 928 bsubjects. In 10 literatures, the intervention measures of the experimental group were Huangqi Jianzhong decoction combined with acupoint application of traditional Chinese medicine, the intervention measures of the control group in 7 literatures were conventional western medicine, and the intervention measures of the control group in 3 literatures were Huangqi Jianzhong Decoction. Meta-analysis showed that the clinical effective rate of the experimental group was higher than that of the control group, and the difference was statistically significant （OR＝4.46，95%CI：2.90-6.84，P＜0.000 01）； the clinical cure rate of the experimental group was higher than that of the control group, and the difference was statistically significant（OR＝2.55，95%CI：1.80-3.62，P＜0.000 01）; the improvement of clinical symptoms and signs in the experimental group was better than that in the control group (P<0.05); the improvement of serum PGⅠ （OR＝12.21，95%CI：8.05-16.37，P＜0.000 01）, serum PGⅡ （OR＝0.02，95%CI：-0.51-0.55，P=0.94） and serum GS （OR＝2.81，95%CI：2.05-3.57，P＜0.000 01） in the experimental group was better than that in the control group;the incidence of adverse reactions in the experimental group (OR＝0.12,95%CI:0.03-0.55,P<0.05).Conclusion Compared with the control group treated with conventional western medicine and Huangqi Jianzhong decoction, Huangqi Jianzhong decoction combined with acupoint application of traditional Chinese medicine is more effective in the treatment of chronic gastritis of spleen-stomach deficiency-cold type.

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