[1]纪东华,宁国贤.贝那普利联合美托洛尔治疗CHF的效果及对心室重构影响[J].医学信息,2019,32(14):156-157.[doi:10.3969/j.issn.1006-1959.2019.14.052]
 JI Dong-hua,NING Guo-xian.Effect of Benazepril Combined with Metoprolol on Ventricular Remodeling in Patients with CHF[J].Journal of Medical Information,2019,32(14):156-157.[doi:10.3969/j.issn.1006-1959.2019.14.052]
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贝那普利联合美托洛尔治疗CHF的效果及对心室重构影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年14期
页码:
156-157
栏目:
药物与临床
出版日期:
2019-07-15

文章信息/Info

Title:
Effect of Benazepril Combined with Metoprolol on Ventricular Remodeling in Patients with CHF
文章编号:
1006-1959(2019)14-0156-02
作者:
纪东华宁国贤
佳木斯市中心医院心内科,黑龙江 佳木斯 154002
Author(s):
JI Dong-huaNING Guo-xian
Department of Cardiology,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China
关键词:
心力衰竭贝那普利美托洛尔心室重构
Keywords:
Key words:Heart failureBenazeprilMetoprololVentricular remodeling
分类号:
R541.6
DOI:
10.3969/j.issn.1006-1959.2019.14.052
文献标志码:
A
摘要:
目的 研究慢性心力衰竭(CHF)患者应用贝那普利与美托洛尔的效果。方法 选取2017年10月~2018年10月我院收治的196例CHF患者为研究对象,采用随机数表法分为观察组和对照组,各98例。两组均给予常规抗心衰药物治疗,对照组加服美托洛尔,观察组加服贝那普利联合美托洛尔治疗,比较两组治疗半年后临床疗效及左室射血分数(LVEF)、左室收缩末期内径(LVESD)和左室舒张末期内径(LVEDD)改善情况。结果 观察组治疗总有效率为94.89%,高于对照组83.67%(P<0.05);治疗后,观察组LVEF高于对照组,LVESD、LVEDD均低于对照组(P<0.05)。结论 联合应用贝那普利联合、美托洛尔治疗CHF能够提高心力衰竭患者的心脏泵血功能,逆转心室重构。
Abstract:
Abstract:Objective To study the effects of combined use of benazepril and metoprolol in patients with chronic heart failure (CHF). Methods A total of 196 patients with CHF admitted to our hospital from October 2017 to October 2018 were enrolled in the study. They were randomly divided into observation group and control group, 98 cases each. The two groups were given conventional anti-heart failure drugs. The control group was treated with metoprolol. The observation group was treated with benazepril combined with metoprolol. The clinical efficacy and left ventricular ejection fraction were compared after treatment for half a year (LVEF), left ventricular end-systolic diameter (LVESD), and left ventricular end-diastolic diameter (LVEDD) improvement.Results The total effective rate of the observation group was 94.89%, which was higher than that of the control group 83.67%(P<0.05). After treatment, the LVEF of the observation group was higher than that of the control group, and the LVESD and LVEDD were lower than the control group(P<0.05).Conclusion Combined application of benazepril and metoprolol can improve cardiac pumping function and reverse ventricular remodeling in patients with heart failure.

参考文献/References:

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更新日期/Last Update: 2019-07-15