[1]张小凌,黄青兰.缩宫素联合益母草注射液对高龄产妇产后出血及凝血功能的影响[J].医学信息,2023,36(24):121-124.[doi:10.3969/j.issn.1006-1959.2023.24.027]
　ZHANG Xiao-ling,HUANG Qing-lan.Effect of Oxytocin Combined with Motherwort Injection on Postpartum Hemorrhage and Coagulation Function in Elderly Parturient Women[J].Journal of Medical Information,2023,36(24):121-124.[doi:10.3969/j.issn.1006-1959.2023.24.027]
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缩宫素联合益母草注射液对高龄产妇产后出血及凝血功能的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年24期
页码:
121-124
栏目:
中医中药
出版日期:
2023-12-15

文章信息/Info

Title:
Effect of Oxytocin Combined with Motherwort Injection on Postpartum Hemorrhage and Coagulation Function in Elderly Parturient Women
文章编号:
1006-1959（2023）24-0121-04
作者:
张小凌; 黄青兰
（余干县人民医院妇产科，江西 余干 335100）
Author(s):
ZHANG Xiao-ling; HUANG Qing-lan
(Department of Obstetrics and Gynecology,Yugan County People’s Hospital,Yugan 335100,Jiangxi,China)
关键词:
缩宫素; 益母草注射液; 高龄产妇; 产后出血; 凝血功能
Keywords:
Oxytocin; Motherwort injection; Elderly parturient women; Postpartum hemorrhage; Blood coagulation function
分类号:
R714
DOI:
10.3969/j.issn.1006-1959.2023.24.027
文献标志码:
A
摘要:
目的 观察缩宫素联合益母草注射液对高龄产妇产后出血及凝血功能的影响。方法 选取2020年1月-2022年6月于我院分娩的60例高龄产妇为研究对象，采用随机数字表法分为对照组（n=30）和观察组（n=30）。对照组采用缩宫素治疗，观察组在对照组基础上联合益母草注射液治疗，比较两组产后出血发生率、不同时间段出血量、凝血功能指标[活化部分凝血活酶时间（APTT）、凝血酶原时间（PT）、纤维蛋白原（FBG）]、宫缩和恶露持续时间、子宫复旧情况、不良反应发生率。结果 观察组出血发生率为6.67%,低于对照组16.67%（P＜0.05）；观察组产后2、24 h出血量均小于对照组（P＜0.05）；观察组APTT、PT小于对照组，FBG高于对照组（P＜0.05）；观察组宫缩持续时间长于对照组，恶露持续时间短于对照组（P＜0.05）；观察组产后2、6 d子宫底与耻骨联合上缘中点垂直高度低于对照组（P＜0.05）；观察组不良反应发生率低于对照组（P＜0.05）。结论 缩宫素联合益母草注射液可有效预防高龄产妇产后出血发生，减少产后24 h内出血量，一定程度改善凝血功能，促进宫缩，缩短恶露持续时间，降低不良反应发生率，具有良好的应用有效性、安全性。
Abstract:
Objective To observe the effect of oxytocin combined with motherwort injection on postpartum hemorrhage and coagulation function in elderly parturient women.Methods Sixty elderly parturient women who gave birth in our hospital from January 2020 to June 2022 were selected as the research objects. They were divided into control group (n=30) and observation group (n=30) by random number table method. The control group was treated with oxytocin, and the observation group was treated with motherwort injection on the basis of the control group. The incidence of postpartum hemorrhage, bleeding volume at different time periods, coagulation function indexes [activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen (FBG)], duration of uterine contraction and lochia, uterine involution and incidence of adverse reactions were compared between the two groups.Results The incidence of bleeding in the observation group was 6.67%, which was lower than 16.67% in the control group (P<0.05). The amount of bleeding at 2 and 24 hours after delivery in the observation group was less than that in the control group (P<0.05). APTT and PT in the observation group were lower than those in the control group, and FBG was higher than that in the control group (P<0.05). The duration of uterine contraction in the observation group was longer than that in the control group, and the duration of lochia was shorter than that in the control group (P<0.05). The vertical height of the uterine fundus and the midpoint of the upper edge of the pubic symphysis in the observation group was lower than that in the control group at 2 and 6 days after delivery (P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05).Conclusion Oxytocin combined with motherwort injection can effectively prevent postpartum hemorrhage in elderly parturient women, reduce the amount of bleeding within 24 hours after delivery, improve coagulation function to a certain extent, promote uterine contraction, shorten the duration of lochia, and reduce the incidence of adverse reactions. It has good application effectiveness and safety.

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更新日期/Last Update: 1900-01-01